Panizox (20mg) 14 Tablets

Pantoprazole 20mg tablets work by acting as a proton pump inhibitor, specifically targeting the H+/K+-ATPase (proton pump) in the stomach's parietal cells. This pump is responsible for the final step of gastric acid secretion. Pantoprazole binds to the proton pump, effectively blocking its function and inhibiting the secretion of gastric acid. By suppressing the production of stomach acid, pantoprazole helps to reduce the acidity in the stomach, providing relief from conditions such as acid reflux, gastroesophageal reflux disease (GERD), and peptic ulcers, where excessive acid production is a contributing factor.

Proton pump inhibitor.

Tablet

The following are the uses of Pantoprazole 20mg Tablet:

• Used for treating acid reflux and heartburn.
• Used to manage symptoms of gastroesophageal reflux disease (GERD).
• Used for reducing stomach acid and promoting healing of stomach ulcers.
• Used in the prevention of upper gastrointestinal bleeding.
• Used to treat conditions where the stomach produces too much acid.
• Used for relieving acid-related discomfort in the throat.
• Used to aid in the healing of erosive esophagitis.

In the case of an overdose of Pantoprazole 20mg Tablets, individuals may experience an increase in the severity of common side effects such as headaches, diarrhea, and abdominal pain. Additionally, more serious symptoms like confusion, dizziness, and an irregular heartbeat might occur. It is important to promptly seek medical advice or contact a healthcare professional for guidance on managing the overdose and preventing potential complications. Timely intervention can help mitigate the risks associated with excessive Pantoprazole intake.

In the case of a missed dose of Pantoprazole 20mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To take Pantoprazole 20mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning before a meal, following the dosage instructions provided by your healthcare professional.

Following are the conditions when Pantoprazole 20mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Pantoprazole or other proton pump inhibitors (PPIs).
• Contraindicated in patients with severe liver problems, as the medication is primarily metabolized by the liver.
• Not recommended for long-term use without medical supervision due to potential vitamin B12 deficiency and other long-term effects.
• Should be avoided in patients with low magnesium levels or conditions that cause low magnesium, as prolonged use may further decrease magnesium levels.
• Contraindicated in patients with a rare condition called Zollinger-Ellison syndrome.
• Not suitable for individuals who are currently taking a medication that contains rilpivirine.

The side effects of Pantoprazole 20mg Tablet may include:

• Headache
• Diarrhea
• Nausea
• Abdominal pain
• Dizziness
• Skin rashes
• Increased liver enzymes
• Peripheral edema

Following are the precautions and warnings for Pantoprazole 20mg Tablet:

• Do not take this medication if you are allergic to Pantoprazole or other proton pump inhibitors.
• Long-term use may lead to vitamin B12 deficiency, so regular monitoring is necessary.
• Inform your doctor if you have any liver or kidney problems as dosage adjustments may be required.
• Caution is advised for elderly patients as they may be more susceptible to side effects.
• It may interact with other medications, so inform your doctor about all the medicines you are currently taking.
• This medication may cause bone fractures when used long-term, especially in high doses.
• Pregnant and breastfeeding women should consult their doctor before taking this medicine as it may affect fetal development and pass into breast milk.

Following are the drug interactions for Pantoprazole 20mg Tablet:

• Concomitant use with Clopidogrel may reduce the effectiveness of Clopidogrel, potentially increasing the risk of cardiovascular events.
• May decrease absorption of drugs that require a higher pH for absorption, such as Ketoconazole and Atazanavir.
• Pantoprazole can reduce the effectiveness of Methotrexate by decreasing its absorption.
• It can increase plasma concentrations of drugs metabolized by CYP2C19 and CYP3A4 enzymes, including Diazepam, Phenytoin, and Warfarin.
• The absorption of some antibiotics like Erythromycin and Ampicillin may be reduced when taken with Pantoprazole.
• Prolonged use with Digoxin can increase Digoxin levels, requiring monitoring.
• May delay elimination of Theophylline, increasing its concentration in the body.

Following are the food interactions for Pantoprazole 20mg Tablet:

• Avoid excessive consumption of acidic foods like citrus fruits, tomatoes, and their juices, as they can irritate the stomach and potentially reduce the effectiveness of Pantoprazole.
• Alcohol should be limited or avoided as it can increase stomach acid production and may reduce the medication's efficacy.
• Caffeinated beverages such as coffee, tea, and soda should be reduced as they can stimulate acid secretion and potentially counteract the effects of the medication.
• Spicy foods may trigger acid reflux and heartburn, so it's advisable to limit their intake while taking Pantoprazole.
• High-fat meals can delay stomach emptying and potentially affect the absorption of Pantoprazole, so it's best to consume them in moderation.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Pantoprazole, leading to increased levels of the drug in the body and potential side effects.
• Dairy products, especially those high in fat, may cause discomfort for some individuals with gastrointestinal issues, so moderation is recommended.
• Maintaining a balanced diet with whole grains, lean proteins, and plenty of vegetables can support overall digestive health during Pantoprazole therapy.

Pantoprazole 20mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to keep the medication away from heat sources like ovens or radiators, as temperature fluctuations can impact its effectiveness. Regularly check the expiration date, and for proper disposal, do not flush or pour the medication down the drain; instead, consult a pharmacist or healthcare professional for guidance. Always keep medicines out of children's reach to prevent accidental consumption.

Following are the quick tips for Pantoprazole 20mg Tablet:

• Consult your doctor before use, especially if you have liver problems or are pregnant/breastfeeding.
• Take the tablet as directed by your doctor, typically once daily before a meal.
• Swallow the tablet whole with a glass of water; do not crush or chew it.
• Avoid missing doses; take it at the same time each day to maintain effectiveness.
• Inform your doctor about all medications you're taking to prevent potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.