PANOCID DROPS 10%

Sulfacetamide, the active ingredient in Sulfacetamide Drops, primarily acts as a sulfonamide antibiotic. Its mechanism of action involves inhibiting the synthesis of folic acid in susceptible bacteria. Specifically, sulfacetamide competes with the naturally occurring substrate, para-aminobenzoic acid (PABA), and binds to the enzyme dihydropteroate synthase, thereby preventing the conversion of PABA into folic acid. This disruption in folic acid production inhibits bacterial growth and proliferation, as folic acid is essential for the synthesis of nucleic acids (DNA and RNA) and proteins in bacteria. By targeting this unique aspect of bacterial metabolism, sulfacetamide exhibits its antimicrobial activity, making it effective against a range of bacteria, particularly those associated with ocular infections.

Sulfonamide antibiotic

Drop

The following are the uses of Sulfacetamide Drop:

• Used for treating eye infections such as conjunctivitis.
• Used for reducing eye inflammation and irritation.
• Used for preventing bacterial growth and controlling eye infections.
• Used for managing chronic eye conditions like blepharitis.
• Used for post-surgery eye care to prevent infection.
• Used for providing temporary relief from eye discomfort.
• Used for promoting faster healing of eye injuries.
• Used for maintaining eye health and preventing further complications.

In the case of an overdose of Sulfacetamide Drops, it is important to remain calm and take immediate action. Seek medical advice promptly, and provide the healthcare professional with all relevant information, including the dosage taken. They will be able to provide specific guidance and treatment based on the individual's condition and the severity of the overdose. Quick action can help mitigate potential health risks associated with excessive use of this medication.

In the case of a missed dose of Sulfacetamide Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra drops or increase the frequency to make up for the missed dose. If you miss several doses, contact your healthcare provider for guidance on how to proceed and ensure you are using the medication correctly. It is best to maintain a consistent schedule for optimal effectiveness.

To use Sulfacetamide Drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and instill the prescribed number of drops into the eye, then close your eyes gently to distribute the medication.

Following are the conditions/situations when Sulfacetamide eye drops should not be used:

• Should not be used if you are allergic to sulfa drugs or any other ingredients in the eye drops.
• Not suitable for individuals with a history of severe asthma or allergies.
• Contraindicated for infants younger than 2 months old.
• Avoid using these drops if you have a corneal ulcer or herpes simplex keratitis.
• Do not use if you have a bacterial or viral infection of the eye that is not responsive to sulfacetamide.
• Not recommended for those with a history of Stevens-Johnson syndrome or toxic epidermal necrolysis.
• Should not be used if you have a perforated or damaged eardrum (when used for ear infections).
• Avoid using these drops if you have a condition that affects the cornea, such as dry eye syndrome or corneal erosion.

The side effects of Sulfacetamide Eye Drops may include:

• Eye irritation or redness
• Burning or stinging sensation in the eye
• Temporary blurred vision
• Itchy or watery eyes
• Increased sensitivity to light
• Dry eyes
• Allergic reactions, such as skin rash or itching

Following are the precautions and warnings for Sulfacetamide Eye Drops:

• Do not use if you are allergic to sulfonamides or any ingredients in the eye drops.
• Remove contact lenses before application, and wait at least 15 minutes after use before reinserting them.
• Avoid touching the dropper tip to any surface to prevent contamination.
• Prolonged use may result in the overgrowth of non-susceptible organisms, including fungi.
• Do not use the eye drops if the solution becomes cloudy or discolored.
• Discontinue use and consult a doctor if you experience severe or persistent eye irritation, pain, or changes in vision.
• Keep out of reach of children and pets.

Following are the drug interactions for Sulfacetamide Drop:

• Concomitant use with silver preparations or zinc-containing eye medications may cause a temporary yellow-brown discoloration of the conjunctiva.
• Sulfonamides may decrease the efficacy of oral anticoagulants, requiring closer monitoring of prothrombin time.
• The risk of bleeding may increase when used with anticoagulants or thrombolytic agents.
• Sulfacetamide may interfere with urinary glucose tests based on cupric sulfate benzoate reactions, resulting in false-positive results.
• The use of sulfonamides with methenamine may increase the risk of crystalluria and stone formation.
• When combined with antidiabetic drugs, sulfonamides may prolong prothrombin time.
• Sulfacetamide may decrease the excretion of methotrexate, potentially increasing its toxicity.

Following are the food interactions for Sulfacetamide Drops:

• Alcohol should be avoided as it can lead to increased drowsiness and dizziness.
• Sulfacetamide may cause stomach upset, so it is advisable to take the medication with food to minimize this side effect.
• Avoid consuming dairy products, calcium-fortified juices, and antacids containing calcium within 2 hours of taking the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they may alter the effectiveness of the medication.
• Avoid high-sodium foods as Sulfacetamide may cause sodium retention.
• Avoid vitamin C supplements and citrus fruits, as they can affect the pH balance and reduce the efficacy of the drops.
• Always follow the dosage instructions provided by your healthcare professional regarding food and medication timing.

Sulfacetamide Drops should be stored with utmost care, preferably in a clean, dry area at room temperature, shielded from direct sunlight and moisture. It is crucial to maintain the original container's tight seal to prevent contamination. Avoid bathroom storage or proximity to heat sources like stoves or radiators, as temperature fluctuations can compromise the medication's integrity. Prior to use, verify the packaging's expiration date, and responsibly dispose of any unused or expired drops; refrain from flushing them down the toilet or pouring them into drains. Consult your pharmacist or healthcare provider for safe disposal practices, and ensure the medication is inaccessible to children to prevent accidental ingestion.

Following are the quick tips for Sulfacetamide Drops:

• Wash your hands before and after using the eye drops to maintain hygiene.
• Tilt your head back, gently pull your lower eyelid down, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If you wear contact lenses, remove them before using the drops and wait at least 15 minutes before reinserting them.
• Do not rinse the dropper; replace the cap after each use.
• Store the drops at room temperature, away from direct sunlight and moisture.
• Inform your doctor if you have any eye infections or allergies before using these drops.