PanOxyl Aquagel 10 (10%) 40g Gel

Benzoyl Peroxide Gel works primarily through its potent bactericidal activity against the bacteria Propionibacterium acnes, which is a key contributor to acne development. Its mechanism of action involves the release of oxygen-free radicals when it comes into contact with the skin, leading to the oxidation and destruction of the bacteria's cellular components. This process specifically targets P. acnes due to its sensitivity to oxidative stress. Additionally, Benzoyl Peroxide Gel exhibits mild comedolytic properties, helping to break down and remove excess sebum and dead skin cells that can clog pores and contribute to acne formation. By reducing the presence of P. acnes and clearing the skin of comedones, the gel effectively treats and prevents acne lesions.

Benzoyl Peroxide

Topical acne treatment

Gel

The following are the uses of Benzoyl Peroxide Gel:

• Used for treating acne and reducing inflammation
• Used to unclog pores and prevent new acne lesions
• Used for exfoliating the skin and removing dead skin cells
• Used as an antibacterial agent to kill acne-causing bacteria
• Used to reduce the appearance of blackheads and whiteheads
• Used for improving overall skin texture and tone
• Used in combination with other acne treatments for enhanced results
• Used for preventing acne breakouts in prone areas

In the case of an overdose of Benzoyl Peroxide Gel, individuals may experience skin irritation, redness, and peeling. Symptoms typically include an intense burning sensation at the application site, which can spread to surrounding areas. If ingested, nausea, vomiting, and stomach discomfort might occur. It is advisable to remove any remaining gel and seek medical advice promptly. Timely intervention can help manage symptoms effectively and prevent further complications.

In the case of a missed dose of Benzoyl Peroxide Gel, it is generally recommended to apply the medication as soon as you remember. However, if it's almost time for your next dose, skip the missed application and continue with your regular schedule. Do not apply extra gel to make up for the missed dose, as this may increase the risk of skin irritation. Simply resume your regular application schedule and ensure you follow the prescribed instructions for the best results. Consult your healthcare provider if you frequently miss doses or have concerns about the effectiveness of the treatment.

To use Benzoyl Peroxide Gel, gently cleanse the affected skin area, then apply a thin layer of the gel, ensuring you cover the entire area, and allow it to dry; follow this routine twice daily or as directed by your healthcare provider.

Here are the situations or conditions when Benzoyl Peroxide Gel should not be used:

• Avoid using if you have a known allergy or sensitivity to benzoyl peroxide or any other ingredients in the gel formulation.
• Not suitable for individuals with severely dry or irritated skin.
• Avoid using on broken or wounded skin.
• Do not use around the eye area, including the eyelids, as it can cause severe irritation.
• Contraindicated for infants or very young children without medical advice.
• Do not use if you are taking other topical medications without consulting a healthcare professional.
• Avoid using on skin conditions like eczema or severe acne without medical supervision.
• Discontinue use if you experience severe skin reactions, burning, or excessive peeling.

The side effects of Benzoyl Peroxide Gel may include:

• Skin irritation
• Redness and swelling at the application site
• Dryness and peeling of the skin
• Itching or burning sensation
• Allergic reactions (skin rash, hives)
• Temporary skin discoloration
• Increased sensitivity to sunlight

Following are the precautions and warnings for Benzoyl Peroxide Gel:

• Avoid contact with eyes, mouth, and other mucous membranes. In case of accidental contact, rinse thoroughly with water.
• Do not use on broken or irritated skin. Discontinue use if excessive dryness, redness, or peeling occurs.
• This product may cause increased sensitivity to sunlight. Avoid prolonged sun exposure and use sunscreen when outdoors.
• Do not use this medication if you are allergic to Benzoyl Peroxide or any of its ingredients.
• Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
• Benzoyl Peroxide may bleach hair or fabrics. Take care to avoid contact with clothing, towels, and bedding.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.

Following are the drug interactions for Benzoyl Peroxide Gel:

• When used with topical antibiotics like Clindamycin or Erythromycin, it may reduce the effectiveness of the antibiotic.
• Avoid using other topical medications without consulting a doctor, as it may cause skin irritation.
• Skin products containing alcohol, astringents, or spices can cause excessive dryness and irritation.
• Combination with other benzoyl peroxide-containing products may increase the risk of skin peeling and redness.
• Topical retinoids, such as Tretinoin, may cause increased skin sensitivity and irritation.
• Certain hair removal products or procedures can cause skin sensitivity and irritation when used with Benzoyl Peroxide Gel.
• Consult a doctor if using peeling agents (e.g., salicylic acid, glycolic acid) to avoid excessive skin exfoliation.

Following are the food interactions for Benzoyl Peroxide Gel:

• Benzoyl Peroxide Gel can cause skin dryness, so consuming foods rich in antioxidants like berries, citrus fruits, and leafy greens can help combat oxidative stress and support skin health.
• Avoid excessive sun exposure as Benzoyl Peroxide can increase sun sensitivity. Wear protective clothing and use sunscreen when going outdoors.
• Some studies suggest that a diet high in sugar and refined carbohydrates may contribute to acne. Consider reducing sugar intake for better skin results.
• Dairy products might trigger acne for some individuals. Consider limiting dairy to observe any improvements in skin condition.
• Including foods rich in omega-3 fatty acids like salmon, chia seeds, and walnuts can help reduce inflammation and support skin health.
• Staying well-hydrated by drinking adequate water can contribute to overall skin health and help reduce skin dryness.
• A balanced diet with a variety of fruits, vegetables, whole grains, and lean proteins can provide essential nutrients for skin health and overall well-being.

Benzoyl Peroxide Gel should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from direct sunlight and heat. Keep the gel in its original container, tightly sealed, to maintain its integrity and prevent contamination. Always check the expiration date before use and avoid using it if it has expired. When disposing of the gel, do not flush it down the toilet or pour it into drains. Instead, follow local guidelines or consult your pharmacist for safe disposal methods to minimize environmental impact. Keep the gel out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Benzoyl Peroxide Gel:

• Clean and dry the affected area before applying the gel.
• Use a small amount of gel and gently rub it into the skin, avoiding sensitive areas like eyes and mouth.
• Apply once or twice daily as directed by your healthcare provider.
• Wash your hands thoroughly after application to avoid accidental contact with eyes or other sensitive areas.
• Avoid using other acne medications or harsh skincare products simultaneously to prevent skin irritation.
• Do not cover the treated area with bandages or tight clothing.
• Regular use may cause dryness; adjust application frequency if needed.