Paroxin (20mg) 10 Tablets

Paroxin (20mg) 10 Tablets

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  • Manufacturer Amarant Pharmaceuticals (Pvt.) Ltd.
  • Generic Name

    Paroxetine 20mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Paroxetine 20mg Tablet is a selective serotonin reuptake inhibitor (SSRI). It works by inhibiting the reuptake of serotonin, a neurotransmitter, in the brain. By increasing serotonin levels in the synaptic cleft, Paroxetine enhances serotonergic neurotransmission, which is thought to contribute to its antidepressant, anxiolytic, and mood-stabilizing effects. This mechanism helps alleviate symptoms of depression, anxiety, and other related disorders by promoting balanced serotonin activity in the brain.

  • Ingredients

    Paroxetine 20mg

  • Drug Class

    Selective Serotonin Reuptake Inhibitors (SSRIs)

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Paroxetine 20mg Tablet:

    • Treatment of major depressive disorder (MDD) in adults.
    • Management of generalized anxiety disorder (GAD).
    • Treatment of obsessive-compulsive disorder (OCD).
    • Management of panic disorder with or without agoraphobia.
    • Treatment of social anxiety disorder (social phobia).
    • Management of post-traumatic stress disorder (PTSD).
    • Treatment of premenstrual dysphoric disorder (PMDD).
  • Dosage

    Following are the doses of Paroxetine 20mg Tablet:

    • The usual starting dose for adults is 20mg once daily, typically taken in the morning with or without food.
    • In cases where the symptoms do not improve, the dose may be increased gradually by 10mg per day, not exceeding 40mg per day.
    • For elderly patients or those with liver impairment, a lower dose may be recommended to avoid side effects.
  • In case of Overdose

    In case of an overdose of Paroxetine 20mg Tablet, immediate medical attention should be sought. Overdose symptoms may include dizziness, nausea, vomiting, tremors, increased heart rate, and confusion. If an overdose is suspected, do not attempt to induce vomiting or take any other action without first consulting a healthcare provider.

  • Missed Dose

    If you miss a dose of Paroxetine 20mg Tablet, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a missed dose, as this may increase the risk of side effects.

  • How To Use

    To use Paroxetine 20mg Tablet, follow the instructions provided by your healthcare provider or as indicated on the prescription label. Typically, the tablet should be taken once daily, in the morning, with or without food. Swallow the tablet whole with a glass of water, and do not chew or crush it. It is important to take the medication at the same time each day to help you remember and maintain consistent levels in your body. Do not stop the medication abruptly without consulting your healthcare provider, as sudden discontinuation can lead to withdrawal symptoms.

  • When Not to Use

    Following are the situations when Paroxetine 20mg Tablet should not be used:

    • Should not be used in individuals with a known allergy to Paroxetine or any of its components.
    • Contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI therapy.
    • Should not be used in individuals with a history of bipolar disorder or mania.
    • Contraindicated in individuals who have experienced suicidal thoughts or behavior during antidepressant treatment.
    • Should not be used in children under 18 years of age unless specifically prescribed by a healthcare provider.
  • Side Effects

    The side effects of Paroxetine 20mg Tablet may include:

    • Nausea
    • Drowsiness
    • Dry mouth
    • Insomnia
    • Dizziness
    • Sweating
    • Sexual dysfunction (e.g., reduced libido, erectile dysfunction)
    • Weight gain
    • Tremors
    • Increased anxiety or agitation (especially during the initial phase of treatment)
    • Risk of suicidal thoughts or behavior, particularly in younger individuals
    • Gastrointestinal disturbances (e.g., constipation, diarrhea)
  • Precautions & Warnings

    Following are the precautions and warnings for Paroxetine 20mg Tablet:

    • Should not be used in individuals with a known allergy to Paroxetine or any of its ingredients.
    • Contraindicated in patients who are currently taking monoamine oxidase inhibitors (MAOIs) or have taken them within the past 14 days due to the risk of serotonin syndrome.
    • Caution is advised in patients with a history of bipolar disorder, as it may precipitate a manic episode.
    • Paroxetine should be used with caution in individuals with a history of seizures, as it may lower the seizure threshold.
    • Caution is also advised for those with liver or kidney impairment, as Paroxetine is primarily metabolized in the liver.
    • It may increase the risk of bleeding when used concurrently with anticoagulants or antiplatelet drugs.
    • Use with caution in elderly patients, as they may be more sensitive to the medication’s side effects, particularly sedation and dizziness.
    • Discontinuation of Paroxetine should be gradual to minimize withdrawal symptoms. Consult your healthcare provider before stopping the medication.
  • Drug Interactions

    Following are the drug interactions for Paroxetine 20mg Tablet:

    • Concomitant use of Paroxetine with other serotonergic drugs (e.g., other SSRIs, SNRIs, triptans, or tramadol) can increase the risk of serotonin syndrome, a potentially life-threatening condition.
    • Caution is advised when using Paroxetine with anticoagulants or antiplatelet drugs (e.g., warfarin, aspirin), as it may increase the risk of bleeding.
    • Combining Paroxetine with monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of serious interactions, including serotonin syndrome.
    • Use of Paroxetine with alcohol or central nervous system depressants (e.g., benzodiazepines, opioids) may increase the sedative effects, leading to drowsiness, dizziness, and impaired coordination.
    • Paroxetine may affect the metabolism of certain drugs processed by the liver (e.g., tamoxifen), so caution is needed when using such medications concurrently.
  • Food Interactions

    Following are the food interactions for Paroxetine 20mg Tablet:

    • Alcohol should be avoided while taking Paroxetine, as it can increase the risk of side effects such as dizziness, drowsiness, and difficulty concentrating.
    • Consuming large amounts of caffeine may increase the risk of nervousness, anxiety, and insomnia while taking Paroxetine.
    • Grapefruit and grapefruit juice may affect the metabolism of Paroxetine, leading to higher blood levels and an increased risk of side effects. It is advisable to limit grapefruit consumption during treatment.
  • Storage/Disposal

    Paroxetine 20mg Tablet should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep the medication in its original container and ensure it is tightly closed to prevent exposure to air and moisture. Do not store it in the bathroom or near the kitchen sink, as humidity can affect its effectiveness. Keep it out of reach of children and pets. If the medication is no longer needed or has expired, dispose of it properly. Do not flush it down the toilet or throw it in the trash. Instead, consult your pharmacist or local waste disposal guidelines for proper disposal methods to ensure safety and prevent environmental harm.

  • Quick Tips, if any

    Following are the quick tips for Paroxetine 20mg Tablet:

    • Take Paroxetine as prescribed by your healthcare provider for optimal results.
    • It is usually taken once daily, in the morning or evening, with or without food.
    • Do not suddenly stop taking Paroxetine without consulting your healthcare provider, as it may cause withdrawal symptoms.
    • If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Do not double up to make up for a missed dose.
    • Inform your healthcare provider of any other medications you are taking, as drug interactions can occur.
    • Regularly attend follow-up appointments to monitor your progress and adjust the dosage if necessary.

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