Rosuvastatin is a synthetic lipid-lowering agent. Its molecular weight is 1001.14. Rosuvastatin is an HMG Co-A reductase inhibitor. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Indicated for patients with primary hyperlipidemia and mixed dyslipidemia as an adjunct to diet to reduce elevated total-Cholesterol, LDL-C, non HDL-C, and TG levels and to increase HDL-C, in patients with hypertriglyceridemia as an adjunct to diet.
Ingredients
Rosuvastatin
Dosage Form
Tablet
Uses
High Cholesterol Diseases; Hyperlipidemia, Dyslipidemia, Hypertriglyceridemia.
Dosage
Dose must be taken according to the doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Adult dose: The dose range for rosuvastatin is 5 to 40 mg orally daily at night. The usual starting dose is 10-20mg at night. Dose could be adjusted within the interval of 2-4 weeks. Do not exceed 40mg a day. Child dose: For children of age 8 to <10 years; 5-10mg orally a day. For children of age 10-17 years; 5-20mg orally a day; dose could be adjusted at intervals of 4 weeks; do not exceed 20mg per day.
In case of Overdose
There is no specific treatment in the event of overdose. In the event of overdose, the patient should be treated symptomatically and supportive measures instituted as required.
Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
How To Use
Rosuvastatin can be administered as a single dose at night, with or without food. The tablet should be swallowed whole.
When Not to Use
Rosuvastatin should not be used in patients with a known hypersensitivity to any component of this product. Rosuvastatin should not be used in patients with active liver disease or with unexplained persistent elevations of serum liver enzymes.
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