PEDIET SYP 120ML

Silybum marianum, commonly known as milk thistle, contains the active compound silymarin, which is primarily composed of flavonoids including silybin, silydianin, and silychristin. These flavonoids exert their effects by primarily targeting the liver. The mechanism of action involves silymarin's ability to inhibit the binding of toxins to hepatic cell membrane receptors, thus protecting liver cells. It also stabilizes liver cell membranes, stimulates protein synthesis, and promotes the regeneration of liver tissue. Silymarin's antioxidant properties play a crucial role in scavenging free radicals, reducing oxidative stress, and supporting overall liver function. By modulating these processes, Silybum marianum helps in maintaining liver health and providing hepatoprotective effects.

Hepatoprotective (liver-protecting) agent

Suspension

The following are the uses of silybum marianum Syrup/Suspension:

• Used for liver protection and detoxification, supporting liver health and aiding in the treatment of liver diseases.
• Used for digestive health, helping to soothe digestive issues and promote healthy digestion.
• Used for antioxidant benefits, containing compounds that combat oxidative stress and reduce cell damage.
• Used for immune system support, boosting the body's natural defenses and promoting overall well-being.
• Used for anti-inflammatory effects, reducing inflammation and alleviating related symptoms.
• Used for skin health, potentially improving skin conditions and promoting a healthy complexion.
• Used for cholesterol management, aiding in maintaining healthy cholesterol levels.
• Used for potential cancer support, with some research suggesting its role in cancer prevention and treatment.

In the case of an overdose of Silybum marianum Syrup/Suspension, it is important to recognize the potential signs and symptoms. Common effects may include gastrointestinal distress, such as nausea, vomiting, and diarrhea. In more severe cases, liver toxicity can occur, leading to jaundice, abdominal pain, and potential liver damage. Prompt medical attention is necessary to manage these symptoms and prevent any long-term complications, especially if excessive amounts have been ingested.

In the case of a missed dose of Silybum Marianum Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It's important to maintain consistency with this medication, so try to set a routine to help you remember to take it at the same time each day.

To take Silybum Marianum syrup/suspension, shake the bottle well, measure the prescribed dose using a measuring cup or syringe, and administer it orally, following the dosage instructions provided by your healthcare professional, which may be once or twice daily, either with or without food, depending on your specific prescription.

Following are the conditions/situations when Silybum marianum Syrup/Suspension should not be taken:

• Not suitable for individuals with a known allergy to Silybum marianum (Milk Thistle) or any related plants from the Asteraceae/Compositae family.
• Avoid if you have a known allergy to any of the syrup/suspension's inactive ingredients.
• Contraindicated in patients with severe liver disease or liver failure.
• Not recommended for individuals with a history of hormone-sensitive cancers or conditions.
• Should not be used if you are taking certain medications that are broken down by the liver, as it may interfere with their metabolism.
• Avoid if you are pregnant or breastfeeding, as its safety is not well established.
• Not suitable for children without medical advice.

The side effects of Silybum marianum Syrup/Suspension may include:

• Gastrointestinal issues such as nausea, vomiting, diarrhea, or constipation.
• Headaches or migraines.
• Allergic reactions, including skin rashes, itching, or hives.
• Dizziness or lightheadedness.
• Fatigue or increased tiredness.
• Joint pain or muscle aches.
• Altered taste or loss of appetite.
• In rare cases, liver-related issues such as elevated liver enzymes.

Following are the precautions and warnings for Silybum marianum Syrup/Suspension:

• Allergic reactions may occur; discontinue use if any signs of allergy, such as rash or itching, are observed.
• Not recommended for individuals with liver disease or those taking medications that affect the liver, as it may impact liver function.
• May cause gastrointestinal discomfort, including nausea, vomiting, or diarrhea. Discontinue use if severe symptoms persist.
• Caution should be exercised in patients with a history of gallstones or gallbladder disease, as it may affect gallbladder function.
• Avoid excessive consumption, as high doses may lead to adverse effects.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Consult a healthcare professional before use if you have any underlying medical conditions or are taking other medications.

Following are the drug interactions for Silybum marianum Syrup/Suspension:

• Silybum marianum may decrease the effectiveness of medications metabolized by the liver, such as certain antidepressants (e.g., selective serotonin reuptake inhibitors) and antipsychotics.
• It can interact with blood thinners like warfarin, potentially altering the blood's ability to clot and increasing the risk of bleeding.
• When combined with diabetes medications, it may lower blood sugar levels, possibly leading to hypoglycemia.
• This supplement can affect the metabolism of medications processed by the liver, potentially increasing or decreasing their effectiveness.
• Silybum marianum may interact with certain anti-seizure medications, altering their blood levels.
• Caution is advised when using it with medications that are toxic to the liver, as it may enhance their effects.
• It may decrease the absorption of medications by affecting the gut, potentially reducing the effectiveness of some oral drugs.

Following are the food interactions for Silybum Marianum Syrup/Suspension:

• Avoid excessive caffeine intake, as it may interfere with the liver-protective effects of Silybum marianum.
• Grapefruit and grapefruit juice should be consumed with caution as they can alter the metabolism of certain compounds in the liver, potentially affecting the herb's activity.
• Avoid alcohol consumption, as it may counteract the liver-supportive benefits of this herb and increase the risk of liver damage.
• High-fat meals might slightly delay the absorption of Silybum marianum, but it doesn't significantly impact its overall effectiveness.
• Garlic and onions, rich in sulfur compounds, can support the liver-detoxifying effects of Silybum marianum.
• Green leafy vegetables, high in antioxidants, can enhance the herb's protective effects against liver damage.
• Turmeric, a natural anti-inflammatory, can potentially boost the herb's ability to reduce liver inflammation.

Silybum marianum Syrup/Suspension should be stored in a cool, dry area at room temperature, ensuring protection from direct sunlight and moisture. Maintain the medication in its original container, sealed tightly to prevent contamination. Avoid storage in bathrooms or near heat-emitting appliances like stoves or radiators, as extreme temperatures can compromise the medication's integrity. Prior to use, verify the expiration date on the packaging, and properly dispose of any unused or expired syrup; refrain from flushing it or pouring it down the drain. Consult your pharmacist or healthcare provider for appropriate disposal practices. It is crucial to keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Silybum Marianum Syrup/Suspension:

• Consult a healthcare professional for dosage instructions tailored to your needs.
• Ensure you understand the prescribed dosage and duration of treatment.
• Shake the bottle well before each use to maintain consistency.
• Administer the syrup using the provided measuring device for accuracy.
• Take the syrup as directed, typically after meals for better tolerance.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Regularly monitor your progress and inform your doctor of any persistent side effects.