Pedrol Forte (250mg/5ml) 90ml Suspension

Cefpodoxime 250mg syrup/suspension acts by inhibiting the synthesis of the bacterial cell wall. It belongs to the cephalosporin class of antibiotics and specifically targets penicillin-binding proteins (PBPs) in susceptible bacteria. Cefpodoxime binds to these PBPs, which are essential for cross-linking peptidoglycan strands during cell wall formation, thereby disrupting bacterial cell wall synthesis. This interference weakens the cell wall, leading to cell lysis and eventual bacterial death. The medication's selective action against specific PBPs contributes to its effectiveness in treating a range of bacterial infections caused by susceptible organisms.

Cefpodoxime 250mg

Cephalosporin antibiotic.

Suspension

The following are the uses of Cefpodoxime 250mg Syrup/Suspension:

• Used for treating bacterial infections such as acute bacterial otitis media (ABOM) and pharyngitis.
• Used for effective relief from respiratory tract infections like pneumonia and bronchitis.
• Used to combat skin and soft tissue infections, providing healing and comfort.
• Used to treat urinary tract infections, ensuring a healthy urinary system.
• Used for managing acute bacterial exacerbations, offering respiratory support.
• Used for addressing bacterial sinusitis, promoting sinus health.
• Used as a powerful antibiotic, targeting various bacterial strains causing infections.

In the case of an overdose of Cefpodoxime 250mg Syrup/Suspension, the primary concern is the potential for gastrointestinal symptoms such as nausea, vomiting, and diarrhea. These symptoms may be more severe and prolonged compared to the usual side effects. Additionally, an overdose could lead to an increased risk of allergic reactions, including skin rashes, itching, and respiratory distress. It is crucial to seek medical advice promptly and provide the necessary information regarding the quantity ingested and the individual's medical history.

In the case of a missed dose of Cefpodoxime 250mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed with your medication regimen. It is crucial to maintain consistency in taking your medication as prescribed.

To take Cefpodoxime 250mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with the provided measuring cup or oral syringe, and administer the medication orally, following the dosing instructions provided by your healthcare professional, which may include taking it with or without food, typically twice a day, ensuring to complete the full course of medication as prescribed.

Following are the conditions when Cefpodoxime 250mg Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy to Cefpodoxime or other cephalosporin antibiotics.
• Not suitable for patients with a history of severe allergic reactions to penicillin.
• Contraindicated in patients with severe kidney disease or those undergoing dialysis.
• Should not be used to treat viral infections such as the common cold or flu.
• Not recommended for individuals with a history of gastrointestinal diseases, especially colitis.
• Avoid using if you have a history of seizures or conditions that increase the risk of seizures.
• Do not use if you have recently received or are scheduled to receive a live attenuated vaccine.

The side effects of Cefpodoxime 250mg Syrup/Suspension may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain
• Skin rash or itching
• Headache
• Dizziness
• Vaginal yeast infection (in females)
• Allergic reactions (rare)

Following are the precautions and warnings for Cefpodoxime 250mg Syrup/Suspension:

• This medication should not be used in individuals with a known allergy to Cefpodoxime or other cephalosporin antibiotics.
• Patients with a history of gastrointestinal issues, such as colitis, should exercise caution as it may exacerbate these conditions.
• Cefpodoxime may reduce the effectiveness of contraceptive pills; alternative birth control methods are recommended during treatment.
• Regular monitoring of kidney function is advised, especially in patients with pre-existing kidney problems.
• If you have a history of severe allergies or asthma, inform your doctor as this medication may trigger allergic reactions.
• Always complete the full course of treatment as prescribed, even if you feel better, to ensure the infection is fully treated.
• Store the syrup/suspension in a cool, dry place, and do not freeze it. Discard any unused medication after the prescribed duration.

Following are the drug interactions for Cefpodoxime 250mg Syrup/Suspension:

• Probenecid, a drug used to treat gout, can decrease the excretion of Cefpodoxime, leading to higher drug levels in the body.
• Antacids containing aluminum or magnesium can reduce the absorption of Cefpodoxime when taken simultaneously. Separate administration by at least 2 hours.
• Cefpodoxime may decrease the effectiveness of hormonal contraceptives, including birth control pills, patches, or rings. Consider using alternative contraception during treatment.
• The antibiotic Rifampicin can induce the metabolism of Cefpodoxime, reducing its effectiveness.
• The antidiabetic medication Metformin may have decreased absorption when taken with Cefpodoxime, potentially affecting blood sugar control.
• Cefpodoxime can potentially reduce the efficacy of live bacterial vaccines (e.g., typhoid vaccine). Avoid live vaccines during treatment and for at least 3 days after.
• Warfarin, a blood thinner, may have enhanced anticoagulant effects when used with Cefpodoxime, requiring close monitoring of blood clotting parameters.

Following are the food interactions for Cefpodoxime 250mg Syrup/Suspension:

• Cefpodoxime can be taken with or without food, but consuming it with food may help reduce potential gastrointestinal upset.
• Avoid grapefruit and grapefruit juice as they can interfere with the absorption of Cefpodoxime, potentially reducing its effectiveness.
• Alcohol consumption should be minimized or avoided as it may increase the risk of gastrointestinal side effects and liver-related issues.
• Dairy products like milk, yogurt, or cheese should be consumed separately from Cefpodoxime, as calcium can bind with the antibiotic and reduce its absorption.
• Antacids containing magnesium or aluminum may decrease the absorption of Cefpodoxime, so it's best to take them at different times.
• Vitamin and mineral supplements, especially those containing iron, zinc, or calcium, can interact with Cefpodoxime and reduce its effectiveness. Take them at separate times.
• Caffeine-rich beverages like coffee and tea may increase the elimination of Cefpodoxime from the body, so it's best to limit their consumption during treatment.
• No significant interaction with specific foods, but maintaining a balanced diet is essential for overall health during antibiotic treatment.

Cefpodoxime 250mg Syrup/Suspension should be stored in a controlled environment, specifically at room temperature (between 68°F and 77°F or 20°C and 25°C), ensuring it is kept away from excessive heat, moisture, or direct sunlight. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to freeze the medication or expose it to extreme temperatures. Always refer to the packaging for the expiration date, and if the syrup is no longer needed or has expired, do not dispose of it via household waste or wastewater. Instead, consult a healthcare professional or pharmacist for guidance on safe disposal practices to minimize any potential environmental impact. Keep this medication securely stored, out of children's reach, to prevent accidental consumption.

Following are the quick tips for Cefpodoxime 250mg Syrup/Suspension:

• Consult a doctor for the right dosage and duration based on your medical condition.
• Administer the prescribed dose using the measuring cup or syringe provided.
• Ensure the entire dose is taken; do not split or crush the tablet.
• Store the syrup/suspension in a cool, dry place, away from direct sunlight and moisture.
• Do not freeze the medication, and keep it at room temperature.
• Regularly clean the measuring device to maintain hygiene.
• Stay hydrated while taking this medication to prevent kidney stones.
• Complete the full course of medication, even if you feel better, to ensure infection clearance.