Pedrol Total (120/1mg) 60ml Oral Suspension

Chlorpheniramine, an antihistamine in the syrup, works by blocking H1-receptor sites, preventing histamine from binding and leading to a reduction in allergic symptoms. Paracetamol, the other active ingredient, has analgesic and antipyretic properties, although its exact mechanism of action is not fully understood. It is believed to work by inhibiting the synthesis of prostaglandins, which are involved in pain and inflammation pathways, thereby providing relief from pain and reducing fever.

Chlorpheniramine, Paracetamol 120mg

Antihistamine, Analgesic

Suspension

The following are the uses of Chlorpheniramine, Paracetamol 120mg Syrup/Suspension:

• Used for relieving symptoms of allergies such as runny nose, sneezing, and itchy eyes.
• Used to reduce mild to moderate pain, such as headaches, toothaches, and muscle aches.
• Used for lowering fever and managing pain after vaccinations.
• Used to treat symptoms of the common cold and flu, including sore throat and body aches.
• Used for managing pain and discomfort associated with mild arthritis.
• Used to provide temporary relief from minor aches and pains in children and infants.
• Used as an antipyretic to break a fever and reduce discomfort.

In the case of an overdose of Chlorpheniramine and Paracetamol 120mg syrup/suspension, the severity of symptoms can vary based on the amount ingested. Common signs may include nausea, vomiting, and drowsiness. More serious effects can impact the liver and kidneys, potentially leading to acute liver or kidney failure. Prompt medical intervention is necessary to manage these symptoms effectively and minimize the risk of long-term complications.

In the case of a missed dose of Chlorpheniramine and Paracetamol 120mg Syrup/Suspension, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is important to maintain a consistent dosing routine, but if you miss a dose, consult your healthcare provider for further guidance if needed.

To administer Chlorpheniramine, Paracetamol 120mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and give it orally, following the dosage instructions provided by your healthcare professional, which may be taken with or without food as directed.

Following are the conditions or circumstances when Chlorpheniramine, Paracetamol 120mg Syrup/Suspension should not be used:

• Avoid using in patients with known allergies to Chlorpheniramine, Paracetamol, or any of the excipients in the syrup/suspension.
• Not recommended for individuals with severe liver or kidney disease.
• Should not be administered to patients with a history of gastrointestinal obstruction or severe constipation.
• Contraindicated in patients with a history of asthma, especially those with asthma related to aspirin sensitivity.
• Avoid using in individuals with a history of seizures or epilepsy.
• Not suitable for patients with narrow-angle glaucoma.
• Should not be given to infants or young children without medical advice.
• Contraindicated in patients with a known blood disorder or those taking medications that affect blood clotting.

The side effects of Chlorpheniramine, Paracetamol 120mg Syrup/Suspension may include:

• Drowsiness or sleepiness
• Dry mouth
• Nausea and vomiting
• Constipation or diarrhea
• Loss of appetite
• Blurred vision
• Restlessness or nervousness
• Difficulty in urination

Following are the precautions and warnings for Chlorpheniramine, Paracetamol 120mg Syrup/Suspension:

• This medication should not be used in patients with a known allergy to chlorpheniramine, paracetamol, or any other ingredients in the syrup.
• Patients with liver or kidney disease should use this medication with caution and under medical supervision as it may require dosage adjustments.
• Avoid alcohol consumption while taking this medication as it can increase the risk of liver damage.
• Do not exceed the recommended dosage, as it may lead to severe liver or kidney damage.
• This medication may cause drowsiness or dizziness; avoid driving or operating heavy machinery until you know how this medicine affects you.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks to the fetus or infant.
• Keep this medication out of reach of children. In case of accidental ingestion, seek immediate medical attention.

Following are the drug interactions for Chlorpheniramine, Paracetamol 120mg Syrup/Suspension:

• Alcohol may increase the risk of drowsiness and dizziness when taken with Chlorpheniramine.
• It may interact with other central nervous system depressants, such as opioids or benzodiazepines, enhancing their effects and potentially leading to respiratory depression.
• Paracetamol can affect the metabolism of certain medications like warfarin, increasing the risk of bleeding.
• Anticonvulsant drugs may have altered effectiveness when used with Chlorpheniramine.
• Monoamine oxidase inhibitors (MAOIs) should be avoided due to potential serious reactions.
• The effectiveness of Paracetamol may be reduced when taken with other pain medications like NSAIDs.
• Certain antidepressants and antipsychotics may interact with Chlorpheniramine, requiring dosage adjustments.

Following are the food interactions for Chlorpheniramine, Paracetamol 120mg Syrup/Suspension:

• Grapefruit and grapefruit juice should be avoided as they may alter the metabolism of Chlorpheniramine, potentially increasing its blood levels and prolonging its effects.
• Alcohol consumption should be minimized or avoided as it can increase the sedative effects of Chlorpheniramine, leading to enhanced drowsiness and reduced alertness.
• Paracetamol absorption can be affected by food, so it is best taken on an empty stomach to ensure faster and more effective absorption.
• Spicy foods should be consumed with caution as they may irritate the digestive system and potentially affect the absorption of Paracetamol.
• Caffeinated beverages may counteract the sedative effects of Chlorpheniramine, making it less effective for allergy symptoms.
• Dairy products may interfere with the absorption of Paracetamol, so it is advisable to separate milk and cheese intake from medication by a few hours.
• Fatty meals might delay the absorption of Paracetamol, so it is recommended to take the medication before or between meals.
• Always follow the advice of your healthcare provider regarding food interactions and medication timing.

Chlorpheniramine and Paracetamol 120mg Syrup/Suspension should be stored in a secure location, away from direct sunlight and moisture, at room temperature. Keep the bottle tightly sealed to maintain its integrity and effectiveness. Ensure the medication is stored in its original container to prevent contamination. Do not expose it to extreme temperatures or store it in the bathroom or kitchen, as heat and humidity can affect its quality. Dispose of any unused or expired syrup responsibly; do not pour it down the drain or flush it. Consult your pharmacist for guidance on proper disposal methods, and keep all medications out of the reach of children to prevent accidental consumption.

Following are the quick tips for Chlorpheniramine, Paracetamol 120mg Syrup/Suspension:

• Consult a healthcare professional for the correct dosage and duration of treatment.
• Ensure you understand the instructions and clarify any doubts before starting the medication.
• Take the syrup as directed, typically every 4-6 hours, but follow the prescribed schedule.
• Measure the dose accurately using the measuring cup provided or an oral syringe.
• Avoid taking more than the prescribed amount, as it may lead to adverse effects.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Keep a record of your medication schedule to ensure you don't miss any doses.