PERI SOLUTION

Calcium Chloride and Glucose injection works by replenishing and restoring depleted calcium and glucose levels in the body. Calcium Chloride acts as a calcium source, aiding in muscle contractions, nerve function, and blood coagulation. It helps maintain the integrity of cell membranes and supports various enzymatic processes. On the other hand, Glucose serves as a vital energy source, providing immediate fuel for cellular metabolism. When administered, Glucose is rapidly absorbed into the bloodstream, elevating blood glucose levels and supplying energy to tissues, particularly in hypoglycemic states. This combination helps correct electrolyte imbalances and supports the body's energy requirements, making it useful in various clinical settings.

Calcium Chloride 0.294 g, Glucose [ 1.5 %w/v]

Electrolyte supplement and Carbohydrate

Liquid

The following are the uses of Calcium Chloride 0.294 g, Glucose [ 1.5 %w/v] Liquid:

• Used as an intravenous (IV) solution to provide essential electrolytes, such as calcium and glucose, to the body.
• Used to treat or prevent low blood sugar levels (hypoglycemia) by replenishing glucose in the bloodstream.
• Calcium chloride is essential for maintaining normal heart function, muscle contraction, and nerve transmission, and it helps to regulate calcium levels in the blood.
• Used in certain medical conditions where both calcium and glucose are needed to support overall health, such as in cases of dehydration or certain metabolic conditions.
• It may be administered to individuals undergoing surgery or in emergency situations to stabilize electrolyte levels.

In the case of an overdose of Calcium Chloride 0.294 g and Glucose [1.5 %w/v] Liquid, symptoms may include extreme thirst, frequent urination, nausea, and muscle weakness. High glucose levels can lead to hyperglycemia, causing fatigue and increased thirst. Calcium chloride overdose can result in hypercalcemia, leading to muscle and bone pain. Immediate medical attention is required to manage symptoms and prevent potential complications.

In the case of a missed dose of Calcium Chloride 0.294 g, it is recommended to administer the missed dose as soon as possible, ensuring that the time between doses remains consistent. For Glucose [1.5% w/v] Liquid, if a dose is missed, it is generally safe to take the missed dose as soon as you remember, but if it's close to the time for the next dose, skip the missed dose and continue with the regular dosing schedule. It is advisable to consult a healthcare professional for specific guidance if you frequently miss doses.

To prepare the solution, dissolve 0.294 g of Calcium Chloride in water to create a 0.294 g/100 mL solution, then add 1.5 g of Glucose to make a 1.5% w/v Glucose solution, mixing well to ensure proper dissolution.

Following are the conditions or situations when Calcium Chloride 0.294 g and Glucose 1.5% w/v solution should not be used:

• Not recommended for individuals with a known hypersensitivity or allergy to calcium chloride or glucose.
• Contraindicated in patients with severe renal (kidney) impairment or uncontrolled renal failure.
• Should be avoided in patients with hypercalcemia (high blood calcium levels) or conditions that could lead to calcium overload.
• Not suitable for intravenous use in patients with thrombophlebitis (vein inflammation) or at the site of a recent venous thrombosis.
• Should be used with caution in patients with heart disease, especially those with digitalis toxicity or ventricular fibrillation.
• Glucose solutions should not be used in patients with known glucose intolerance or diabetes mellitus if blood glucose control is not closely monitored.
• Avoid in patients with fluid overload or conditions where fluid restriction is necessary.

The potential side effects of Calcium Chloride 0.294 g and Glucose [1.5 %w/v] Liquid may include:

• Irritation or pain at the injection site
• Redness or swelling
• Hypocalcemia (low calcium levels in the blood)
• Hyperglycemia (elevated blood sugar levels)
• Thirst and increased urination
• Nausea and vomiting
• Allergic reactions (such as rash, itching, or difficulty breathing)
• Electrolyte imbalances

Following are the precautions and warnings for Calcium Chloride 0.294 g, Glucose [1.5 %w/v] Liquid:

• This medication should be used with caution in patients with heart problems, as it may cause electrolyte imbalances and affect heart function.
• Patients with kidney issues should exercise caution, as calcium chloride can impact kidney function and may require dosage adjustments.
• Do not administer if the solution is cloudy or contains particles.
• Avoid rapid infusion, as it may lead to hypercalcaemia and potential cardiac complications.
• Monitor vital signs and assess for signs of fluid overload during administration.
• Elderly patients may be more susceptible to adverse effects; careful monitoring is advised.
• Diabetic patients should be aware that glucose is present in the solution and monitor their blood sugar levels accordingly.
• Always use under medical supervision and inform your doctor about any existing medical conditions.

Following are the drug interactions for Calcium Chloride 0.294 g, Glucose [1.5% w/v] Liquid:

• Loop diuretics (e.g., furosemide) may increase the risk of calcium-induced arrhythmias when used with calcium chloride.
• Calcium chloride may decrease the effectiveness of tetracycline antibiotics, so separate administration by at least 2 hours.
• Thiazide diuretics can increase calcium levels, leading to potential hypercalcemia when used with calcium chloride.
• Calcium chloride can reduce the absorption of oral iron supplements, and vice versa.
• Bisphosphonates may have reduced absorption when taken with calcium-containing solutions.
• Calcium chloride can decrease the cardiac effects of digitalis glycosides, requiring close monitoring.
• Anticonvulsants like phenytoin and phenobarbital may have decreased efficacy when used with calcium chloride.

Following are the food interactions for Calcium Chloride 0.294 g and Glucose [1.5 %w/v] Liquid:

• Calcium Chloride may interact with calcium-rich foods like dairy products, leafy greens, and fortified foods. Monitor calcium intake to prevent excessive calcium levels.
• Glucose is a simple sugar, and consuming it with sugary foods or beverages may rapidly increase blood sugar levels, especially in diabetics.
• Avoid excessive alcohol consumption as it can interfere with calcium absorption and disrupt glucose metabolism.
• High-fiber foods may reduce the absorption of Calcium Chloride. Space out fiber intake and medication for optimal absorption.
• Avoid grapefruit and grapefruit juice as they can affect glucose metabolism and potentially interact with glucose levels.
• Caffeine intake should be monitored as it can increase calcium excretion and affect calcium balance.
• Ensure adequate hydration when taking this medication, especially with high-salt diets, to maintain electrolyte balance.
• Avoid excessive vitamin D supplementation, as it can increase calcium absorption and lead to hypercalcemia.

Calcium Chloride 0.294 g and Glucose [1.5 %w/v] Liquid should be stored in a controlled environment, specifically a cool and dry place, ensuring it remains at room temperature. Protect the medication from direct sunlight and moisture to maintain its integrity. Store it in its original container, tightly sealed, to prevent contamination. Avoid storage in high-temperature areas like bathrooms or near heat sources, as temperature fluctuations can impact the medication's effectiveness. Dispose of any unused or expired liquid responsibly; do not dispose of it in sinks or toilets. Consult a pharmacist or healthcare professional for guidance on appropriate disposal methods. Keep the medication securely stored, away from children, to prevent accidental consumption.

Following are the quick tips for Calcium Chloride 0.294 g and Glucose [1.5 %w/v] Liquid:

• Consult a healthcare professional for dosage instructions based on your specific needs.
• Ensure the solution is properly mixed before administration.
• Administer the solution as directed, typically orally or as prescribed.
• Store the product at room temperature, away from direct sunlight.
• Always check the expiry date before use.
• Do not use if the solution is discolored or contains particles.
• Contact a healthcare provider immediately if any adverse effects occur.
• Keep a record of your dosage and any observed effects for future reference.