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  • Generic Name


Product Information

  • Description

    Permethrin is an insecticide that interacts with multiple mechanisms in the insect nervous system, leading to paralysis and death. It blocks voltage-gated sodium channels on neuronal cell membranes, preventing the generation and propagation of nerve impulses, resulting in impaired nerve signaling. Additionally, permethrin binds to the acethylcholine esterase (AChE) enzyme, inhibiting its activity which causes a buildup of the neurotransmitter acetylcholine, leading to overstimulation of the nervous system. Furthermore, its affinity for the gamma-aminobutyric acid (GABA) receptor causes disruption in the regulation of neuronal excitability, resulting in overactivity in the nervous system. These various modes of action make permethrin a potent and effective pesticide for targeting insects.

  • Ingredients


  • Drug Class


  • Dosage Form


  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Protect your clothing and footwear to prevent ticks and insects with insect repellent or treated clothing and footwear.
    • Use dedicated flea treatments to protect your cats and dogs from fleas, ticks, and insects.
    • There are various options for head lice treatment, including shampoos, conditioners, and creams. Some treatments need to be repeated several times to ensure elimination.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Normal dose • Apply permethrin cream from the pharmacy to the skin in a dose of between 1% and 0.5% depending on the severity of the infestation on a dry hairless area of skin that evening and leave on for 8 hours. Wash it off with soap and water afterwards. This can be repeated every 7 days if needed.
    • Scabies • Apply a 0.5% cream from the pharmacy to all skin from neck to soles of feet. Wash off after 8 hours.
    • Lice -1% cream is applied to the scalp and hair for 30 minutes then rinsed off. This is repeated after 9 gaps of up to 21 days.
  • In case of Overdose

    Permethrin is a neurotoxin that when overdosed can result in moderate to severe side effects that may require urgent medical intervention. Should you encounter any symptoms such as nausea, vomiting, dizziness or seizures after inadvertently overdosing on Permethrin, it is important to seek medical attention as soon as possible. A medical professional may decide to administer certain medications or provide supportive care to treat the effects of the overdose and monitor your vital signs. Note that the diagnosis and treatment of an overdose should only be performed by a qualified medical professional as it can be a serious condition that requires careful monitoring and management.

  • Missed Dose

    When it comes to missing a dose of permethrin, it is important to take it as soon as possible if you remember. However, if it is almost time for your next dose, it is advised to skip the missed dose and continue on your regular schedule. This is to ensure that you do not double up on doses, as this can lead to overdose and other health complications. If you have any questions or concerns about missing a dose of permethrin, it is crucial to consult with your doctor or nurse for personalized guidance and clarity.

  • How To Use

    Permethrin is a medication mostly used to treat scabies and lice. It is important to follow the instructions provided by your doctor or pharmacist to ensure the best results. Before applying Permethrin, it is recommended to read the patient information leaflet supplied with the medication to ensure you understand how to use it correctly each time you use it. It should be applied as a thin layer from the neck down to the soles of the feet, ensuring even coverage, especially behind the ears, neck, groin, and skin folds. If necessary, you can use a fine-toothed comb to spread the medication evenly on the scalp. After applying Permethrin, it is important to wash your hands carefully, avoiding contact with your eyes. Permethrin should not be used on open wounds or irritated skin, and you should not apply it near the eyes or mouth. It is also important to keep the area of skin where Permethrin was applied away from heat, open flames, or electrical appliances as it may be flammable. If you have any questions or concerns about using Permethrin, be sure to ask your healthcare provider.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Children under 2 years old without first speaking to a doctor. Permethrin products are considered safe for children over 2, but the active ingredient concentration may differ in products intended for young children.
    • If you are allergic to any of the ingredients. Allergens can cause mild symptoms such as rashes to more severe symptoms such as difficulty breathing.
    • While breastfeeding or pregnant without discussing with your doctor. Although there are low levels of Permethrin in breastmilk, potential effects on the fetus or baby are unknown.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Muscle tremors
    • Vomiting
    • Diarrhea
    • Dizziness
    • Nausea
    • Headaches
    • Rash
    • Fatigue
    • Difficulty breathing
    • Convulsions
    • Potential health hazards spanning from nervous system effects to liver toxicity.
  • Storage/Disposal

    Permethrin is a pesticide that needs to be properly stored to maintain its stability and effectiveness. To ensure this, it should be stored at a temperature range of 2°C (35°F) to 8°C (46°F). For extended periods, it should be refrigerated, but it should not be allowed to freeze. Ensure that Permethrin is stored in its original air-tight container and should be kept away from direct sunlight or intense artificial light. Due to its toxicity, it should be kept out of reach of children, pets, and livestock, and always refer to the product label for specific storage instructions. Following these guidelines ensures Permethrin's effectiveness and safety.

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