PERSANTIN 100MG TAB

Dipyridamole 100MG Tablet primarily exerts its therapeutic effects through several mechanisms of action. It acts as a phosphodiesterase inhibitor, which means it blocks the activity of phosphodiesterase enzymes, leading to increased levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in platelets and blood vessels. This elevation in cAMP and cGMP causes platelet inhibition, resulting in reduced platelet aggregation and adhesion, thereby preventing excessive blood clot formation. Additionally, Dipyridamole relaxes blood vessels by enhancing the production of prostacyclin and nitric oxide, which contributes to improved blood flow and vasodilation. This mechanism is particularly important in conditions where enhanced blood flow is desired, such as in certain cardiovascular disorders.

Antiplatelet agent

Tablet

The following are the uses of Dipyridamole 100MG Tablet:

• Used for reducing the risk of blood clots after heart valve replacement surgery.
• Used to prevent blood clots and improve blood flow in patients with a history of stroke or transient ischemic attacks.
• Used to manage chronic coronary artery disease, helping to reduce chest pain and improve exercise tolerance.
• Used to prevent the formation of blood clots in patients with atrial fibrillation.
• Used in combination with anticoagulants to enhance blood thinning and reduce the risk of clotting.
• Used to diagnose and assess blood flow issues in the heart during stress tests.
• Used as a secondary option for patients unable to tolerate or unsuitable for other antiplatelet medications.

In the case of an overdose of Dipyridamole 100MG Tablets, symptoms may include severe headaches, dizziness, fainting, and in more severe cases, chest pain and difficulty breathing. It is important to recognize the signs of overdose and seek medical assistance promptly. Treatment for overdose may involve supportive care, such as monitoring vital signs and providing oxygen therapy, as well as addressing any specific symptoms that arise to ensure the patient's well-being. Prompt medical intervention is key to managing any adverse effects.

In the case of a missed dose of Dipyridamole 100MG Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for advice on how to get back on track with your medication regimen.

To take Dipyridamole 100MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, and continue taking it as directed even if you feel well.

Following are the conditions/situations when Dipyridamole 100MG Tablet should not be used:

• Should not be used in patients with a known allergy to Dipyridamole or any of its components.
• Contraindicated in individuals with severe liver or kidney disease.
• Not recommended for patients with recent heart attack or unstable angina.
• Avoid using in individuals with severe low blood pressure.
• Should not be used during an acute asthma attack.
• Contraindicated in patients with coronary artery spasm.

The side effects of Dipyridamole 100MG Tablet may include:

• Headache
• Dizziness
• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Chest pain
• Flushing (warmth and redness in the face)
• Allergic reactions (skin rash, itching)

Following are the precautions and warnings for Dipyridamole 100MG Tablet:

• Do not use this medication if you are allergic to Dipyridamole or any of its inactive ingredients.
• Patients with severe liver or kidney disease should use this medication with caution as it is primarily metabolized in the liver and excreted by the kidneys.
• Dipyridamole may cause dizziness or lightheadedness, so caution is advised when performing activities that require alertness, such as driving or operating heavy machinery.
• Inform your doctor if you have a history of heart disease, low blood pressure, or recent heart attack as this medication can affect heart rate and blood pressure.
• This medication may increase the risk of bleeding, so inform your doctor if you have a bleeding disorder or are taking blood-thinning medications.
• Pregnant and breastfeeding women should consult their healthcare provider before taking Dipyridamole, as its safety during pregnancy and breastfeeding is not fully established.
• Avoid alcohol consumption while taking this medication as it may intensify side effects.
• If you experience chest pain, irregular heartbeat, or severe headache, seek immediate medical attention.

Following are the drug interactions for Dipyridamole 100MG Tablet:

• Aspirin and other antiplatelet medications may enhance the antiplatelet effect, increasing the risk of bleeding.
• Non-steroidal anti-inflammatory drugs (NSAIDs) can reduce the bioavailability of Dipyridamole, potentially decreasing its effectiveness.
• Warfarin and other oral anticoagulants may have additive effects, requiring careful monitoring of coagulation parameters.
• Theophylline blood levels may increase, leading to potential toxicity.
• Phenytoin and Carbamazepine can reduce plasma concentrations of Dipyridamole, possibly reducing its therapeutic effect.
• Cimetidine may increase plasma concentrations of Dipyridamole, potentially requiring dose adjustments.
• Propranolol and other beta-blockers can have additive effects on heart rate and blood pressure.

Following are the food interactions for Dipyridamole 100MG Tablet:

• Avoid consuming alcohol as it may increase the risk of bleeding and interfere with the medication's effectiveness.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the absorption of Dipyridamole, potentially leading to increased blood levels and side effects.
• Caffeine-rich foods and beverages, like coffee, tea, and energy drinks, should be limited as they may interact with Dipyridamole and impact its blood-thinning effect.
• Foods high in tyramine, such as aged cheeses, cured meats, and fermented foods, should be avoided to prevent potential blood pressure spikes.
• Avoid high-fat meals as they may alter the absorption of Dipyridamole, affecting its therapeutic effect.
• Avoid natural blood-thinning foods like garlic, ginger, and certain herbal supplements, as they may enhance the medication's effect and increase bleeding risks.
• Consume a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support overall health while taking Dipyridamole.
• Always consult your healthcare provider for personalized dietary advice when taking this medication.

Dipyridamole 100MG Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in hot or humid environments like bathrooms or near kitchen appliances. Proper disposal of unused or expired medication is essential; do not flush or pour them down the drain. Consult your pharmacist for safe disposal practices, and always keep the medication out of children's reach to prevent accidental consumption. Remember to adhere to these storage and disposal guidelines to maintain the effectiveness and safety of Dipyridamole 100MG Tablets.

Following are the quick tips for Dipyridamole 100MG Tablet:

• Take the tablet as directed by your doctor, usually 4 times a day.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent dosing schedule to ensure the best effect.
• Avoid grapefruit and grapefruit juice while taking this medication.
• Inform your doctor if you have any upcoming surgeries.
• Do not stop taking the medication without consulting your healthcare provider.
• Store the tablets at room temperature away from moisture and heat.