PEYONA SOLUTION AMP

Caffeine citrate exerts its effects primarily by antagonizing adenosine receptors in the central nervous system. It binds to and blocks A1 and A2A adenosine receptors, leading to increased neuronal activity and reduced inhibition. This mechanism results in heightened alertness, wakefulness, and stimulation of the respiratory center in the brain. Caffeine also promotes the release of neurotransmitters such as dopamine and norepinephrine, contributing to increased neuronal firing and enhanced cognitive function. By inhibiting phosphodiesterase, caffeine raises intracellular cyclic AMP levels, which further contributes to its stimulatory effects. Additionally, caffeine may enhance the release of excitatory neurotransmitters like glutamate and acetylcholine, while inhibiting inhibitory neurotransmitters like GABA, thereby promoting overall neuronal excitability.

caffeine citrate

Xanthine derivative

Liquid

The following are the uses of caffeine citrate Liquid:

• Used for treating breathing problems in premature babies
• Used to improve lung function and reduce apnea (temporary cessation of breathing)
• Used for stimulating the central nervous system
• Used for increasing alertness and reducing fatigue
• Used in the treatment of headaches and migraines
• Used to enhance athletic performance and improve endurance
• Used for enhancing cognitive function and concentration
• Used to treat post-dural puncture headaches

In the case of an overdose of caffeine citrate liquid, individuals may experience symptoms such as rapid breathing, restlessness, and increased heart rate. The severity of these symptoms can vary depending on the amount ingested. It is important to recognize the signs of caffeine overdose, which may include nausea, vomiting, and in severe cases, seizures or irregular heart rhythms. Prompt medical intervention is necessary to manage these symptoms and prevent potential complications. Seeking medical advice is crucial to ensure appropriate treatment and support.

In the case of a missed dose of caffeine citrate liquid, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust the dosing schedule to ensure the best therapeutic outcome.

To administer caffeine citrate liquid, gently shake the bottle, measure the prescribed dose with an oral syringe, and administer it directly into the child's mouth, ensuring accuracy and following the healthcare provider's instructions for dosage and frequency.

Here are the situations or conditions when caffeine citrate liquid should not be used:

• Should not be given to infants who are less than 34 weeks old at birth.
• Contraindicated for infants with a known allergy or sensitivity to caffeine or citrate.
• Not recommended for infants with seizures or a history of seizures.
• Should not be administered to infants with heart problems or irregular heart rhythms.
• Contraindicated in infants with severe respiratory distress syndrome.
• Avoid use in infants with gastrointestinal bleeding or perforation.
• Not suitable for infants with a history of necrotizing enterocolitis.
• Should not be given to infants with a family history of sudden infant death syndrome (SIDS).
• Avoid use in infants with a known metabolic disorder.
• Contraindicated during periods of severe apnea (breathing pauses) or bradycardia (slow heart rate).

The side effects of caffeine citrate liquid may include:

• Restlessness and irritability
• Increased heart rate or palpitations
• Insomnia or difficulty sleeping
• Nervousness and anxiety
• Nausea or upset stomach
• Tremors or shaking
• Headaches
• Increased urination

Following are the precautions and warnings:

• Caffeine Citrate Liquid should be used with caution in infants and neonates, especially those with a history of seizures, heart conditions, or respiratory problems.
• It should be administered only under medical supervision and after a thorough medical evaluation.
• This medication must be given in precise doses as prescribed; overdosing can lead to serious side effects and toxicity.
• Caffeine Citrate Liquid should not be used for prolonged periods without medical advice, as it may lead to dependence and withdrawal symptoms upon discontinuation.
• Patients with liver or kidney disease may require adjusted doses and should be monitored closely.
• Avoid using this medication if there is a known sensitivity or allergy to caffeine or citrate.
• This medication may interact with other drugs, so it is crucial to inform healthcare professionals about all medications currently being taken.

Following are the drug interactions for caffeine citrate Liquid:

• Caffeine can increase the elimination of lithium, potentially reducing its effectiveness.
• It may decrease the sedative effects of benzodiazepines like diazepam and lorazepam.
• Caffeine can interact with certain antibiotics, such as ciprofloxacin and norfloxacin, potentially increasing their side effects.
• The effectiveness of stimulant medications (e.g., amphetamines) may be reduced when used with caffeine.
• Antacids may decrease the absorption of caffeine, reducing its effectiveness.
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen can delay the elimination of caffeine, leading to increased caffeine levels in the body.
• Caffeine may enhance the effects of other stimulants like ephedrine, increasing the risk of side effects.

Following are the food interactions for Caffeine Citrate Liquid:

• Avoid high-fat meals as they can decrease the absorption of caffeine, potentially reducing its effectiveness.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of caffeine, leading to increased caffeine levels in the body.
• Avoid excessive consumption of chocolate and energy drinks, as they contain caffeine and can lead to caffeine overdose when combined with the medication.
• Limit the intake of caffeinated beverages like coffee and tea, as they can add up to the total caffeine intake and potentially cause adverse effects.
• Avoid alcohol, as it can enhance the stimulant effects of caffeine and increase the risk of side effects like rapid heartbeat and insomnia.
• Consuming caffeine-containing foods like coffee ice cream or chocolate cake along with the medication should be monitored to prevent excessive caffeine intake.
• Herbal teas with stimulants like guarana or yerba mate should be used cautiously as they can increase the overall caffeine content.

Caffeine Citrate Liquid storage and disposal require specific attention to maintain its integrity. Store the liquid in a cool, dry area at room temperature, shielded from sunlight and moisture. Ensure the bottle is tightly sealed to prevent contamination. Avoid bathrooms or heat-prone areas like stoves, as temperature fluctuations can impact the medication. Always check the expiration date, and for disposal, do not flush or pour down drains. Consult a pharmacist for safe disposal methods, and keep the liquid away from children to prevent accidental consumption. Proper storage and disposal are crucial for safety and medication effectiveness.

Following are the quick tips for Caffeine Citrate Liquid:

• Always follow the dosage instructions provided by your doctor or pharmacist.
• Administer the liquid medication accurately using the provided measuring device.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Shake the bottle gently before each use to ensure the medication is well mixed.
• Check the expiration date regularly and discard if expired.
• Do not freeze the medication as it may affect its potency.
• Contact your healthcare provider if you notice any unusual side effects.