PHOLCODINE 60ML SYP (WILSON)

Pholcodine is an opioid cough suppressant, and its mechanism of action is primarily focused on suppressing the cough reflex. It acts centrally by binding to opioid receptors in the brainstem, particularly the cough center in the medulla oblongata. By interacting with these receptors, pholcodine reduces the sensitivity of the cough reflex, leading to a decrease in the frequency and intensity of coughing. This mechanism helps to provide relief from dry, unproductive coughing without affecting the respiratory drive or respiratory rate, making it useful for treating cough symptoms associated with various respiratory conditions.

Antitussive

Suspension

The following are the uses of Pholcodine Syrup/Suspension:

• Used for suppressing dry, irritating, and painful coughs
• Used to relieve symptoms of upper respiratory tract infections like the common cold and flu
• Used to treat coughs associated with allergies or environmental irritants
• Used to provide temporary relief from coughing fits
• Used to help reduce coughing and throat irritation caused by smoking or air pollution
• Used to soothe throat inflammation and ease coughing due to throat infections
• Used to manage coughs in patients with respiratory conditions like bronchitis or asthma

In the case of an overdose of Pholcodine Syrup/Suspension, it is crucial to recognize the signs, which may include severe drowsiness, difficulty breathing, and even loss of consciousness. Prompt action is vital; contact emergency medical services immediately. Quick response can help prevent severe consequences, as medical professionals can provide the necessary treatment to manage the overdose effectively and minimize potential harm.

In the case of a missed dose of Pholcodine Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you've missed multiple doses, contact your healthcare provider for advice on how to safely resume your medication regimen. It is crucial to maintain a consistent dosing routine for the medication's effectiveness.

To take Pholcodine Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and administer it orally, preferably after a meal, following the dosage instructions provided by your healthcare professional or as indicated on the medication label.

Here are the conditions or situations when Pholcodine Syrup/Suspension should not be used:

• Do not use if you have a known allergy or hypersensitivity to pholcodine or any of the excipients in the syrup/suspension.
• Contraindicated in patients with respiratory depression or severe breathing problems.
• Avoid use in individuals with acute asthma attacks or chronic obstructive pulmonary disease (COPD).
• Not suitable for patients with a history of bronchitis or chronic cough.
• Should not be given to children under 6 years of age.
• Do not use if you have a severe kidney or liver impairment.
• Contraindicated during breastfeeding as pholcodine can pass into breast milk.
• Avoid use in patients with a history of drug abuse or addiction.
• Not recommended for patients with a known or suspected gastrointestinal obstruction.

The side effects of Pholcodine Syrup/Suspension may include:

• Drowsiness or sleepiness
• Nausea and vomiting
• Dry mouth
• Constipation
• Impaired coordination and balance
• Allergic reactions (skin rash, itching, swelling)
• Difficulty in urination
• Confusion and disorientation, especially in elderly individuals

Following are the precautions and warnings for Pholcodine Syrup/Suspension:

• Pholcodine Syrup/Suspension should not be used for longer than the prescribed duration. Prolonged use can lead to respiratory depression and other serious side effects.
• Do not exceed the recommended dosage. Accidental overdose can result in severe respiratory issues, especially in children.
• Patients with a history of respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), should use this medication with caution and under medical supervision.
• It may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how this medication affects you.
• Alcohol consumption should be avoided as it can enhance the sedative effects of Pholcodine.
• This medication is not suitable for children under 6 years old.
• Consult your doctor if you have any liver or kidney problems before taking Pholcodine.
• Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.

Following are the drug interactions for Pholcodine Syrup/Suspension:

• Alcohol and other central nervous system depressants (e.g., benzodiazepines, opioids) may enhance respiratory depression and sedation.
• Pholcodine can interact with other medications that have anticholinergic properties, such as certain antidepressants and antihistamines, potentially leading to increased side effects.
• Monoamine oxidase inhibitors (MAOIs) should be avoided due to potential severe reactions, including increased risk of hypertensive crisis.
• It may interact with other medications that affect the gastrointestinal system, such as laxatives or antacids, altering their absorption.
• Caution is advised when taking Pholcodine with medications that affect the liver, as it is primarily metabolized by this organ.
• The effectiveness of some medications like antimuscarinics and certain antipsychotics may be reduced due to Pholcodine's anticholinergic effects.
• Pholcodine may increase the risk of side effects when taken with other medications that cause respiratory depression, such as strong opioids.

Following are the food interactions to consider with Pholcodine Syrup/Suspension:

• Grapefruit consumption should be avoided as it can increase the levels of Pholcodine in the blood, potentially leading to increased side effects.
• Alcohol intake is not recommended as it can enhance the sedative effects of Pholcodine, increasing the risk of dizziness and drowsiness.
• Hot beverages, such as coffee or tea, might cause the medication to become less effective, so it's best to avoid consuming them together.
• Dairy products may interfere with Pholcodine absorption, so it's advisable to separate them by a few hours.
• Spicy foods might irritate the throat and exacerbate the cough, making it wise to limit their consumption.
• Fatty meals can delay the absorption of Pholcodine, so it's best to allow some time between eating and taking the medication.
• It is generally recommended to take Pholcodine on an empty stomach to ensure optimal absorption.
• Always consult your healthcare provider for specific dietary guidelines tailored to your condition.

Pholcodine Syrup/Suspension should be stored at room temperature, away from sunlight and moisture, in its original container with the lid tightly secured. Avoid exposing it to extreme temperatures, such as storing it in the bathroom or near heat sources. Regularly check the expiration date, and dispose of any unused or expired medication responsibly. Do not dispose of it via toilet or drain; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication locked away from children to prevent accidental consumption.

Following are the quick tips for Pholcodine Syrup/Suspension:

• Administer the correct dose using an accurate measuring device.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Do not freeze the medication, as it may affect its potency.
• Check the expiration date before each use and discard if expired.
• Avoid sharing your medication with others, even if they have similar symptoms.
• Inform your doctor about any other medications you are taking to prevent potential interactions.
• Contact your healthcare provider if your symptoms worsen or persist after using the syrup.