Picoz (7.5mg/ml) 15ml Oral Drops

Sodium picosulfate is a stimulant laxative that primarily acts on the colon to promote bowel movements. Its mechanism of action involves stimulating intestinal motility by increasing intestinal secretions and accelerating colonic transit time. This compound acts as a prodrug, which is metabolized by intestinal bacteria to form the active metabolite, 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM), which activates intestinal mucosal receptors, leading to an increase in intestinal peristalsis and fluid secretion, ultimately resulting in bowel evacuation.

Laxative

Drop

The following are the uses of Sodium Picosulphate 5mg Drop:

• Used for short-term relief of constipation, softening stools, and making bowel movements more comfortable.
• Used to prepare the bowel for surgical procedures or medical examinations like colonoscopies.
• Used to prevent and treat constipation in bedridden patients or those with limited mobility.
• Used to promote bowel movement after childbirth or surgery to reduce the risk of complications.
• Used to alleviate constipation caused by certain medications or medical conditions.
• Used to maintain bowel regularity and prevent constipation in individuals with chronic constipation issues.
• Used to ensure bowel cleanliness before specific diagnostic procedures or surgeries.

Follow these dosage instructions:

• Adult Dosage

5-10 milligrams (mg) once a day. Your doctor will determine the length of the treatment.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

In the case of an overdose of Sodium Picosulphate 5mg Drops, symptoms may include severe gastrointestinal distress, such as nausea, vomiting, and diarrhea. The severity of these symptoms can vary based on the amount ingested. Prompt medical intervention is necessary to manage the immediate effects and prevent potential complications. Medical professionals should be contacted immediately to provide appropriate treatment and ensure the patient's safety.

In the case of a missed dose of Sodium Picosulphate 5mg Drops, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your medication routine. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To use Sodium Picosulphate 5mg Drops, fill the dropper with the prescribed number of drops, squeeze the liquid under your tongue, and hold it there for at least 30 seconds before swallowing, following the dosage instructions provided by your healthcare professional.

Here are the conditions or situations when Sodium Picosulphate 5mg Drops should not be used:

• Not recommended for individuals with a known allergy to Sodium Picosulphate or any of its constituents.
• Should not be administered to children under 2 years of age.
• Contraindicated in patients with gastrointestinal obstructions, including severe constipation, intestinal blockage, or suspected bowel obstruction.
• Avoid using in patients with severe dehydration or electrolyte imbalances.
• Not suitable for individuals with a history of hypersensitivity reactions to laxatives.
• Should not be used in patients with undiagnosed abdominal symptoms or acute abdominal pain.
• Contraindicated during an acute attack of inflammatory bowel disease.

The side effects of Sodium Picosulphate 5mg Drops may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or cramps
• Dizziness
• Fatigue and weakness
• Electrolyte imbalance (low potassium levels)
• Skin rashes or itching
• In rare cases, allergic reactions may occur.

Here are the precautions and warnings for Sodium Picosulphate 5mg Drops:

• Do not use if you are allergic to Sodium Picosulphate or any other components in the drops.
• Patients with kidney or liver problems should use with caution and under medical supervision as dosage adjustments may be necessary.
• Avoid alcohol consumption while using this medication as it may increase the risk of dizziness and drowsiness.
• This medication may cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
• Not recommended for children under 12 years of age unless prescribed by a doctor.
• Elderly patients may be more sensitive to the effects of this medication, so dosage adjustments may be required.
• Consult your doctor if you have a history of gastrointestinal diseases before using this medication.
• Pregnant and breastfeeding women should consult their healthcare provider for advice before taking this medication.

Following are the drug interactions for Sodium Picosulphate 5mg Drop:

• May decrease the effectiveness of oral contraceptives and hormone replacement therapy due to induced diarrhea.
• Concomitant use with other laxatives can lead to excessive bowel cleansing, dehydration, and electrolyte imbalances.
• Potentially increases the absorption of digoxin, requiring careful monitoring of digoxin levels.
• May reduce the absorption of certain medications, such as antibiotics, due to the accelerated transit time in the gastrointestinal tract.
• Sodium Picosulphate can interact with diuretics, leading to increased risk of electrolyte disturbances, especially in individuals with kidney impairment.
• Drugs affecting gastrointestinal motility, such as opioids, may reduce the effectiveness of Sodium Picosulphate.
• Caution is advised when using with cardiac glycosides; close monitoring of serum levels is necessary.

Following are the food interactions for Sodium Picosulphate 5mg Drop:

• Avoid excessive salt intake, as Sodium Picosulfate may interact with high sodium levels in the body.
• Limit or avoid alcohol consumption as it can increase the risk of dehydration and electrolyte imbalance.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the drug's metabolism.
• Consume high-fiber foods like whole grains, fruits, and vegetables to promote bowel movement and prevent constipation.
• Stay well-hydrated by drinking plenty of fluids, especially water, to support the laxative effect.
• Avoid caffeine as it can have a diuretic effect and potentially worsen dehydration.
• Dairy products may be consumed in moderation, but some individuals might experience temporary lactose intolerance due to bowel preparation.

Sodium Picosulphate 5mg Drops should be stored in a controlled environment, maintaining a cool temperature between 20-25°C (68-77°F) and away from direct sunlight. This medication should be kept in its original packaging, ensuring the container is tightly sealed to prevent contamination and maintain its integrity. Avoid exposing the drops to extreme temperatures, including freezing or excessive heat, as this can impact their effectiveness. Always adhere to the expiration date on the packaging, and if the product has expired, do not use it and dispose of it safely. For proper disposal, consult a healthcare professional or pharmacist for guidance, and never pour the medication down the drain or flush it down the toilet. Keep the drops out of children's reach to prevent accidental ingestion.

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Following are the quick tips for Sodium Picosulphate 5mg Drop:

• Administer the drops as directed by your doctor or pharmacist.
• Check the dropper for accuracy before use.
• Place the drops under the tongue and hold for a few moments before swallowing.
• Avoid touching the dropper tip to ensure the medicine remains sterile.
• Store the drops at room temperature, away from direct sunlight and moisture.
• Do not use if the solution changes color or becomes cloudy.
• Consult your doctor if you have any concerns or experience unusual symptoms during treatment.