Pigmanil-K 15g Cream

Kojic acid primarily works by inhibiting the activity of tyrosinase, a crucial enzyme in the production of melanin. By interfering with tyrosinase, kojic acid reduces the formation of melanin pigments, leading to skin lightening and the fading of dark spots. On the other hand, glycolic acid, an alpha-hydroxy acid (AHA), functions by exfoliating the skin's surface. It achieves this by breaking down the bonds that hold dead skin cells together, promoting their removal. This exfoliation process not only enhances skin texture and smoothness but also allows for better penetration of other active ingredients, thereby increasing the overall efficacy of the cream.

Antioxidant, Alpha Hydroxy Acid.

Cream

The following are the uses of Kojic Acid, Glycolic Acid Cream:

• Used for reducing the appearance of dark spots, age spots, and hyperpigmentation.
• Used for improving overall skin tone and brightness.
• Used for exfoliating the skin's surface, removing dead skin cells, and promoting skin renewal.
• Used for enhancing skin texture, making it appear smoother and more radiant.
• Used for addressing uneven skin tone caused by sun damage or scarring.
• Used for its antioxidant properties, providing protection against environmental stressors.
• Used for diminishing the visibility of fine lines and wrinkles over time.
• Used for maintaining a clear and youthful complexion when used regularly.

In the case of an overdose of Kojic Acid or Glycolic Acid Cream, it is important to remain calm and take immediate action. Rinse the affected area thoroughly with water to dilute the concentration of the acid. Seek medical assistance promptly, and provide the healthcare professional with information about the product and the amount ingested or applied. They will guide you on the necessary steps to manage the overdose effectively.

In the case of a missed dose of Kojic Acid, apply the cream as soon as you remember, but if it's almost time for your next application, skip the missed dose and continue with your regular schedule. For Glycolic Acid Cream, if you forget to apply it, apply it as soon as you notice the missed dose, but avoid applying extra to make up for the missed application. It's important not to double the dose to catch up, as this may increase the risk of skin irritation. Consult your healthcare provider if you have any concerns about missed doses and maintaining a consistent skincare routine.

To use the Kojic Acid, Glycolic Acid Cream, gently apply a thin layer to the affected area of the skin once or twice daily, or as directed by your healthcare provider, after cleansing and drying the skin thoroughly.

Following are the conditions and situations when Kojic Acid and Glycolic Acid Cream should not be used:

• Avoid using on skin that is broken, irritated, or severely inflamed.
• Not suitable for individuals with a known allergy to Kojic Acid or Glycolic Acid, or any other related acids.
• Do not use on areas with open wounds or sores.
• Avoid contact with eyes, nose, and mouth.
• Discontinue use if you experience severe redness, itching, or burning sensation.
• Not recommended for children without medical advice.
• Should not be used on skin that is overly sensitive to sunlight or has a high risk of sunburn.
• Avoid using on skin that has recently undergone laser treatments, chemical peels, or other aggressive procedures.
• Do not use if you are pregnant or breastfeeding, unless advised by a healthcare professional.
• Do not cover the treated area with occlusive dressings or bandages.

The side effects of Kojic Acid, Glycolic Acid Cream may include:

• Skin irritation, redness, or itching at the application site.
• Dryness or peeling of the skin.
• Burning or stinging sensation.
• Increased sensitivity to sunlight (photosensitivity).
• Darkening or lightening of the skin in rare cases.
• Allergic reactions, such as rash, hives, or itching.
• Mild skin inflammation (dermatitis).
• Prolonged use may lead to skin thinning or increased skin sensitivity.

Following are the precautions and warnings for Kojic Acid, Glycolic Acid Cream:

• Avoid contact with eyes, mouth, and other mucous membranes. In case of accidental contact, rinse thoroughly with water.
• Perform a patch test on a small area of skin before applying the cream to a larger area to check for any allergic reactions.
• Do not use on broken or irritated skin, and discontinue use if irritation or redness occurs.
• Kojic acid may increase sun sensitivity, so limit sun exposure and use sunscreen when outdoors.
• Do not use this cream for prolonged periods without consulting a dermatologist.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.
• Consult a healthcare professional before using this cream if you are pregnant, breastfeeding, or have any underlying skin conditions.

Following are the drug interactions for Kojic Acid, Glycolic Acid Cream:

• Kojic acid may enhance the effects of other skin-lightening agents, such as hydroquinone, leading to increased skin sensitivity and irritation.
• Using Kojic acid with other exfoliating agents like retinoids or other alpha-hydroxy acids (AHAs) can cause excessive dryness and peeling.
• It can increase the skin's sensitivity to the sun, so caution is advised when using it with other photosensitizing medications.
• Glycolic acid can increase skin sensitivity, and concurrent use with other topical medications may cause further irritation.
• The cream's effectiveness may be reduced when used with other products containing high concentrations of fatty acids or oils.
• Avoid using other products with high pH levels, as they can neutralize the effects of glycolic acid.
• Medications that affect skin barrier function may increase the absorption of Kojic acid, potentially leading to increased side effects.

Following are the food interactions for Kojic Acid, Glycolic Acid Cream:

• Kojic Acid may interact with citrus fruits, especially when applied topically, as some citrus fruits contain high levels of acidity which can cause skin irritation or sensitivity.
• Avoid using Kojic Acid with foods containing Vitamin C (ascorbic acid), as it can reduce the effectiveness of Kojic Acid and may cause skin redness.
• Glycolic Acid can make your skin more sensitive to sunlight, so avoid foods that are high in photosensitizing compounds like St. John's Wort, celery, and citrus fruits.
• Alcohol-based foods or beverages should be avoided as they can cause dryness and irritation when used with Glycolic Acid.
• Avoid spicy foods as they can increase skin sensitivity and may cause a burning sensation when combined with these acids.
• Dairy products might interfere with the absorption of Kojic Acid when taken orally.
• Kojic Acid may react with soy-based foods, as soy contains isoflavones that can potentially affect skin pigmentation.
• It is generally advised to maintain a diet low in simple sugars and refined carbohydrates to support the effectiveness of Kojic Acid in skin lightening.

Kojic Acid, Glycolic Acid Cream should be stored in a cool and dry place, preferably at room temperature, ensuring it is not exposed to direct sunlight or moisture. Keep the cream securely sealed in its original container to maintain its integrity and prevent contamination. Avoid storing it in areas with temperature fluctuations like bathrooms or near heat sources. Always adhere to the expiration date on the packaging, and when disposing of the cream, do not flush it or pour it down the drain. Consult your pharmacist for guidance on appropriate disposal methods to minimize environmental impact. Keep the cream out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Kojic Acid, Glycolic Acid Cream:

• Apply a thin layer to affected areas as directed by your dermatologist.
• Use on clean, dry skin for best results.
• Avoid contact with eyes and mucous membranes.
• Wear sunscreen daily as Kojic Acid increases sun sensitivity.
• Store the cream in a cool, dry place away from direct sunlight.
• Discontinue use if irritation or redness occurs and consult your doctor.
• Do not use on broken or irritated skin.