Piravir (200mg) 20 Tablets

Favipiravir 200mg Tablet, chemically known as favipiravir, is a synthetic antiviral drug that primarily acts as a viral RNA-dependent RNA polymerase (RdRp) inhibitor. It selectively inhibits the RNA polymerase enzyme of certain RNA viruses, including influenza viruses and some RNA-based viral pathogens. Favipiravir is a prodrug that is metabolized in the body to its active form, favipiravir-ribofuranosyl-5'-triphosphate (favipiravir-RTP). This active metabolite mimics the natural substrate of viral RNA polymerase, competing for incorporation into the growing RNA chain. Once incorporated, favipiravir-RTP induces lethal mutagenesis, causing an increase in the frequency of mutations in the viral genome, which ultimately leads to the inhibition of viral replication and the cessation of viral proliferation. This mechanism of action makes favipiravir effective in disrupting the replication process of specific RNA viruses.

Favipiravir 200mg

Antiviral, RNA-dependent RNA polymerase inhibitor.

Tablet

The following are the uses of Favipiravir 200mg Tablet:

• Used for treating mild to moderate COVID-19 infections.
• Used to combat viral infections, particularly those caused by RNA viruses.
• Used to manage influenza, including pandemic flu strains.
• Used as an antiviral agent to inhibit viral replication.
• Used for patients with uncomplicated influenza symptoms for up to 48 hours.
• Used to potentially reduce viral load and improve symptoms in COVID-19 patients.
• Used as part of a comprehensive treatment plan for viral respiratory infections.

In the case of an overdose of Favipiravir 200mg Tablets, it is important to recognize the potential symptoms and seek medical assistance promptly. Overdose symptoms may include gastrointestinal issues such as nausea, vomiting, and diarrhea, as well as more severe reactions like difficulty breathing, rapid heartbeat, or seizures. If an overdose is suspected, it is crucial to contact a healthcare professional or a poison control center for guidance and to receive appropriate medical care as soon as possible. Timely intervention can help manage adverse effects and ensure the best possible outcome.

In the case of a missed dose of Favipiravir 200mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Do not double the dose to make up for a missed dose. If you have missed multiple doses, consult your healthcare provider for guidance on how to get back on track with your medication schedule. It is crucial to maintain a consistent dosing routine for the best therapeutic effect.

To take Favipiravir 200mg Tablet, swallow the tablet whole with water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken twice daily with or after food as directed by your doctor.

Here are the conditions or situations when Favipiravir 200mg Tablet should not be used:

• Not recommended for individuals with a known hypersensitivity or allergy to Favipiravir or any of its excipients.
• Contraindicated in pregnant women as it may cause harm to the fetus.
• Should not be used in breastfeeding mothers due to potential risks to the infant.
• Not suitable for patients with severe kidney impairment or end-stage renal disease.
• Avoid in patients with a history of severe liver disease or impaired liver function.
• Not recommended for individuals with a known deficiency of the enzyme 'Thymidine Kinase'.
• Should not be used in patients with a history of hypersensitivity to ribavirin, as it may cause cross-sensitivity.
• Contraindicated in patients with severe bleeding disorders or those currently experiencing active bleeding.

The side effects of Favipiravir 200mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Fatigue and weakness
• Loss of appetite
• Altered liver function tests

Following are the precautions and warnings for Favipiravir 200mg Tablet:

• Not recommended for use in pregnant women due to potential risks to fetal development.
• Breastfeeding women should exercise caution, as it is unknown if Favipiravir passes into breast milk.
• Patients with severe kidney or liver impairment should use with caution and under medical supervision.
• Not suitable for children and adolescents under 18 years of age.
• Avoid if allergic to Favipiravir or any other components in the tablet.
• May cause dizziness and affect your ability to drive or operate machinery; caution is advised.
• Do not exceed the prescribed dosage, as it may lead to adverse effects and increased risk of viral resistance.

Following are the drug interactions for Favipiravir 200mg Tablet:

• It may interact with antacids containing aluminum, magnesium, or calcium, potentially reducing the absorption of Favipiravir. Consider separating the doses by at least 3 hours.
• Favipiravir can decrease the effectiveness of hormonal contraceptives, including birth control pills, patches, or rings. Alternative or additional non-hormonal methods of contraception are recommended.
• Co-administration with drugs that inhibit or induce the UGT1A1 enzyme, such as ritonavir or rifampicin, may affect Favipiravir metabolism and exposure. Close monitoring is advised.
• Caution is advised when using Favipiravir with other medications that affect kidney function, as this may increase the risk of kidney-related side effects.
• The drug may interact with immunosuppressants, potentially altering their effectiveness and increasing the risk of side effects. Regular monitoring is recommended.
• Favipiravir may increase the blood levels of certain antiviral medications, such as tenofovir, leading to increased side effects. Dose adjustments may be necessary.
• Concomitant use with other antiviral drugs may increase the risk of viral resistance, and close monitoring for treatment response is advised.

Following are the food interactions for Favipiravir 200mg Tablet:

• Avoid consuming grapefruit or grapefruit juice as it may increase the concentration of the drug in the body, potentially leading to increased side effects.
• Alcohol intake should be minimized or avoided as it may increase the risk of liver-related side effects and could also affect the overall effectiveness of the medication.
• High-fat meals can potentially delay the absorption of Favipiravir, so it is best to take the medication on an empty stomach for optimal absorption.
• Avoid caffeine-rich foods and beverages as they may interact with Favipiravir, potentially causing increased side effects such as insomnia and nervousness.
• Foods rich in vitamin C, like citrus fruits and broccoli, might influence the metabolism of Favipiravir, so it's advisable to consume them in moderation.
• Dairy products may interfere with the absorption of Favipiravir, so consider separating the medication and dairy intake by a few hours.
• Stay hydrated by drinking plenty of water to maintain fluid balance, especially if experiencing diarrhea as a side effect.
• A balanced diet with adequate protein and nutrients can support overall health and aid in managing potential side effects.

Favipiravir 200mg Tablets should be stored in a secure and dry location, away from direct sunlight, moisture, and heat. Maintain the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. It is crucial to store medications in a place that is inaccessible to children to prevent accidental consumption. Pay attention to the expiration date on the packaging, and refrain from using the tablets beyond this date. When disposing of unused or expired Favipiravir tablets, do not flush them down the toilet or drain. Instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods to minimize environmental impact.

Following are the quick tips for Favipiravir 200mg Tablet:

• Consult a doctor before use, especially if you have underlying health conditions.
• Start treatment early for better effectiveness.
• Take the tablet with or without food as directed by your doctor.
• Complete the full course of medication as prescribed.
• Stay well-hydrated while taking this medication.
• Regularly monitor your health and inform your doctor of any new symptoms.
• Store in a cool, dry place, away from direct sunlight.
• Do not share this medication with others; it is prescribed specifically for your condition.