Pitalo (1mg) 10 Tablets

Pitavastatin 1mg Tablet primarily works by inhibiting HMG-CoA reductase, a crucial enzyme in the liver responsible for cholesterol production. By blocking this enzyme, Pitavastatin significantly reduces the production of cholesterol, particularly low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol. This reduction in cholesterol synthesis results in a decrease in the overall levels of LDL cholesterol in the blood. Additionally, Pitavastatin may slightly increase high-density lipoprotein (HDL) or 'good' cholesterol, further contributing to its lipid-lowering effect. The net result is a more balanced cholesterol profile, which plays a vital role in preventing cardiovascular events, such as heart attacks and strokes, in individuals with dyslipidemia or high cholesterol levels.

HMG-CoA reductase inhibitor

Tablet

The following are the uses of Pitavastatin 1mg Tablet:

• Used for lowering high cholesterol levels, especially in individuals with a family history of high cholesterol.
• Used to reduce the risk of cardiovascular events like heart attacks and strokes.
• Used to manage dyslipidemia, a condition where there is an abnormal amount of lipids (fats) in the blood.
• Used for the treatment of hyperlipidemia, helping to decrease elevated levels of bad cholesterol (LDL) and triglycerides.
• Used to slow the progression of atherosclerosis, a condition where arteries become narrowed and hardened.
• Used in combination with lifestyle changes, such as diet and exercise, for comprehensive lipid management.
• Used to improve overall cardiovascular health and prevent long-term complications related to high cholesterol.

To be taken as per doctor's prescription

In the case of an overdose of Pitavastatin 1mg Tablets, it is important to recognize the potential symptoms and take appropriate action. Overdosing on this medication may lead to an increased risk of muscle-related side effects, including muscle pain, weakness, and in severe cases, rhabdomyolysis. If an overdose is suspected, immediate medical advice should be sought. Prompt medical evaluation and management are essential to ensure the best possible outcome and to prevent any potential long-term complications.

In the case of a missed dose of Pitavastatin 1mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra medication to make up for a missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To take Pitavastatin 1mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken once daily, with or without food, as directed.

Following are the conditions when Pitavastatin 1mg Tablet should not be used:

• Should not be used in individuals with a known allergy or hypersensitivity to Pitavastatin or any other statin medications.
• Contraindicated in patients with active liver disease or persistent elevations in liver enzymes.
• Not recommended for individuals with uncontrolled hypothyroidism.
• Should not be used in pregnant women as it may harm the unborn baby.
• Contraindicated in breastfeeding mothers as it can pass into breast milk.
• Not suitable for individuals with a history of muscle pain or weakness, especially if it was caused by previous statin use.
• Should be avoided in individuals with severe kidney disease or end-stage renal disease.
• Not recommended for people with a genetic condition called homozygous familial hypercholesterolemia.

The side effects of Pitavastatin 1mg Tablet may include:

• Muscle pain or weakness
• Joint pain
• Fatigue or tiredness
• Nausea and vomiting
• Diarrhea
• Constipation
• Increased blood sugar levels
• Liver enzyme abnormalities

Following are the precautions and warnings for Pitavastatin 1mg Tablet:

• Not recommended for individuals with active liver disease or unexplained elevated liver enzyme levels as it may cause further liver damage.
• Regular monitoring of liver function tests is necessary during treatment, and if abnormalities persist, the drug should be discontinued.
• Patients with a history of kidney problems should exercise caution, as the drug may need dosage adjustments in cases of renal impairment.
• Pitavastatin may increase blood sugar levels, so diabetic patients should monitor their blood glucose regularly and consult their doctor if adjustments in diabetes medications are needed.
• Patients who experience muscle pain, tenderness, or weakness should report it immediately, as it may indicate a serious side effect called myopathy.
• Grapefruit juice and alcohol should be avoided while taking this medication as they can affect the metabolism of Pitavastatin.
• Patients should inform their doctor about all medications they are taking, especially other cholesterol-lowering drugs, to avoid potential drug interactions.
• It should be used with caution in elderly patients as they may be more susceptible to side effects.

Following are the drug interactions for Pitavastatin 1mg Tablet:

• Pitavastatin may interact with other lipid-lowering medications like fenofibrate, leading to increased risk of muscle-related side effects.
• Concomitant use with cyclosporine can increase the risk of myopathy and rhabdomyolysis.
• It may elevate blood levels of digoxin, requiring close monitoring.
• Pitavastatin can increase the effects of warfarin and other anticoagulants, necessitating regular blood tests.
• Caution with immunosuppressants like tacrolimus due to potential drug interaction.
• Interactions with certain antifungal medications like ketoconazole may increase Pitavastatin levels.
• Combining with protease inhibitors, such as atazanavir, may require dose adjustments.

Following are the food interactions for Pitavastatin 1mg Tablet:

• Grapefruit and grapefruit juice should be avoided as they can increase the blood levels of Pitavastatin, leading to a higher risk of muscle-related side effects.
• Alcohol consumption should be limited or avoided as it can increase the risk of liver-related issues, especially when combined with Pitavastatin.
• High-fat meals may slightly increase the absorption of Pitavastatin, so it is advisable to maintain a consistent diet.
• Avoid excessive consumption of foods rich in vitamin K, like leafy greens, as Pitavastatin can affect blood clotting.
• Avoid or limit the use of cranberry juice as it may interfere with Pitavastatin's metabolism.
• Licorice may decrease the effectiveness of Pitavastatin, so it's best to avoid it.
• Inform your healthcare provider about any herbal supplements or vitamins you take, as some may interact with Pitavastatin.
• Always follow the dietary recommendations provided by your doctor or pharmacist for optimal results.

Pitavastatin 1mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to store them in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them down the toilet or pour them into drains. Consult your pharmacist for guidance on proper disposal methods, and always keep medications out of children's reach to prevent accidental consumption.

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Following are the quick tips for Pitavastatin 1mg Tablet:

• Take the tablet as directed by your doctor, typically once daily at night.
• Consume the tablet with a glass of water, preferably at the same time each day.
• Pitavastatin can be taken with or without food, but taking it with food may reduce the risk of stomach upset.
• Avoid drinking grapefruit juice or eating grapefruit as it may affect the medicine's effectiveness.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Do not crush, chew, or break the tablet; swallow it whole for proper absorption.
• Regularly monitor your cholesterol levels and liver function as advised by your healthcare provider.