Pitalo (4mg) 10 Tablets

Pitavastatin 4mg Tablet primarily works by inhibiting HMG-CoA reductase, a crucial enzyme in the liver responsible for cholesterol production. By blocking this enzyme, pitavastatin significantly reduces the production of cholesterol in the body. This inhibition leads to a decrease in low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol, as well as triglycerides, while increasing high-density lipoprotein (HDL) cholesterol, known as 'good' cholesterol. This mechanism is central to the medication's effectiveness in managing hyperlipidemia and reducing the risk of cardiovascular events.

HMG-CoA reductase inhibitor.

Tablet

The following are the uses of Pitavastatin 4mg Tablet:

• Used for lowering high cholesterol levels in individuals who struggle to control their cholesterol through diet and exercise alone.
• Used for reducing the risk of heart disease and stroke by managing cholesterol levels.
• Used for improving blood flow and preventing the formation of blockages in blood vessels.
• Used for managing atherosclerosis, a condition where cholesterol builds up in the arteries.
• Used for treating dyslipidemia, an imbalance of fats in the blood.
• Used for slowing down the progression of coronary heart disease.
• Used for long-term management of cholesterol to maintain heart health.

To be taken as per doctor's prescription

In the case of an overdose of Pitavastatin 4mg Tablets, individuals may experience symptoms such as muscle pain, weakness, and elevated liver enzymes. It is important to seek medical advice if you suspect an overdose, as prompt treatment can help manage these symptoms effectively. Depending on the severity, treatment may involve supportive care, monitoring of vital signs, and appropriate management of any complications that arise. Quick action can ensure a better outcome in such situations.

In the case of a missed dose of Pitavastatin 4mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice on how to safely adjust your medication schedule and ensure you receive the correct dosage going forward.

To take Pitavastatin 4mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken once daily in the evening.

Following are the conditions/situations when Pitavastatin 4mg Tablet should not be used:

• Should not be used in individuals with a known allergy or hypersensitivity to Pitavastatin or any other statin medications.
• Contraindicated in patients with active liver disease or persistent elevations in liver enzymes.
• Not recommended for individuals with uncontrolled hypothyroidism (underactive thyroid).
• Should not be used during pregnancy as it may harm the unborn baby.
• Contraindicated in breastfeeding women, as it can pass into breast milk and harm the nursing infant.
• Should be avoided in individuals with a history of muscle pain or weakness, as it may increase the risk of muscle-related side effects.
• Not suitable for individuals with a history of kidney disease or severe kidney impairment.
• Should not be used in patients with a history of rhabdomyolysis (a serious muscle condition).
• Contraindicated in individuals with a history of alcohol abuse or heavy drinking.

The side effects of Pitavastatin 4mg Tablet may include:

• Headache
• Muscle pain or weakness (myalgia)
• Nausea or vomiting
• Abdominal pain or discomfort
• Diarrhea or constipation
• Elevated liver enzyme levels
• Dizziness or lightheadedness
• Fatigue or tiredness
• Joint pain or stiffness
• Skin rash or itching
• Increased blood sugar levels
• Rare risk of rhabdomyolysis (severe muscle breakdown)
• Rare allergic reactions such as swelling or difficulty breathing

Following are the precautions and warnings for Pitavastatin 4mg Tablet:

• This medication is not recommended for individuals with known allergies or hypersensitivity to Pitavastatin or any other ingredients in the tablet.
• Regular monitoring of liver function is necessary, and the drug should be discontinued if there are any signs of liver injury.
• Pitavastatin may cause muscle pain or weakness; patients should report these symptoms immediately and seek medical attention.
• Caution is advised for patients with a history of kidney disease, as dosage adjustments might be required.
• It is important to inform your doctor about all medications you are taking, especially if you are using other cholesterol-lowering drugs or cyclosporine.
• Patients with a history of diabetes or hypothyroidism should have their blood sugar and thyroid function monitored regularly.
• Pitavastatin may cause harm to the fetus during pregnancy; effective birth control methods are recommended while taking this medication.
• Breastfeeding women should consult their healthcare provider as it is unknown if Pitavastatin passes into breast milk.

Following are the drug interactions for Pitavastatin 4mg Tablet:

• Gemfibrozil can increase the risk of muscle-related side effects when used with Pitavastatin, and dosage adjustments may be required.
• Pitavastatin may increase the blood levels of digoxin, necessitating close monitoring of digoxin levels.
• The use of Pitavastatin with ciclosporin may increase the risk of muscle problems, and their combination should be avoided.
• When combined with fibrates, such as fenofibrate, Pitavastatin may increase the risk of muscle-related adverse effects, and monitoring is recommended.
• Pitavastatin can increase the blood-thinning effects of warfarin, requiring regular monitoring of blood clotting time.
• Antifungal medications like ketoconazole and itraconazole can increase Pitavastatin levels, and dose adjustments may be necessary.
• Pitavastatin may increase the risk of muscle problems when taken with colchicine, and caution is advised.

Following are the food interactions to consider with Pitavastatin 4mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can significantly increase the levels of Pitavastatin in the blood, leading to potential liver damage and increased risk of muscle-related side effects.
• Alcohol intake should be limited or avoided as it can increase the risk of liver-related issues, especially when combined with Pitavastatin's potential impact on liver function.
• High-fat meals can slightly delay the absorption of Pitavastatin, but they do not significantly affect its overall effectiveness.
• It is advisable to maintain a consistent diet, especially regarding fat intake, to ensure stable absorption and effectiveness of the medication.
• Vitamin D supplements may be considered to mitigate the potential reduction in vitamin D levels caused by Pitavastatin.
• Avoid excessive consumption of licorice, as it may interact with Pitavastatin and affect blood pressure and potassium levels.
• Be cautious with high-dose vitamin B3 (niacin) supplements, as they can increase the risk of muscle-related side effects when combined with Pitavastatin.
• Always consult your healthcare provider for personalized dietary recommendations while taking Pitavastatin.

Pitavastatin 4mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid exposing the tablets to heat, including sources like heaters or radiators, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired medication carefully; do not flush or pour it down the drain. Consult your pharmacist for guidance on proper disposal methods, and always keep medicines out of children's reach to prevent accidental ingestion. This practice ensures the safe handling and disposal of Pitavastatin 4mg Tablets.

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Following are the quick tips for Pitavastatin 4mg Tablet:

• Consult your doctor for the right dosage and duration tailored to your health needs.
• Swallow the tablet whole; do not crush, chew, or break it for optimal absorption.
• Take the tablet at the same time each day to maintain consistent blood levels.
• Ensure you inform your doctor about your medical history and current medications.
• Avoid consuming large amounts of grapefruit or grapefruit juice while on this medication.
• Regularly monitor your blood sugar and cholesterol levels as advised by your doctor.
• Do not stop taking the medication without consulting your healthcare provider.