Plazo (200mg/5ml) 25ml Suspension

Azithromycin is a macrolide antibiotic that binds to the 50S ribosomal subunits of bacteria, inhibiting their protein synthesis. This binding prevents the movement of tRNA peptidyl molecules, causing the inhibition of peptide chain elongation and termination of protein synthesis. Due to its high concentrations in the respiratory, genital, and urinary tracts, azithromycin is effective in treating bacterial infections specifically in these areas. Mid-infrared spectroscopy has shown that azithromycin binds to the 50S subunit of ribosomes and interferes with the translocation step, crucial for peptide chain synthesis. It is considered a functional analog to erythromycin but has a broader spectrum against gram-negative organisms and improved resistance profile. The mechanism of action of azithromycin is based on its binding to the ribosome and the inhibition of the translocation of peptidyl-tRNA, a critical step in protein synthesis. It is this interference with protein synthesis that leads to the inhibition of bacterial growth and replication. Given its broad distribution and mechanism of action, azithromycin is effective in treating various infections caused by different types of bacteria.

Azithromycin 200mg/5ml

Macrolide

Syrup/Suspension

Azithromycin is utilized for the following therapeutic indications:

• Treatment of respiratory infections (e.g., pneumonia, bronchitis)
• Management of skin and soft tissue infections
• Treatment of sexually transmitted infections (e.g., chlamydia, gonorrhea)
• Treatment of otitis media (middle ear infections)
• Management of pharyngitis and tonsillitis
• Prophylaxis against endocarditis in high-risk patients
• Treatment of sinusitis
• Management of Mycobacterium avium complex (MAC) infections
• Efficacy against atypical pathogens (e.g., Mycoplasma, Chlamydia)

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Adult Tonsillitis- 500 mg once daily for 3 days.
• Acute Bronchitis- The usual dose is 500 mg once daily for 3 days.
• Pharyngitis and Sinusitis- 500 mg once daily for 3 days.
• Skin and Soft Tissue Infection- 500 mg once daily for 7 days.
• Ear infections/Otitis Media- 10 mg/kg once daily for 3 days not to exceed 500 mg.
• Cat Scratch Disease- 15 mg/kg once daily for 7 days not to exceed 900 mg.

Azithromycin is a medication that is used to treat a number of respiratory and intestinal infections. It is important to adhere to the recommended dosage to avoid experiencing an overdose of this medication. An overdose may result in an increased risk of side effects. Should an overdose occur, it is important to seek immediate medical attention. Symptoms of an overdose can include nausea, vomiting, diarrhea, abdominal discomfort, liver toxicity, liver failure, seizures, hearing loss, and impaired kidney function. In some cases, kidney injury may occur. Treatment for an azithromycin overdose may include pumping the stomach, inducing vomiting, or binding azithromycin in the gut to reduce absorption. Because azithromycin has a long half-life, symptoms may last for several days. It is important to note that not all symptoms may be experienced and that medical attention should still be sought if you feel like you have overdosed on this medication.

When it comes to missing a dose of Azithromycin, it's important to take the necessary steps to ensure your treatment isn't compromised. First, you must determine the amount of time that has passed since your missed dose. If it's close to the time for your next scheduled dose, it's generally recommended to skip the missed dose and return to your regular schedule. However, if it's been longer than usual since your last dose, you can take the missed dose immediately. It's crucial to avoid doubling up on doses if it's almost time for your next scheduled dose. Regardless of your decision, it's essential to seek professional advice from a medical expert to guide you personally on how to proceed. They will provide you with precise instructions based on the timing of your missed dose to optimize your treatment plan. Maintaining a consistent and complete treatment plan is vital for the effectiveness of Azithromycin. Ensure to adhere to the dosing schedule provided by your physician as closely as possible.

Before you take Azithromycin, it is important to discuss your medical history and all the medicines you are currently taking with your doctor. This includes prescription drugs, herbal remedies, and over-the-counter medications. Follow your doctor's instructions carefully and ask questions if you don't understand anything. Your doctor will determine the best dosage and duration of treatment for you. To take the tablets, swallow them whole with a full glass of water. If you are taking the suspension (liquid), use the provided measuring cup or spoon to ensure you measure out the correct dose. It is important to take Azithromycin around the same time every day. Continue taking it for the full duration of treatment, even if you feel better. To store Azithromycin, keep it at room temperature and away from direct light and heat. Avoid freezing. If you are pregnant or breastfeeding, talk to your doctor before taking Azithromycin. Some side effects may include diarrhea, nausea, abdominal pain, headache, fatigue, loss of appetite, rash, mood changes, and itchiness. If any of these side effects worsen or persist, let your doctor know. Contact your doctor immediately if you experience any unusual symptoms while taking Azithromycin.

Discerning instances where this medication may not be appropriate:

• You are allergic to Azithromycin or any of its ingredients. Antibiotics in this class include Omnicef, Zithromax, and Genric Zithromax. If you have had a allergic reaction to any similar antibiotics in the past, it is essential not to take it. Allergic reactions can be potentially life-threatening.
• You have certain kidney problems. Azithromycin is eliminated from the body by the kidneys, so if you have severe kidney disease or an abnormal kidney function, it may not be safe for you to take this medication. Your doctor may perform a test to check your kidney function before prescribing this medication to you.
• You have certain liver problems. Liver problems similar to kidney problems can make it dangerous to process this medication and increase the risk of side effects.
• You have a history of QT prolongation or certain heart problems. This medication can cause an abnormal heart rhythm, namely QT prolongation, which can be dangerous. If you have a history of QT prolongation or heart conditions such as irregular heartbeat, untreated sinus bradycardia, or cardiogenic shock, it is not recommended to take this medication due to the risk of developing serious heart problems.
• You are taking other medications that may interact with Azithromycin. There are several drugs that can interact with Azithromycin and increase the risk of side effects or decrease the effectiveness of the antibiotic. It is important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs.

Unraveling the side effects lurking behind this medications are as follows:

• Diarrhea
• Nausea
• Loss of appetite
• Thrush (a fungal infection of the mouth)
• Stomach cramps
• Irritability
• Aggression
• Anxiety

Azithromycin is a macrolide antibiotic used to treat various bacterial infections. To ensure the medication's effectiveness and safety, it is vital to follow the instructions provided by your pharmacist or healthcare provider on how to properly store it. Here is a detailed guide on how to do so: