Polypred (0.5%) 5ml Eye Drops

Prednisolone eye drops primarily exert their therapeutic effects through their anti-inflammatory properties. When administered to the eye, prednisolone, a synthetic corticosteroid, binds to glucocorticoid receptors on various ocular cells, including those in the cornea and conjunctiva. This binding triggers a cascade of intracellular events, leading to the suppression of multiple inflammatory mediators and the downregulation of genes involved in inflammation. Prednisolone inhibits the production of prostaglandins, leukotrienes, and other inflammatory cytokines, which are key players in the inflammatory response. By doing so, it reduces redness, swelling, and discomfort associated with ocular inflammation, providing relief and promoting healing in various eye conditions.

Corticosteroid eye drops.

Drop

The following are the uses of Prednisolone Drop:

• Used for reducing inflammation and treating eye conditions such as allergic conjunctivitis and uveitis.
• Used for managing eye injuries and post-surgical eye inflammation.
• Used for alleviating pain and discomfort caused by eye irritations.
• Used for treating corneal ulcers and preventing scarring.
• Used for controlling immune responses in the eye.
• Used for improving vision by reducing swelling and redness.
• Used for providing temporary relief from eye allergies.
• Used for promoting healing in various eye disorders.

In the case of an overdose of Prednisolone Drops, it is important to act swiftly. First, contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the severity of the overdose. The treatment may involve managing symptoms and ensuring the individual's vital signs are stable. Prompt action can help mitigate potential health risks associated with an overdose of this medication.

In the case of a missed dose of Prednisolone Eye Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule and ensure the medication's effectiveness.

To use Prednisolone eye drops, gently tilt your head back, pull down your lower eyelid to create a pocket, and hold the dropper above your eye; release one drop into the pocket, blink gently to allow the drop to spread, and maintain your head in a tilted position for a few seconds to prevent the medication from draining out.

Here are the situations when Prednisolone Eye Drops should not be used:

• Do not use if you have a known allergy or hypersensitivity to Prednisolone or any of the other ingredients in the eye drops.
• Contraindicated for individuals with untreated bacterial, viral, fungal, or parasitic infections in the eye.
• Should not be used if you have a history of glaucoma or raised intraocular pressure (IOP), unless closely monitored by an eye doctor.
• Not recommended for patients with recent ocular surgery or trauma, as it may delay healing.
• Avoid using these drops if you have a corneal ulcer or a herpes simplex virus (HSV) infection of the eye.
• Do not use if you have a fungal infection of the eye, such as candidiasis or aspergillosis.
• Not suitable for individuals with a history of ocular tuberculosis.

The side effects of Prednisolone Eye Drops may include:

• Stinging or burning sensation in the eyes
• Itchy or watery eyes
• Blurred vision
• Increased eye pressure (glaucoma)
• Cataract formation
• Eye discomfort or redness
• Dry eyes
• Increased risk of eye infections

Following are the precautions and warnings for Prednisolone Eye Drops:

• Do not use if you are allergic to any ingredients in the eye drops, including prednisolone acetate.
• Avoid wearing contact lenses while using these drops, as they may contain preservatives that can be absorbed by the lenses.
• Exercise caution if you have a history of eye infections, as the drops may mask or worsen existing infections.
• Do not exceed the prescribed dosage or duration of use, as prolonged use can lead to increased eye pressure and potential damage.
• Inform your doctor if you have any eye injuries, recent eye surgery, or a history of glaucoma before using these drops.
• Children and elderly patients should use these drops under medical supervision, as they may be more susceptible to side effects.
• If you experience persistent eye pain, changes in vision, or signs of infection, discontinue use and seek medical attention immediately.

Following are the drug interactions for Prednisolone Drop:

• Prednisolone may increase the risk of systemic side effects when used with other topical steroids or with oral/injectable corticosteroids.
• Concomitant use with nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of gastrointestinal bleeding.
• Antihypertensive medications may be less effective when used with Prednisolone due to its potential to elevate blood pressure.
• Blood glucose levels may be affected, so monitoring is required when used with antidiabetic medications.
• The risk of immunosuppression is increased when combined with other immunosuppressants.
• Live vaccines should be avoided as Prednisolone can reduce the body's immune response.
• Caution is advised with anticoagulants, as Prednisolone may alter their effects.

Following are the food interactions to consider with Prednisolone Eye Drops:

• Avoid consuming grapefruit and grapefruit juice as they may impact the effectiveness of Prednisolone by altering its metabolism.
• Alcohol consumption is generally not recommended with eye drops, as it may cause temporary blurriness or affect your ability to administer the drops accurately.
• Caffeine intake should be monitored, as Prednisolone can increase eye pressure in some cases, and caffeine may exacerbate this effect.
• While not a direct food interaction, remember that Prednisolone can cause increased appetite, so be mindful of your diet to maintain a healthy weight.
• No specific food restrictions are associated with Prednisolone eye drops, but maintaining a balanced diet is always advisable.
• Some herbal supplements, like St. John's Wort, may interact with Prednisolone; consult your doctor about any herbal remedies you use.
• Always follow your ophthalmologist's instructions regarding the use of eye drops and any dietary considerations.

Prednisolone eye drops should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be retained, keeping the medication sealed to maintain its integrity and prevent contamination. It is crucial not to expose the drops to extreme temperatures, such as those near heat sources or in bathrooms, as this can impact their effectiveness. Always adhere to the expiration date on the packaging, and for safe disposal, refrain from flushing or pouring the medication down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Keep the drops out of children's reach to prevent accidental ingestion.

Following are the quick tips for Prednisolone Drops:

• Wash your hands thoroughly before administering the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• Close your eyes gently and apply light pressure to the inner corner of your eye for a few minutes to minimize drainage.
• If you use other eye medications, wait at least 5 minutes before applying the next one to ensure proper absorption.
• Do not wear contact lenses while using these drops unless advised by your doctor.
• Store the eye drops at room temperature, away from direct sunlight and moisture.