Pregnol 20 Tablets

Allylestrenol primarily exerts its therapeutic effects through its actions on the endometrium and the maintenance of pregnancy. As a progestogen, allylestrenol binds to and activates progesterone receptors in target tissues, particularly in the uterus. This activation leads to changes in gene expression, resulting in the transformation of the endometrium to a secretory state, which is essential for establishing and maintaining pregnancy. The mechanism involves the regulation of various cellular processes, including the promotion of endometrial thickening, glandular development, and vascularization, creating a favorable environment for embryo implantation and subsequent fetal development. Allylestrenol's selective binding to progesterone receptors helps reduce the risk of miscarriage by stabilizing the endometrial lining and preventing contractions that could lead to premature delivery.

Allylestrenol

Progestogen

Tablet

The following are the uses of Allylestrenol Tablet:

• Used for treating threatened or habitual miscarriage.
• Used for managing bleeding during pregnancy.
• Used to prevent premature birth in women with a history of premature deliveries.
• Used for treating endometriosis-related pain and discomfort.
• Used to manage menstrual disorders and irregular cycles.
• Used for hormone replacement therapy in certain cases.
• Used for treating severe menstrual cramps and pelvic pain.
• Used to support pregnancy in specific high-risk cases.

In the case of an overdose of Allylestrenol Tablets, it is important to seek medical advice promptly. Symptoms of an overdose may include nausea, vomiting, and abdominal pain. The severity of these symptoms can vary depending on the amount ingested. If you suspect an overdose, contact a healthcare professional or a poison control center for guidance. They will provide specific instructions and treatment options based on the individual's condition.

In the case of a missed dose of Allylestrenol Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice on how to safely resume your treatment and adjust your dosing schedule. It is recommended to maintain a consistent routine to avoid missing doses in the future.

To take Allylestrenol Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your doctor or as directed on the prescription label, ensuring you complete the full course as prescribed.

The following are the circumstances under which Allylestrenol Tablet should not be administered:

• Contraindicated in individuals with a known hypersensitivity or allergy to Allylestrenol or any of its excipients.
• Not suitable for use during pregnancy as it may cause harm to the fetus.
• Avoid in patients with severe liver impairment or active liver disease, as it is primarily metabolized in the liver.
• Should not be used in patients with a history of thromboembolic disorders or active thrombophlebitis due to its potential to increase the risk of blood clots.
• Contraindicated in individuals with undiagnosed abnormal genital bleeding until the cause has been determined.
• Not recommended for individuals with breast cancer or a history of hormone-dependent tumors, as it is a progestogen.

The side effects of Allylestrenol Tablet may include:

• Changes in menstrual cycle (irregular periods)
• Breast tenderness or enlargement
• Weight gain
• Mood changes, including depression or mood swings
• Headaches or migraines
• Nausea and vomiting
• Skin reactions such as acne or rashes
• Increased risk of blood clots in rare cases

Following are the precautions and warnings for Allylestrenol Tablet:

• Allylestrenol should not be used by individuals with a known or suspected allergy to the drug or any of its components.
• It is crucial to inform your doctor about any pre-existing medical conditions, especially if you have a history of liver or kidney disease, as these conditions may require dosage adjustments.
• This medication may cause dizziness or drowsiness, so caution is advised when performing tasks that require mental alertness, such as driving or operating machinery.
• Alcohol consumption should be avoided or limited while taking Allylestrenol, as it may increase the risk of side effects.
• If you are pregnant or planning to become pregnant, consult your doctor before taking this medication, as it may have potential risks for the fetus.
• For breastfeeding women, Allylestrenol may pass into breast milk, so it is essential to discuss the potential risks and benefits with your healthcare provider.
• Do not exceed the prescribed dosage, as it may increase the likelihood of adverse effects.
• Keep this medication out of the reach of children and pets, and store it as directed on the packaging.

Following are the drug interactions for Allylestrenol Tablet:

• Alcohol consumption should be avoided as it may increase the risk of liver damage.
• Allylestrenol may decrease the effectiveness of oral contraceptives, requiring alternative birth control methods.
• It can enhance the effects of anticoagulants, necessitating monitoring for bleeding.
• May interact with anti-seizure medications, potentially requiring dosage adjustments.
• Caution is advised when using with other medications metabolized by the liver, as it may affect their blood levels.
• Barbiturates can reduce the effectiveness of allylestrenol, requiring close monitoring.
• The effects of corticosteroids may be altered when used with allylestrenol, necessitating dosage adjustments.

Following are the food interactions for Allylestrenol Tablet:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the liver enzymes, affecting the metabolism of the drug.
• Alcohol consumption should be limited as it may increase the risk of liver-related side effects and may also affect hormone levels.
• Avoid high-fat meals as they can delay the absorption of the medication, potentially reducing its effectiveness.
• Caffeine intake should be monitored as it may interact with the medication, leading to increased heart rate or blood pressure.
• Salt intake should be reduced as Allylestrenol can cause fluid retention, and a high-salt diet may exacerbate this effect.
• Avoid excessive consumption of Vitamin A-rich foods like liver, as high doses of Vitamin A can interact with the medication.
• Limit the intake of foods containing high levels of phytoestrogens, such as soy products, as they may have additive effects with the medication.
• Consult your doctor about any herbal supplements, especially St. John's Wort, as they may influence the drug's metabolism.

Allylestrenol Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Maintain a consistent room temperature, avoiding exposure to direct sunlight, excessive heat, or moisture, as these conditions can degrade the medication. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain its integrity and prevent contamination. Regularly check the expiration date, and do not use the medication if it has passed this date. When disposing of unused or expired tablets, do not flush them down the toilet or dispose of them in regular household waste. Instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the medication away from children and pets to prevent accidental ingestion.

Following are the quick tips for Allylestrenol Tablet:

• Take the tablet as directed by your doctor, typically with or after meals.
• Swallow the tablet whole without crushing or chewing for best results.
• Maintain a consistent daily routine for taking the medication.
• Avoid missing doses; if you miss a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Do not double the dose to make up for a missed one.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Consult your doctor if you experience any unusual symptoms or side effects while taking this medication.