PREGNYL 5000IU INJ

Chorionic Gonadotropin (hCG) exerts its effects by mimicking the actions of luteinizing hormone (LH) in the body. Upon administration, hCG binds to LH receptors on the target cells in the gonads, primarily the corpus luteum in females and Leydig cells in males. This binding triggers a signaling cascade that leads to increased production of steroid hormones, particularly progesterone in females and testosterone in males. The mechanism involves the stimulation of cholesterol transport and conversion within the gonadal cells, ultimately resulting in the synthesis and release of these hormones, which play crucial roles in various reproductive processes.

Chorionic Gonadotrophin

Gonadotropins

injection

The following are the uses of Chorionic Gonadotrophin injection:

• Used for stimulating ovulation in women with fertility issues.
• Used for treating delayed puberty in boys and girls.
• Used for addressing undescended testes in young males.
• Used for managing hypogonadism in men.
• Used for supporting sperm production in males with fertility concerns.
• Used for treating endometriosis-related infertility.
• Used for ovarian hyperstimulation in assisted reproductive techniques.
• Used for managing oligozoospermia (low sperm count).

In the case of an overdose of Chorionic Gonadotrophin injection, patients may experience symptoms such as nausea, vomiting, and abdominal pain. The severity of these symptoms can vary depending on the individual and the amount of medication ingested. If an overdose is suspected, it is important to seek medical advice promptly. Treatment may involve supportive care and monitoring of vital signs, as well as managing any specific symptoms that arise. Early intervention can help prevent potential complications.

In the case of a missed dose of Chorionic Gonadotrophin injection, it is important to consult your healthcare provider for specific instructions. Generally, if you miss a dose, administer the injection as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one. However, if you miss multiple doses, contact your doctor to determine the best course of action to ensure the treatment's effectiveness.

To administer the Chorionic Gonadotrophin injection, clean the injection site with an alcohol swab, insert the needle at a 45-degree angle, inject the prescribed dose subcutaneously or intramuscularly as directed by your healthcare provider, and gently press a cotton ball over the injection site after withdrawing the needle.

Here are the conditions or situations when Chorionic Gonadotrophin injection should not be used:

• Allergic reactions should not be administered to individuals with a known or suspected allergy to Chorionic Gonadotrophin or any of its excipients.
• Pregnancy contraindicated in pregnant women, especially during early pregnancy, as it may interfere with natural hormone levels.
• Ovarian cysts or enlargement not recommended for patients with ovarian cysts or ovarian enlargement unrelated to polycystic ovary syndrome (PCOS).
• Thyroid or adrenal dysfunction should be used with caution in individuals with uncontrolled thyroid or adrenal disorders.
• Pituitary gland disorders not suitable for patients with pituitary gland issues or tumors.
• Liver disease contraindicated in patients with severe liver impairment or active liver disease.
• Uterine bleeding should not be used in cases of undiagnosed vaginal bleeding or endometrial hyperplasia.

The side effects of Chorionic Gonadotrophin injection may include:

• Allergic reactions such as rash, itching, or hives.
• Swelling at the injection site.
• Ovarian hyperstimulation syndrome (OHSS), which can lead to abdominal pain, swelling, and nausea.
• Headaches and dizziness.
• Mood changes and irritability.
• Fatigue and restlessness.
• Mild breast tenderness.
• Increased risk of multiple pregnancies.

Following are the precautions and warnings for Chorionic Gonadotrophin injection:

• Allergic reactions may occur; patients with known allergies to hormones or other medications should inform their doctor.
• Not recommended for use in pregnant women, as it may cause ovarian hyperstimulation syndrome.
• Patients with thyroid or pituitary gland disorders should be monitored closely during treatment.
• May cause premature puberty in young children; use with caution and under medical supervision.
• Elderly patients may be more sensitive to the effects and side effects of the medication.
• May cause multiple pregnancies; patients should be aware of the potential risks.
• Discontinue use and seek medical attention if severe abdominal pain, shortness of breath, or severe headaches occur.

Following are the drug interactions for Chorionic Gonadotrophin injection:

• It may interact with clomiphene, a fertility medication, and alter its effectiveness.
• Concomitant use with gonadotropin-releasing hormone (GnRH) agonists can lead to ovarian hyperstimulation syndrome.
• Interactions with hormone therapies, such as estrogen or testosterone, can affect the desired hormonal balance.
• Certain antipsychotic medications may interfere with the action of Chorionic Gonadotrophin.
• Drugs that suppress the immune system, like corticosteroids, can impact the body's response to the injection.
• Combining with insulin or oral hypoglycemic agents may require dose adjustments due to potential changes in blood sugar levels.
• Caution is advised when using with other fertility treatments, as it may increase the risk of multiple pregnancies.

Following are the food interactions for Chorionic Gonadotrophin injection:

• Avoid excessive caffeine intake as it may interfere with hormone regulation and increase side effects like restlessness and insomnia.
• Limit or avoid alcohol consumption as it can interact with the injection, potentially increasing the risk of side effects and affecting hormone balance.
• Grapefruit and its juice should be consumed with caution as they can affect hormone metabolism and increase the levels of certain hormones in the body.
• Avoid high-fat meals before and after injection as fat can affect the absorption and distribution of the medication.
• Maintain a balanced diet rich in lean proteins, whole grains, fruits, and vegetables to support overall health during treatment.
• Avoid herbal supplements without medical advice as some herbs may interact with hormone therapies.
• Stay hydrated by drinking adequate water to support overall health and aid in the proper functioning of the injection.
• Consult a healthcare professional for personalized dietary advice and to discuss any specific food-related concerns.

Chorionic Gonadotrophin injection should be stored in a controlled environment, specifically between 2°C and 8°C (refrigerated) in the original packaging to maintain its integrity and potency. It is crucial to keep the injection away from direct sunlight, as light exposure can degrade the medication. Do not freeze the injection as it may affect its effectiveness. Once opened, the injection should be used immediately, and any unused portion should be discarded. Proper disposal is essential to prevent misuse and environmental contamination; do not dispose of in regular trash or pour down the drain. Contact your healthcare provider or pharmacist for guidance on safe disposal methods.

Following are the quick tips for Chorionic Gonadotrophin injection:

• Store the injection at the recommended temperature, usually between 2°C and 8°C (refrigerated).
• Check the expiration date before use and do not use if expired.
• Ensure the injection is clear and free from particles. Do not use if it appears discolored or cloudy.
• Follow the prescribed dosage and administration instructions provided by your healthcare professional.
• Dispose of used needles and syringes safely in a puncture-proof container.
• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Do not reuse or share the injection equipment to prevent infections and ensure proper hygiene.
• Consult your healthcare provider if you have any concerns or experience unusual symptoms after the injection.