Prevomit FT (10mg) 10 Tablets

Pyridoxine, also known as vitamin B6, exerts its therapeutic effects primarily through its role as a coenzyme in various enzymatic reactions in the body. It is involved in more than 100 enzymatic reactions, many of which are related to amino acid metabolism. Pyridoxine acts as a cofactor for enzymes such as transaminases, which are crucial for the synthesis and breakdown of amino acids. This involvement in amino acid metabolism is essential for numerous physiological processes, including the production of neurotransmitters like serotonin, dopamine, and gamma-aminobutyric acid (GABA), which are critical for maintaining normal brain function and mood regulation. Additionally, pyridoxine plays a role in the metabolism of homocysteine, helping to convert it to other amino acids and thereby supporting cardiovascular health. The mechanism of action of pyridoxine is centered around its ability to facilitate these enzymatic reactions, thereby supporting a wide range of metabolic processes and contributing to overall physiological balance.

Vitamin B6 derivative

Tablet

The following are the uses of Pyridoxine Tablet:

• Used for treating Vitamin B6 deficiency, ensuring the body gets the essential nutrient.
• Used for addressing certain blood disorders, helping in the production of healthy blood cells.
• Used to alleviate symptoms of morning sickness and nausea during pregnancy.
• Used for improving nerve function and treating nerve pain in specific medical conditions.
• Used for managing seizures and certain types of epilepsy in combination with other medications.
• Used for supporting the body's metabolism and energy production processes.
• Used to enhance the absorption of certain nutrients, particularly in individuals with digestive issues.
• Used as a supplement to boost overall health and immune function.

In the case of an overdose of Pyridoxine Tablets, it is important to recognize the symptoms, which may include sensory changes, difficulty walking, and numbness in the hands and feet. If an overdose is suspected, prompt medical advice should be sought. The patient should be monitored for any adverse effects, and appropriate supportive measures should be taken. Treatment may involve managing symptoms and providing necessary medical care to prevent further complications.

In the case of a missed dose of Pyridoxine Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects. It is important to maintain a consistent routine with your medication, but if you miss a dose occasionally, simply resume your regular schedule without doubling the dose.

To take Pyridoxine Tablets, swallow the tablet whole with a glass of water, following the dosage instructions provided by your healthcare professional, typically once or twice a day, without crushing or chewing the tablet.

Here are the situations when Pyridoxine Tablet should not be used:

• Avoid using if you have a known allergy or sensitivity to Pyridoxine or any B-vitamin complex.
• Do not take if you have a rare genetic disorder called hyperoxaluria, as it can increase the risk of kidney stones.
• Not recommended for individuals with a type of anemia called sideroblastic anemia.
• Contraindicated in patients with certain genetic disorders affecting the nervous system, such as homocystinuria.
• Should not be used to treat peripheral neuropathy unless diagnosed and prescribed by a healthcare professional.
• Avoid high doses during pregnancy and breastfeeding, as it may cause adverse effects in the baby.
• Do not use Pyridoxine to treat any condition without medical supervision, especially in cases of suspected vitamin B6 deficiency.

The side effects of Pyridoxine Tablet may include:

• Nausea and vomiting
• Abdominal pain or discomfort
• Loss of appetite
• Sensitivity to sunlight (photosensitivity)
• Skin reactions such as rash or itching
• Difficulty sleeping (insomnia)
• Numbness or tingling in hands and feet
• Confusion or disorientation

Following are the precautions and warnings for Pyridoxine Tablet:

• Pyridoxine Tablets should not be taken if you have a known allergy to vitamin B6 or any of the tablet's components.
• Individuals with kidney disease should exercise caution and consult a healthcare professional, as dosage adjustments may be necessary.
• This medication may cause drowsiness; caution is advised when performing tasks requiring alertness, such as driving or operating machinery.
• Alcohol consumption should be avoided or limited while taking Pyridoxine Tablets as it may increase the risk of side effects.
• Do not exceed the recommended dosage without medical supervision, as high doses of vitamin B6 can lead to nerve damage.
• Pregnant and breastfeeding women should consult their doctor before taking Pyridoxine Tablets to ensure safe usage.
• If you have any pre-existing medical conditions or are taking other medications, inform your healthcare provider to prevent potential drug interactions.

Following are the drug interactions for Pyridoxine Tablet:

• Pyridoxine may reduce the effectiveness of levodopa, a medication used in Parkinson's disease, when taken concurrently.
• It can decrease the effects of tetracycline and other antibiotics, potentially reducing their efficacy.
• Pyridoxine can interact with anti-tuberculosis medications like isoniazid, possibly increasing the risk of peripheral neuropathy.
• It may reduce the absorption of penicillamine, a drug used in rheumatoid arthritis, leading to decreased therapeutic effects.
• Concomitant use with chemotherapy drugs like 5-fluorouracil may decrease the efficacy of the cancer treatment.
• Pyridoxine can lower the effectiveness of phenytoin, an anti-seizure medication, potentially requiring dose adjustments.
• It may reduce the anti-diabetic effects of certain medications, such as chlorpropamide and tolbutamide.

Following are the food interactions for Pyridoxine Tablet:

• Pyridoxine may reduce the effectiveness of levodopa, a medication used in Parkinson's disease, so patients should maintain a consistent intake of protein and carbohydrates to minimize this interaction.
• Alcohol can interfere with the absorption of Pyridoxine, hence it is advisable to limit or avoid alcohol consumption during treatment.
• High-protein diets may increase the requirement for Pyridoxine, as the vitamin is involved in protein metabolism.
• Vitamin B6 (Pyridoxine) and magnesium can have a synergistic effect, so foods rich in magnesium like nuts, seeds, and whole grains can be beneficial.
• Vitamin B6 helps in the metabolism of tryptophan, an amino acid found in foods like turkey, eggs, and dairy. A balanced diet ensures optimal tryptophan levels.
• Some studies suggest that high doses of Pyridoxine may reduce the effectiveness of penicillamine, a medication used for rheumatoid arthritis.
• Caffeine may increase the excretion of Pyridoxine, so excessive caffeine intake should be avoided.
• Pyridoxine is involved in the metabolism of histamine, so a diet low in histamine-rich foods like fermented items and aged cheeses might be recommended in certain cases.

Pyridoxine Tablets should be stored in a cool and dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air and humidity. Do not store them in the bathroom or kitchen, as these areas can be prone to temperature fluctuations. Dispose of any unused or expired tablets by following local guidelines for pharmaceutical waste disposal, and do not flush them down the toilet or discard them into the environment. Always keep medications out of the sight and reach of children and pets to prevent accidental consumption.

Following are the quick tips for Pyridoxine Tablet:

• Consult your doctor or pharmacist before use if you have any medical conditions or allergies.
• Take the tablet as directed by your healthcare provider, typically with a full glass of water.
• Maintain a consistent daily routine for taking the medication.
• Avoid crushing or chewing the tablet; swallow it whole for optimal absorption.
• Do not double the dose to make up for a missed one; continue with the regular schedule.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Inform your doctor if you are pregnant, breastfeeding, or planning a pregnancy.