PRIORIX VACCINE(MMR)

The Rubella, Measles, and Mumps Vaccine is a combination vaccine that works by stimulating the body's immune system to produce antibodies against three different viruses, Rubella, Measles, and Mumps. The vaccine contains weakened or attenuated forms of these viruses, which are unable to cause a full-blown infection but are sufficient to trigger an immune response. When the vaccine is administered, the immune system recognizes the viral antigens and produces antibodies specific to each virus. For Rubella, the vaccine induces the production of antibodies against the rubella virus, providing immunity and preventing future infections. Similarly, the Measles component stimulates the creation of measles-specific antibodies, offering protection against measles disease. The Mumps portion of the vaccine prompts the immune system to generate antibodies targeting the mumps virus, thereby safeguarding against mumps infections. This immune response, elicited by the vaccine, helps the body recognize and combat these viruses if future exposure occurs, reducing the risk of developing rubella, measles, and mumps.

Live Attenuated Virus Vaccine

Injection

The following are the uses of Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection:

• Used for preventing rubella, a contagious viral infection that can cause severe complications in pregnant women and their unborn babies.
• Used to protect against measles, a highly contagious respiratory disease that can lead to severe health issues, especially in children.
• Effective in preventing mumps, a viral infection causing painful swelling of the salivary glands, which can lead to potential complications like meningitis.
• Used for immunization against measles, mumps, and rubella (MMR) in a single injection, offering protection against all three diseases.
• Helps control and eradicate these diseases by providing widespread immunity, reducing their transmission, and minimizing outbreaks.
• Used for post-exposure prophylaxis to prevent the onset of measles, mumps, or rubella in individuals who have been exposed to the viruses.
• Essential for maintaining herd immunity, ensuring that vulnerable individuals who cannot receive the vaccine are indirectly protected.
• Used in travel medicine to ensure individuals are protected when traveling to regions where these diseases may be prevalent.

In the case of an overdose of Rubella Vaccine, Measles Vaccine, and Mumps Vaccine Injection, it is important to note that these vaccines are generally safe and well-tolerated. However, if an overdose occurs, symptoms may include mild fever, rash, or soreness at the injection site. In rare cases, an overdose could lead to a more severe allergic reaction, but this is highly unlikely. The specific effects of an overdose would depend on the individual's health and the amount of vaccine administered. It is always recommended to consult a healthcare professional if there are concerns regarding vaccine administration.

In the case of a missed dose of the Rubella, Measles, and Mumps Vaccine, it is important to consult your healthcare provider as soon as possible. They will advise you on the appropriate action, which may include scheduling a new vaccination appointment. Typically, if a dose is missed, the vaccine can be administered at a later date, ensuring the full course is completed. It is crucial to follow the recommended schedule to maintain optimal protection against these diseases. Don't hesitate to seek guidance from your healthcare provider to ensure you stay on track with your vaccinations.

To administer the combined Rubella, Measles, and Mumps Vaccine Injection, ensure the vaccine is at room temperature. Clean the injection site with an alcohol wipe. Insert the needle at a 45-degree angle, inject the vaccine intramuscularly, and then withdraw the needle. Apply pressure with a sterile gauze pad if needed, and discard the used needle in a puncture-proof container. It is crucial to follow the recommended dosage and schedule provided by your healthcare provider for this vaccine.

Here are the conditions or situations when the combined Rubella, Measles, and Mumps Vaccine Injection should not be administered:

• Do not administer if the individual has a severe, life-threatening allergic reaction to a previous dose of this vaccine or any of its components.
• Avoid if the person has a known severe allergy to gelatin, neomycin, or any other component of the vaccine.
• Not suitable for individuals with a weakened immune system due to a medical condition or treatment (e.g., HIV/AIDS, cancer, radiation therapy).
• Should not be used in patients with a history of severe immunodeficiency or individuals receiving immunosuppressive therapy.
• Contraindicated in pregnant women, as the potential effects on fetal development are not fully established.
• Avoid if the person has a moderate or severe illness with a fever. The vaccine can be given after recovery.
• Not recommended for individuals with a history of thrombocytopenia (low platelet count) after receiving the vaccine in the past.
• Do not administer if there is a history of severe allergic reaction to eggs, as some of the vaccines may contain trace amounts of egg protein.
• Should not be used in individuals with a history of brain inflammation or encephalopathy within 6 weeks of a previous measles vaccine.
• Avoid if the person has a history of severe neurological disorders or family history of congenital or hereditary immunodeficiency.
• Not suitable for individuals with a history of seizures or a condition that can cause seizures, as the vaccine may increase the risk of febrile seizures.
• Should not be administered to individuals with a history of severe allergic reaction to any vaccine containing similar components.
• Contraindicated in individuals with a history of blood disorders or conditions affecting the bone marrow.
• Do not use if the person has a history of cancer or is currently undergoing cancer treatment.
• Avoid if the individual has a history of severe allergic reaction to latex,

The side effects of the Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection may include:

• Mild fever
• Rash
• Swollen lymph nodes
• Headache
• Joint pain and stiffness
• Temporary low platelet count
• Allergic reaction at the injection site (redness, swelling, and pain)
• Mild to moderate pain in joints, especially in teenagers and adults.

Following are the precautions and warnings for Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection:

• Do not administer to individuals with a history of severe allergic reactions to any component of the vaccine, including gelatin or neomycin.
• Not recommended for pregnant women. Pregnant women should avoid becoming pregnant for at least 3 months after vaccination.
• Exercise caution in individuals with a history of severe allergies or individuals with compromised immune systems.
• Mild illnesses are not a contraindication, but vaccination should be postponed in cases of moderate or severe acute illness.
• Inform the healthcare provider if the individual has a bleeding disorder or is currently on blood-thinning medications.
• Temporary immune system weakness after vaccination may lead to a higher risk of developing infections.
• As with any vaccine, there is a small risk of a severe allergic reaction (anaphylaxis). Ensure medical treatment is readily available.

Following are the drug interactions for Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection:

• Live attenuated viral vaccines, including MMR, should not be given to individuals receiving immunosuppressive therapy due to potential decreased vaccine effectiveness.
• Avoid concurrent use with blood products as they may interfere with vaccine response.
• Radiation therapy can reduce the effectiveness of live attenuated vaccines. Vaccination should be delayed until after completion of radiation treatment.
• The vaccine may interact with other live vaccines (e.g., varicella, BCG), potentially increasing the risk of adverse reactions. Separate administration by at least 4 weeks is recommended.
• Corticosteroids and other immunosuppressive drugs may reduce the immune response to the vaccine. Consider delaying vaccination until after immunosuppressive therapy.
• Antimetabolites like methotrexate and azathioprine may reduce the effectiveness of the vaccine. Consult a healthcare professional for appropriate timing of vaccination.
• Certain biological agents (e.g., anti-TNF medications) may affect vaccine response. Discuss with a specialist to determine the best timing for vaccination.

Following are the food interactions for Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection:

• Avoid consuming alcohol after vaccination, as it may reduce the effectiveness of the vaccine and can interfere with the immune response.
• Maintain a well-balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support your immune system and overall health.
• Stay hydrated by drinking plenty of fluids, especially water, to ensure optimal immune function.
• There is no specific food restriction, but it's advisable to avoid spicy or heavy meals immediately after vaccination to prevent any potential gastrointestinal discomfort.
• Avoid grapefruit and grapefruit juice as they may interact with some medications and vaccines, although there is no direct evidence with this vaccine.
• Ensure you follow any specific dietary guidelines provided by your healthcare provider, especially if you have any underlying health conditions.
• Certain foods rich in antioxidants and vitamins, like berries, citrus fruits, and leafy greens, can support immune function and aid in the recovery process.

Rubella, Measles, and Mumps Vaccine Injections should be stored and disposed of properly to maintain their effectiveness and ensure safety. Store the vaccines in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F), ensuring they are not frozen as this can damage the vaccine. Keep the vials in their original packaging to protect from light and moisture. Do not use the vaccine if it has been frozen or exposed to extreme temperatures. Dispose of any unused or expired vaccine according to local regulations and guidelines, and never throw it in the regular trash or pour it down the drain. Consult healthcare professionals or pharmacists for specific instructions on proper disposal methods to prevent any potential risks. Keep all medications, including vaccines, out of the reach of children to avoid accidental exposure.

Following are the quick tips for Rubella Vaccine, Measles Vaccine, Mumps Vaccine Injection:

• Administer the vaccine as per the recommended schedule to ensure effectiveness.
• Follow the healthcare provider's instructions for dosage and administration.
• Ensure the vaccine is stored at the appropriate temperature.
• Inform the healthcare provider about any allergies or medical conditions before vaccination.
• Report any severe reactions or side effects immediately to your healthcare provider.
• Avoid touching or reusing the injection site after vaccination.
• Maintain a record of your vaccination for future reference.