Prisa (10mg) 14 Tablets

Prasugrel is a prodrug that belongs to the thienopyridine class of antiplatelet medications. Its mechanism of action involves the irreversible inhibition of the P2Y12 receptors on platelets. When activated, Prasugrel is rapidly converted to its active metabolite, which selectively and irreversibly inhibits the P2Y12 receptors. This inhibition prevents the binding of ADP (adenosine diphosphate) to the P2Y12 receptors, leading to reduced platelet activation and aggregation. By blocking the P2Y12 receptors, Prasugrel inhibits platelet aggregation, thrombus formation, and the subsequent risk of arterial thrombosis, making it effective in preventing thrombotic events in certain cardiovascular conditions.

Thienopyridine antiplatelet agent

Tablet

The following are the uses of Prasugrel 10MG Tablet:

• Used for preventing blood clots in patients with acute coronary syndrome who undergo a procedure known as percutaneous coronary intervention (PCI).
• Used to reduce the risk of heart attacks, strokes, and cardiovascular death in high-risk individuals.
• Used for managing unstable angina and reducing recurrent chest pain.
• Used in patients with a history of heart attacks to prevent future cardiac events.
• Used to improve blood flow in blocked arteries and maintain open blood vessels after PCI.
• Used as an antiplatelet agent to inhibit platelet aggregation and clot formation.
• Used in combination with aspirin for enhanced therapeutic effects in certain patients.

In the case of an overdose of Prasugrel 10MG Tablet, it is important to recognize the signs and take appropriate action. Overdose symptoms may include prolonged bleeding, easy bruising, and fatigue. If an overdose is suspected, immediate medical attention should be sought. Contact a healthcare professional or emergency services for guidance on managing the overdose, as they can provide specific instructions based on the individual's condition. Quick response and medical intervention are vital in such situations.

In the case of a missed dose of Prasugrel 10MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of bleeding. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or adjust the dosage accordingly. It is essential to maintain a consistent medication routine for the best therapeutic effect.

To take Prasugrel 10MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, who will determine the appropriate dosage based on your medical condition and response to treatment.

Following are the conditions when Prasugrel 10MG Tablet should not be used:

• Must not be taken by individuals with a known allergy or hypersensitivity to Prasugrel or any of its inactive components.
• Contraindicated in patients with active bleeding or a history of bleeding disorders, such as thrombocytopenia.
• Should not be used in individuals with a history of stroke or transient ischemic attack (TIA).
• Not recommended for patients with severe liver disease or impaired liver function.
• Contraindicated in patients with a history of intracranial hemorrhage or bleeding inside the skull.
• Must be avoided by individuals with severe kidney disease or those on dialysis.
• Not suitable for patients with a history of gastrointestinal ulcers or bleeding.
• Should not be used in patients who have recently undergone major surgery, especially brain or spinal surgery.
• Contraindicated in pregnant or breastfeeding women due to potential risks to the fetus or infant.
• Should be used with caution and under medical supervision in elderly patients, as they may be more prone to bleeding risks.

The side effects of Prasugrel 10MG Tablet may include:

• Easy bruising or bleeding (nosebleeds, bleeding gums)
• Feeling tired or weak
• Headache
• Stomach pain or upset
• Nausea and vomiting
• Diarrhea
• Skin rash or itching

Following are the precautions and warnings for Prasugrel 10MG Tablet:

• Prasugrel should not be used in patients with active bleeding disorders or a history of stroke, as it can increase the risk of bleeding.
• Patients must inform their doctor about any previous allergies or reactions to Prasugrel or similar medications.
• This medication may increase the risk of bleeding during surgery or invasive procedures, so inform your doctor if you are scheduled for any such procedures.
• Patients with liver or kidney disease should use Prasugrel with caution, as dosage adjustments may be necessary.
• It is important to avoid activities that can increase the risk of bleeding, such as contact sports or activities with a high risk of injury.
• Patients should not stop taking Prasugrel without consulting their doctor, as sudden discontinuation may increase the risk of cardiovascular events.
• Pregnant or breastfeeding women should consult their doctor before using Prasugrel, as it may have potential risks to the fetus or infant.
• Prasugrel may interact with other medications, including antiplatelet drugs and anticoagulants, so inform your doctor about all medications you are currently taking.

Following are the drug interactions for Prasugrel 10MG Tablet:

• Concomitant use with other antiplatelet agents (e.g., clopidogrel, ticagrelor) may increase the risk of bleeding due to additive effects on platelet inhibition.
• Prasugrel should not be used with oral anticoagulants like warfarin, as it significantly increases the risk of major bleeding events.
• Thrombolytic agents, such as alteplase, when used with Prasugrel, can elevate bleeding risks, particularly in acute coronary syndrome patients.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) may further enhance the antiplatelet effect of Prasugrel, increasing the potential for bleeding complications.
• Proton pump inhibitors (PPIs) like omeprazole can reduce the effectiveness of Prasugrel, potentially leading to inadequate platelet inhibition.
• Caution is advised when using Prasugrel with CYP3A4 and CYP2B6 inhibitors, as these may increase Prasugrel exposure, possibly leading to increased bleeding risks.
• The effectiveness of Prasugrel may be reduced when used with CYP2B6 and CYP3A4 inducers, potentially compromising its antiplatelet effect.

Following are the food interactions to be aware of when taking Prasugrel 10MG Tablet:

• Avoid grapefruit and grapefruit juice as they can affect the metabolism of Prasugrel, potentially leading to increased blood levels and an elevated risk of bleeding.
• Alcohol consumption should be limited as it can increase the risk of bleeding and may interfere with the antiplatelet effect of Prasugrel.
• Fatty meals may slightly decrease the absorption of Prasugrel, but this effect is not considered clinically significant.
• Avoid cranberry juice as it can potentially decrease the effectiveness of Prasugrel by affecting platelet function.
• Vitamin K-rich foods like leafy green vegetables, broccoli, and liver should be consumed in moderation as they can counteract the anticoagulant effect of Prasugrel.
• Garlic supplements may increase the risk of bleeding when taken with Prasugrel due to their antiplatelet properties.
• Avoid excessive use of spices like ginger and turmeric, as they may have blood-thinning properties and potentially increase the risk of bleeding.
• Always inform your healthcare provider about your diet and any herbal supplements you take to ensure safe and effective use of Prasugrel.

Prasugrel 10MG Tablets should be stored in a cool and dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Keep the medication in its original container, tightly sealed, to ensure its integrity and protect it from moisture and light. It is crucial not to store Prasugrel in the bathroom or near sinks as exposure to moisture can impact its effectiveness. Additionally, keep it away from direct heat sources like radiators or ovens. Always check the expiration date, and if the tablets have expired or are no longer needed, do not flush them down the toilet or throw them into the trash. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods to protect the environment. Keep this medication securely locked away from children and pets to prevent accidental consumption.

Following are the quick tips for Prasugrel 10MG Tablet:

• Consult your doctor for the right dosage and duration based on your medical condition.
• Take this medicine as directed, usually once daily with or without food.
• Do not crush, chew, or break the tablet; swallow it whole.
• If you have difficulty swallowing, consider taking it with water or ask your pharmacist for advice.
• Avoid skipping doses; maintain a consistent schedule for better effectiveness.
• Inform your doctor about all medications you are taking to prevent potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.