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Propylthiouracil (PTU) is an antithyroid medication that primarily acts by inhibiting the enzyme thyroid peroxidase (TPO). This enzyme is crucial for the synthesis of thyroid hormones, thyroxine (T4) and triiodothyronine (T3). By blocking TPO, PTU decreases the production of these hormones. It also exhibits an additional mechanism by competitively inhibiting the iodination of thyroglobulin, further reducing thyroid hormone synthesis. Moreover, PTU may interfere with the peripheral conversion of T4 to the more active form, T3, in tissues outside the thyroid gland. This comprehensive inhibition of thyroid hormone production and conversion makes PTU effective in controlling hyperthyroidism.
Antithyroid
Tablet
The following are the uses of Propylthiouracil Tablet:
In the case of an overdose of Propylthiouracil Tablets, it is important to recognize the potential severity of the situation. Symptoms may include nausea, vomiting, diarrhea, and abdominal pain. More serious effects can include liver damage, kidney problems, and severe blood disorders. Prompt medical attention is necessary, as doctors may need to provide supportive care and manage any life-threatening complications that arise from the overdose. Seeking emergency assistance is crucial for the best possible outcome.
In the case of a missed dose of Propylthiouracil Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your medication regimen. It is essential to maintain a consistent medication routine, but if you encounter challenges, consult your healthcare provider for advice.
To take Propylthiouracil Tablets, swallow the tablet whole with a full glass of water, usually two to four times a day or as directed by your doctor, and it is important to follow the prescribed dosage and schedule provided by your healthcare professional.
Following are the conditions/situations when Propylthiouracil Tablet should not be used:
The side effects of Propylthiouracil Tablet may include:
Following are the precautions and warnings for Propylthiouracil Tablet:
Following are the drug interactions for Propylthiouracil Tablet:
Following are the food interactions for Propylthiouracil Tablet:
Propylthiouracil Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storage in bathrooms or near heat-emitting appliances. Regularly check the expiration date, and if the tablets are no longer needed or have expired, proper disposal is essential. Do not dispose of them in household waste or down the drain; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication securely locked away from children to prevent accidental consumption.
Following are the quick tips for Propylthiouracil Tablet:
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