Proglobe (400mg) 10 Tablets

Bacampicillin HCl 400mg Tablet acts by inhibiting the synthesis of the bacterial cell wall. It is a prodrug that is rapidly converted to ampicillin in the body, which is a broad-spectrum antibiotic belonging to the penicillin group. Ampicillin primarily interferes with the synthesis of peptidoglycan, a crucial component of the bacterial cell wall, by binding to and inhibiting the action of enzymes called transpeptidases. This disruption in cell wall formation leads to weakened cell structure and ultimately results in the death of susceptible bacteria. Specifically, bacampicillin, through its active form ampicillin, targets the final stages of cell wall synthesis, preventing the cross-linking of peptidoglycan chains, which is essential for maintaining the structural integrity of the bacterial cell.

Bacampicillin Hcl 400mg

Penicillin derivative.

Tablet

The following are the uses of Bacampicillin Hcl 400mg Tablet:

• Used for treating respiratory tract infections like pneumonia, bronchitis, and sinusitis.
• Used for managing ear, nose, and throat infections, including tonsillitis and otitis media.
• Used for curing urinary tract infections, such as cystitis and urethritis.
• Used for addressing skin and soft tissue infections, including cellulitis and abscesses.
• Used for controlling gynecological infections, especially in the treatment of pelvic inflammatory disease.
• Used for managing dental infections, including abscesses and post-operative infections.
• Used for severe infections that require high oral doses of penicillin.

In the case of an overdose of Bacampicillin Hcl 400mg Tablets, individuals may experience an array of symptoms. These can include nausea, vomiting, diarrhea, and abdominal pain. Overdose may also lead to more severe complications, such as an increased risk of infections and potential damage to the kidneys. It is important to seek medical advice promptly if an overdose is suspected, as early intervention can help manage these symptoms effectively and prevent further health issues.

In the case of a missed dose of Bacampicillin Hcl 400mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is advisable to maintain a consistent dosing routine to ensure the medication's effectiveness.

To take Bacampicillin Hcl 400mg Tablet, swallow the tablet whole with a full glass of water, ensuring you follow the prescription instructions provided by your healthcare professional regarding the dosage and frequency of administration.

Following are the conditions when Bacampicillin Hcl 400mg Tablet should not be used:

• Do not take if you are allergic to any penicillin antibiotics or have a history of severe allergic reactions to similar medications.
• Avoid using this medication if you have a history of severe gastrointestinal problems, such as colitis or severe diarrhea caused by antibiotics.
• Not suitable for individuals with kidney disease or impairment as it may require dosage adjustments.
• Do not use if you have a history of severe liver disease or if you currently have liver problems.
• Contraindicated in individuals with a known sensitivity or reaction to any of the tablet's components.
• Should not be used to treat viral infections such as the common cold or flu.

Side effects of Bacampicillin Hcl 400mg Tablet:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Skin rash
• Itching
• Headache
• Dizziness
• Allergic reactions (swelling of the face, lips, tongue, or throat)
• Difficulty breathing
• Unusual tiredness or weakness
• Dark urine
• Yellowing of the skin or eyes

Following are the precautions and warnings for Bacampicillin HCl 400mg Tablet:

• Allergic reactions may occur; patients with a known allergy to penicillin or any other beta-lactam antibiotic should not take this medication.
• Kidney function should be monitored during long-term treatment, as Bacampicillin can cause kidney-related side effects.
• May cause diarrhea; if severe or persistent, consult a healthcare professional as it may indicate a more serious condition.
• Caution in patients with a history of gastrointestinal diseases, as Bacampicillin can exacerbate these conditions.
• Should not be used to treat viral infections, as it is ineffective against viruses.
• May reduce the effectiveness of birth control pills, so alternative contraceptive methods should be considered during treatment.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may pose risks to the fetus or infant.

Following are the drug interactions for Bacampicillin Hcl 400mg Tablet:

• Allopurinol may reduce the excretion of Bacampicillin, leading to increased blood levels and potential toxicity.
• Probenecid can decrease the renal tubular secretion of Bacampicillin, resulting in higher plasma concentrations.
• Concomitant use with Methotrexate may increase the risk of Methotrexate toxicity by decreasing its renal clearance.
• Bacampicillin can reduce the efficacy of oral contraceptives, requiring alternative birth control methods.
• Alcohol consumption may enhance gastrointestinal side effects and should be avoided.
• May reduce the absorption of iron supplements when taken simultaneously.
• The efficacy of Bacampicillin may be decreased when taken with antacids containing aluminum or magnesium.

Following are the food interactions for Bacampicillin Hcl 400mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can affect the metabolism of the drug, potentially leading to increased drug levels in the body.
• Alcohol intake is not recommended as it may reduce the absorption of Bacampicillin, decreasing its effectiveness.
• Dairy products like milk, yogurt, or cheese may interfere with the absorption of this medicine, so it is best to separate them by a few hours.
• High-fat meals can delay the absorption of Bacampicillin, potentially affecting its efficacy.
• Avoid caffeine-rich foods and beverages as they may increase the elimination of Bacampicillin, reducing its effectiveness.
• Vitamin C-rich foods like citrus fruits and broccoli may decrease the absorption of Bacampicillin, so it's advisable to separate them by a few hours.
• Probiotics and fermented foods may reduce the effectiveness of Bacampicillin due to their potential interactions with the medication.
• Consult your healthcare provider for specific dietary recommendations as they may provide personalized advice based on your medical history.

Bacampicillin Hcl 400mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the medication in its original container, tightly sealed, to maintain its integrity. Avoid exposure to heat or cold extremes as it may impact the drug's effectiveness. Always adhere to the expiration date on the packaging, and when disposing of unused or expired tablets, do not flush or pour them down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal guidelines to minimize environmental impact. Keep the medication securely stored, out of children's reach, to prevent accidental consumption.

Following are the quick tips for Bacampicillin Hcl 400mg Tablet:

• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Ensure you complete the full course of medication as prescribed.
• Take the tablet with a full glass of water to aid in swallowing.
• Avoid crushing or chewing the tablet; swallow it whole.
• Do not take with dairy products or antacids; they may interfere with absorption.
• Inform your doctor if you have any allergies or medical conditions before starting this medication.
• Contact your healthcare provider if you experience any severe side effects or allergic reactions.