PROTUSS 120ML SYP

Levodropropizine is a cough suppressant that acts peripherally, primarily in the upper respiratory tract. Its mechanism of action involves targeting peripheral cough receptors without affecting the central nervous system. It is believed to work by inhibiting the sensitivity of these receptors, thereby reducing the cough reflex. Levodropropizine does not have any significant anticholinergic, antihistamine, or local anesthetic properties, making it a selective and effective antitussive agent. The precise molecular interactions and pathways through which it modulates cough receptor activity are still being studied, but its peripheral site of action contributes to its effectiveness and safety profile.

Levodropropizine

Levodropropizine:

Suspension

The following are the uses of Levodropropizine Syrup/Suspension:

• Used for treating dry, unproductive coughs and reducing coughing fits.
• Used to suppress cough reflexes and provide relief from persistent coughing.
• Used for managing coughs associated with respiratory tract infections.
• Used to soothe irritated throats and calm cough-related discomfort.
• Used for patients with chronic bronchitis to control chronic cough symptoms.
• Used to reduce coughing during sleep, aiding in better rest and recovery.
• Used as an alternative for individuals intolerant to other cough suppressants.

In the case of an overdose of Levodropropizine Syrup/Suspension, individuals may experience increased severity of common side effects such as drowsiness, dizziness, and gastrointestinal discomfort. The severity of these symptoms can vary depending on the amount ingested. It is crucial to seek medical advice promptly and provide healthcare professionals with information regarding the quantity consumed. Timely intervention can help manage symptoms and ensure appropriate medical care.

In the case of a missed dose of Levodropropizine Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to get back on track with your medication regimen. It is crucial to maintain consistency in taking this medication as prescribed.

To take Levodropropizine Syrup/Suspension, shake the bottle well, then measure the prescribed dose using a measuring cup or oral syringe, and administer it orally, typically two to three times a day, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Levodropropizine Syrup/Suspension should not be used:

• Not recommended for individuals with a known allergy to Levodropropizine or related compounds.
• Avoid in patients with a history of severe allergic reactions or hypersensitivity to any of the syrup/suspension's components.
• Should not be administered to patients with a history of bronchospasm or obstructive lung disease.
• Contraindicated in patients with liver impairment or active liver disease.
• Not suitable for children under 2 years of age due to potential safety concerns.
• Avoid using in patients with a history of gastrointestinal obstruction or severe gastrointestinal disorders.
• Not recommended for individuals with a history of seizures or epilepsy.
• Should not be used in patients with a history of kidney disease or significantly impaired renal function.

The side effects of Levodropropizine Syrup/Suspension may include:

• Nausea and vomiting
• Dizziness
• Headache
• Skin rash or itching
• Diarrhea
• Stomach pain
• Fatigue and drowsiness

Following are the precautions and warnings for Levodropropizine Syrup/Suspension:

• This medication is intended for oral use only. Do not inject or infuse.
• Not recommended for patients with a history of hypersensitivity or allergic reactions to Levodropropizine or any of the excipients in the syrup.
• Patients with severe liver or kidney impairment should exercise caution and consult a healthcare professional before use, as dosage adjustments may be necessary.
• Levodropropizine may cause drowsiness or dizziness in some individuals. Avoid driving, operating heavy machinery, or engaging in activities that require mental alertness until you know how this medication affects you.
• If symptoms persist, worsen, or new symptoms appear, discontinue use and seek medical advice immediately.
• The safety and efficacy of Levodropropizine Syrup/Suspension in children have not been established, and it should not be administered to children without medical supervision.
• Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding, as the potential risks and benefits should be carefully considered.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Levodropropizine Syrup/Suspension:

• Levodropropizine can interact with opioids, leading to increased risk of respiratory depression and sedation. Close monitoring is required.
• It may reduce the effectiveness of cough suppressants, as it stimulates the cough reflex.
• Antihistamines might enhance the sedative effects of Levodropropizine, causing excessive drowsiness.
• The syrup's effectiveness may be reduced when taken with antacids, as it can alter the stomach pH.
• Levodropropizine can increase the risk of arrhythmias when used with certain antiarrhythmic medications.
• It can potentially interact with other medications that affect the central nervous system, such as benzodiazepines and antipsychotics.
• Caution is advised when taking Levodropropizine with herbal remedies like Echinacea, as it may stimulate the immune system and potentially affect respiratory conditions.

Following are the food interactions for Levodropropizine Syrup/Suspension:

• Levodropropizine may cause drowsiness, so it is advised to avoid alcohol consumption as it can enhance this effect and impair your ability to drive or operate machinery.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Levodropropizine, potentially altering its effectiveness.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks should be limited as they may increase the excitability of the respiratory center, counteracting the cough-suppressing effect of Levodropropizine.
• Dairy products, especially milk, might interfere with the absorption of Levodropropizine. It is recommended to take the medication at least one hour before or two hours after consuming milk to ensure optimal absorption.
• High-fat meals can delay the absorption of Levodropropizine, possibly reducing its effectiveness. It is advisable to take the medication on an empty stomach or at least one hour before a meal.
• Avoid spicy foods as they can irritate the throat and exacerbate coughing, potentially reducing the efficacy of Levodropropizine.
• Certain citrus fruits like oranges and lemons may increase the production of mucus, which could potentially interfere with the action of Levodropropizine.
• Always ensure you are well-hydrated when taking Levodropropizine, as adequate fluid intake supports the medication's effectiveness and helps thin mucus, making it easier to clear.

Levodropropizine Syrup/Suspension storage and disposal should be done with caution to maintain its integrity and prevent misuse. Store the medication in a cool, dry area, preferably at room temperature, ensuring it remains untouched by direct sunlight or moisture. Keep the syrup securely sealed in its original packaging to maintain its purity. Avoid bathroom storage or placing it near heat sources like radiators or ovens, as temperature fluctuations can compromise the medicine's effectiveness. Regularly check the expiration date, and if the syrup is no longer needed or has expired, dispose of it responsibly. Do not dispose of it via toilet flushing or drainage; instead, seek advice from a pharmacist or healthcare professional for appropriate disposal methods. Lastly, ensure the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Levodropropizine Syrup/Suspension:

• Always follow your doctor's prescription for the correct dosage and duration.
• Before each use, shake the bottle to ensure proper mixing.
• Use a measuring cup or oral syringe for accurate dosing.
• Administer the syrup orally, and swallow it without chewing.
• Avoid mixing the syrup with other medications without medical advice.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Regularly monitor your symptoms and inform your doctor if they persist or worsen.