Pulsate (150mg) 10 Tablets

Roxithromycin 150mg Tablet primarily exhibits its antibacterial activity through its ability to inhibit protein synthesis in susceptible bacteria. It achieves this by binding to the 50S subunit of the bacterial ribosome, thereby preventing the elongation of peptide chains during translation. This binding interferes with the ribosome's ability to accurately read the mRNA sequence, leading to the production of faulty proteins and ultimately inhibiting bacterial growth and replication. Roxithromycin is particularly effective against a wide range of gram-positive and some gram-negative bacteria, making it a valuable antibiotic for treating various infections.

Macrolide antibiotic

Tablet

The following are the uses of Roxithromycin 150mg Tablet:

• Used for treating bacterial infections such as respiratory tract infections, skin infections, and soft tissue infections.
• Used for effective relief from acute flare-ups of chronic bronchitis.
• Used to combat certain types of pneumonia.
• Used for managing acute sinusitis.
• Used for treating certain ear infections like acute otitis media.
• Used for controlling infections in patients with reduced immune function.
• Used as an alternative for individuals allergic to penicillin-based antibiotics.

In the case of an overdose of Roxithromycin 150mg Tablets, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. Additionally, severe cases can lead to temporary hearing loss, headache, and dizziness. It is important to seek medical advice promptly if an overdose is suspected, as treatment may involve managing these symptoms and providing supportive care. Timely intervention can help mitigate potential health risks associated with Roxithromycin overdose.

In the case of a missed dose of Roxithromycin 150mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions based on your specific medical condition and treatment plan.

To take Roxithromycin 150mg Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, as directed by your healthcare professional, usually once or twice a day, at evenly spaced intervals.

Roxithromycin 150mg Tablet should not be used in the following conditions:

• Hypersensitivity or allergy to roxithromycin or other macrolide antibiotics.
• Severe liver impairment (hepatic failure).
• History of jaundice or hepatic dysfunction due to previous antibiotic use.
• Co-administration with certain medications, such as astemizole, terfenadine, or cisapride (due to risk of serious arrhythmias).
• In patients with known or suspected QT prolongation or arrhythmia.
• Children under 12 years (depending on the formulation and indication).
• Pregnancy (unless clearly required and prescribed by a doctor).
• Breastfeeding (unless specifically recommended by a healthcare professional).

The side effects of Roxithromycin 150mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Skin rashes or itching
• Dizziness
• Headache
• Altered sense of taste
• Elevated liver enzymes

Following are the precautions and warnings for Roxithromycin 150mg Tablet:

• Do not take this medication if you are allergic to Roxithromycin or similar antibiotics like Erythromycin.
• Inform your doctor if you have a history of liver or kidney disease, as it may affect the dosage and monitoring.
• This medication may cause dizziness or blurred vision, so avoid activities requiring mental alertness until you know how it affects you.
• Caution is advised for elderly patients as they may be more susceptible to side effects.
• Roxithromycin may interact with other medications; inform your doctor about all the medicines you are currently taking.
• Pregnant and breastfeeding women should consult their doctor before using this medication, as it may pose risks to the fetus or infant.
• Discontinue use and seek medical attention if you experience severe gastrointestinal symptoms or allergic reactions.

Following are the drug interactions for Roxithromycin 150mg Tablet:

• Erythromycin and other macrolide antibiotics may compete for the same metabolic pathways, leading to increased levels of either drug.
• Anticoagulants like Warfarin may have enhanced effects, requiring close monitoring of coagulation parameters.
• Theophylline levels can be increased, potentially leading to toxicity.
• Concomitant use with digoxin may increase digoxin levels, requiring dosage adjustments.
• Roxithromycin may elevate carbamazepine levels, necessitating monitoring for toxicity.
• It can reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• H2-receptor antagonists and proton pump inhibitors may decrease the absorption of Roxithromycin.

Following are the food interactions for Roxithromycin 150mg Tablet:

• Avoid grapefruit and grapefruit juice as they can increase the drug's concentration in the body, potentially leading to an increased risk of side effects.
• Alcohol consumption should be minimized or avoided as it may enhance the risk of liver-related side effects.
• Avoid high-fat meals as they may reduce the absorption of Roxithromycin, affecting its effectiveness.
• Dairy products like milk, cheese, and yogurt may decrease the absorption of the medicine, so consider separating them by a few hours.
• Avoid caffeine-rich foods and beverages as they may interact with Roxithromycin, causing increased side effects such as nervousness and rapid heartbeat.
• Consuming antioxidant-rich foods like berries, nuts, and dark chocolate may enhance the drug's effectiveness by supporting overall health.
• Stay well-hydrated by drinking plenty of water to aid in the absorption and distribution of the medication throughout the body.
• Consider taking the medication with a light meal or snack to minimize gastrointestinal side effects like nausea.

Roxithromycin 150mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent exposure to contaminants. Avoid storing near heat sources like radiators or stoves, as high temperatures can degrade the medication. Always check the expiration date, and if the tablets are no longer needed or have expired, do not flush them or throw them into the garbage. Consult your pharmacist or healthcare professional for guidance on proper disposal methods to minimize environmental impact. It is crucial to keep all medications, including Roxithromycin, out of children's reach to prevent accidental consumption.

Following are the quick tips for Roxithromycin 150mg Tablet:

• Take the tablet as directed by your doctor, typically once or twice a day.
• Swallow the tablet whole with a full glass of water, preferably before a meal.
• Complete the full course of medication, even if you feel better early on.
• Avoid consuming grapefruit or grapefruit juice while taking this medication.
• Inform your doctor if you have any liver or kidney issues before starting this medication.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share this medication with others, even if their symptoms appear similar.