Qumic (0.5%) 5ml Eye Drops

Qumic (0.5%) 5ml Eye Drops

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  • Manufacturer Bosch Pharmaceuticals (Pvt.) Ltd.
  • Generic Name

    Levofloxacin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Levofloxacin eye drops primarily act by inhibiting bacterial DNA gyrase, a type II topoisomerase enzyme essential for bacterial DNA replication, transcription, and repair. This inhibition occurs through the binding of levofloxacin to the A subunit of DNA gyrase, which interferes with the enzyme's ability to introduce negative supercoils into bacterial DNA, leading to DNA replication arrest and bacterial cell death. The drug's mechanism is highly specific for bacterial DNA gyrase, making it effective against a wide range of gram-positive and gram-negative bacteria. This targeted action contributes to its role in treating various bacterial eye infections.

  • Ingredients

    Levofloxacin

  • Drug Class

    Fluoroquinolone antibiotic.

  • Dosage Form

    Drop

  • Uses

    The following are the uses of Levofloxacin Drop:

    • Used for treating bacterial conjunctivitis, an infection of the eye
    • Used for reducing inflammation and clearing bacterial infections in the eye
    • Used for eye infections caused by specific bacteria that are sensitive to levofloxacin
    • Used for preventing the spread of bacterial eye infections, especially after eye injuries
    • Used for improving eye redness, itching, and discharge associated with bacterial conjunctivitis
    • Used for ensuring the infection is treated effectively to prevent potential vision issues
    • Used for providing relief from eye discomfort and promoting faster healing
    • Used for maintaining eye health and preventing complications from bacterial infections
  • In case of Overdose

    In the case of an overdose of Levofloxacin Drops, the severity of symptoms can vary. Common signs may include nausea, vomiting, and dizziness. More serious effects could lead to seizures, kidney problems, or an irregular heartbeat. It is crucial to seek medical assistance promptly, as healthcare professionals can provide specific guidance and treatment to manage the overdose effectively. Time is of the essence in such situations.

  • Missed Dose

    In the case of a missed dose of Levofloxacin eye drops, it is important to administer the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra drops or increase the frequency to make up for the missed dose. It is crucial to maintain a consistent application routine for the eye drops to ensure their effectiveness. If you frequently miss doses, it is best to consult your healthcare provider for guidance on how to manage your medication schedule.

  • How To Use

    To use Levofloxacin eye drops, wash your hands, tilt your head back, gently pull down the lower eyelid, hold the dropper above the eye, squeeze out a drop, close your eye gently, and apply pressure to the inner corner of the eye for 1-2 minutes to minimize drainage.

  • When Not to Use

    Following are the conditions when Levofloxacin Eye Drops should not be used:

    • Avoid using if you have a known allergy or hypersensitivity to Levofloxacin or other quinolone antibiotics.
    • Do not use if you have a history of tendon disorders or tendon rupture after taking Levofloxacin or similar medications.
    • Not recommended for individuals with myasthenia gravis, as it can worsen muscle weakness.
    • Contraindicated in patients with epilepsy or a history of seizures, as it may lower the seizure threshold.
    • Should not be used in children or adolescents, as it can affect bone and joint development.
    • Avoid using if you have a history of retinal detachment or other serious eye conditions.
    • Not suitable for individuals with corneal ulcers or infections caused by fungi or viruses.
    • Do not use if you have a history of sensitivity to any of the drop's components.
    • Avoid using if you are currently taking other medications that may interact adversely with Levofloxacin.
  • Side Effects

    The side effects of Levofloxacin Eye Drops may include:

    • Eye irritation or redness
    • Stinging or burning sensation in the eye
    • Watery eyes
    • Blurred vision
    • Sensitivity to light (photophobia)
    • Eye itching or discomfort
    • Swelling or discharge around the eye
    • Headache
  • Precautions & Warnings

    Following are the precautions and warnings for Levofloxacin Eye Drops:

    • Do not use Levofloxacin drops if you are allergic to any of its ingredients, including levofloxacin or other quinolone antibiotics.
    • If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes after administration before reinserting them to avoid contamination.
    • Do not touch the dropper tip to any surface, including your eye or hands, to prevent contamination.
    • Caution is advised in patients with a history of epilepsy or other seizure disorders, as Levofloxacin may lower the seizure threshold.
    • This medication is for ophthalmic use only; do not swallow or inject the drops.
    • If you are using other eye medications, apply them at least 5 minutes before or after Levofloxacin drops to prevent drug interactions.
    • Discontinue use and consult a doctor if you experience severe eye pain, worsening of symptoms, or signs of an allergic reaction.
    • Keep out of reach of children and pets.
  • Drug Interactions

    Following are the drug interactions for Levofloxacin Drops:

    • Theophylline levels can be increased, leading to potential toxicity.
    • May reduce the effectiveness of live attenuated vaccines (e.g., typhoid vaccine).
    • Concurrent use with non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system (CNS) stimulation and seizures.
    • Antacids containing aluminum, magnesium, or calcium can decrease the absorption of Levofloxacin.
    • Probenecid may increase the concentration of Levofloxacin by reducing renal excretion.
    • Warfarin interaction can lead to increased anticoagulant effects and bleeding risk.
    • The effectiveness of Tuberculosis drugs like Isoniazid and Rifampin may be reduced.
    • Levofloxacin may enhance the effects of anti-diabetic medications, causing hypoglycemia.
  • Food Interactions

    Following are the food interactions for Levofloxacin Drops:

    • Avoid consuming dairy products like milk, yogurt, or cheese, as they can decrease the absorption of Levofloxacin, reducing its effectiveness.
    • Grapefruit and grapefruit juice should be consumed cautiously as they can increase the levels of Levofloxacin in the blood, leading to potential side effects.
    • Alcohol intake should be minimized or avoided as it may increase the risk of central nervous system side effects, such as dizziness, lightheadedness, or confusion.
    • Avoid caffeine-rich foods and beverages like coffee, tea, or energy drinks, as they may enhance the stimulant effects of Levofloxacin, causing increased nervousness or insomnia.
    • Foods high in sugar and fat may not directly interact with Levofloxacin, but maintaining a healthy diet is essential to support overall health during the course of treatment.
    • Ensure adequate hydration by drinking plenty of water, as Levofloxacin can sometimes cause dehydration and increased urination.
    • If you have any specific dietary restrictions or concerns, consult your healthcare provider for personalized advice regarding food interactions with Levofloxacin drops.
  • Storage/Disposal

    Levofloxacin Eye Drops should be stored at room temperature, ideally between 68°F and 77°F (20°C and 25°C), in its original packaging or a tightly sealed container to maintain its integrity. It is crucial to keep the drops away from heat, direct light, and moisture, as these factors can degrade the medication. Always check the expiration date, and never use the drops if they have expired. For disposal, do not pour the medication down the sink or toilet; instead, contact your pharmacist or healthcare provider for guidance on safe disposal methods. Ensure that the medication is kept out of the reach of children and pets to prevent accidental exposure or ingestion.

  • Quick Tips, if any

    Following are the quick tips for Levofloxacin Drops:

    • Wash your hands thoroughly before administering the drops to maintain hygiene.
    • Tilt your head back and gently pull down the lower eyelid to create a pocket.
    • Hold the dropper close to the eye without touching it, and squeeze the prescribed number of drops into the pocket.
    • Close your eye gently and tilt your head down for a few minutes to prevent the drops from draining out.
    • Avoid touching the dropper tip to your eye or any surface to prevent contamination.
    • If using other eye medications, wait at least 5 minutes before applying the next medication.
    • Store the drops at room temperature, away from direct sunlight and moisture.

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