Rabicol (20mg) 10 Tablets

Rabeprazole 20mg tablets primarily work by inhibiting the gastric proton pump, which is responsible for acid secretion in the stomach. It achieves this by binding to and blocking the hydrogen-potassium adenosine triphosphatase enzyme system (also known as H+/K+ ATPase or the gastric proton pump) within the parietal cells of the stomach. This inhibition leads to a significant reduction in gastric acid secretion, resulting in less acidity in the stomach. By suppressing the production of gastric acid, Rabeprazole provides relief from various acid-related conditions and promotes the healing of gastrointestinal lesions.

Proton pump inhibitor

Tablet

The following are the uses of Rabeprazole 20mg Tablet:

• Used for treating acid reflux and heartburn, providing quick relief.
• Used to manage Gastroesophageal Reflux Disease (GERD) by reducing stomach acid.
• Effective in healing stomach ulcers and preventing their recurrence.
• Can be used to treat peptic ulcers, offering a targeted approach.
• Provides relief for acid-related conditions like Zollinger-Ellison Syndrome.
• Helps eradicate Helicobacter pylori (H. pylori) infections in the stomach.
• Used as a maintenance therapy to prevent acid-related damage.
• Can be combined with antibiotics for comprehensive treatment.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Gastroesophageal reflux disease (GERD) or heartburn - 20 mg once daily in the morning for up to 4 weeks, switch to prescription strength PPIs (like omeprazole) for continued use beyond 4 weeks.
• Ulcerative colitis - 20 mg once daily for 6 weeks.
• Duodenal ulcer - 20 mg once daily for 4 weeks.
• Stomach ulcer - 20 mg once daily for 4 weeks.
• Gastric cancer - 20 mg every morning preferably an hour before breakfast.
• Zollinger-Ellison syndrome - Initially, 20 mg once daily. The dose may be increased to 20 mg every day divided into two doses.

In the case of an overdose of Rabeprazole 20mg Tablets, it is important to recognize the potential symptoms and seek medical advice promptly. Overdose symptoms may include nausea, vomiting, abdominal pain, and dizziness. If you suspect an overdose, contact a healthcare professional or poison control center immediately for guidance. They will provide specific instructions based on the amount ingested and the patient's medical history, ensuring appropriate treatment and minimizing any potential risks associated with the overdose.

In the case of a missed dose of Rabeprazole 20mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss several doses, consult your healthcare provider for guidance on how to resume your treatment plan and ensure optimal management of your condition. It is generally recommended to take the missed dose within a few hours of the intended time to maintain the medication's effectiveness.

To take Rabeprazole 20mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning on an empty stomach, or as directed by your healthcare professional, without crushing or chewing it.

Here are the conditions and situations when Rabeprazole 20mg Tablet should not be taken:

• Avoid using if you are allergic to Rabeprazole or any other proton pump inhibitors (PPIs).
• Do not take this medication if you have severe liver problems, as it is metabolized by the liver.
• Contraindicated in patients with low magnesium levels (hypomagnesemia) or conditions causing low magnesium levels.
• Not recommended for long-term use; prolonged use may increase the risk of certain gastrointestinal issues and vitamin deficiencies.
• Should not be used if you have an inherited condition causing poor metabolism of certain medications.
• Avoid using if you have a history of osteoporosis or are at high risk, as long-term use may increase the risk of bone fractures.

The side effects of Rabeprazole 20mg Tablet may include:

• Headache
• Diarrhea
• Abdominal pain
• Nausea
• Dizziness
• Skin rash
• Increased risk of fractures (with long-term use)
• Vitamin B12 deficiency

Following are the precautions and warnings for Rabeprazole 20mg Tablet:

• Not recommended for long-term use; prolonged usage may increase the risk of bone fractures.
• Patients with liver problems should exercise caution, and regular liver function tests are advised during treatment.
• Elderly patients may be more susceptible to adverse effects, and dosage adjustments might be necessary.
• May cause vitamin B12 deficiency with long-term use, especially in patients with specific risk factors.
• Patients with a history of low magnesium levels or those taking diuretics should be monitored for hypomagnesemia.
• Not recommended for use in children unless advised by a healthcare professional.
• Consult a doctor if you have any underlying medical conditions or are taking other medications to ensure safe usage.

Following are the drug interactions for Rabeprazole 20mg Tablet:

• Concomitant use with Clopidogrel may reduce the effectiveness of Clopidogrel.
• It can decrease the absorption of Ketoconazole and increase the absorption of Digoxin.
• May reduce the absorption of drugs dependent on gastric pH for their dissolution, like Azole antifungals and iron salts.
• Rabeprazole can interact with Methotrexate, increasing its blood levels and potential toxicity.
• The effect of anticoagulants like Warfarin may be altered, requiring monitoring of INR.
• May reduce the absorption of certain antibiotics like Erythromycin and Ampicillin.
• Concomitant use with Atazanavir or other drugs highly dependent on gastric pH for absorption should be avoided.

Following are the food interactions for Rabeprazole 20mg Tablet:

• Avoid excessive consumption of acidic foods like citrus fruits, tomatoes, and spicy dishes, as they can irritate the stomach and potentially reduce the effectiveness of Rabeprazole.
• Caffeine-rich beverages such as coffee, tea, and energy drinks should be limited as they may stimulate acid production and worsen reflux symptoms.
• Alcohol can increase acid secretion and relax the lower esophageal sphincter, leading to acid reflux; it's advisable to minimize or avoid alcohol consumption.
• Avoid high-fat meals as they can delay stomach emptying and potentially prolong the presence of acid, which Rabeprazole aims to reduce.
• Consuming a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support overall digestive health and aid in managing conditions like gastroesophageal reflux disease (GERD).
• Stay well-hydrated by drinking adequate water throughout the day to promote healthy digestion and maintain the protective mucous lining in the stomach.
• Avoid carbonated drinks as they can cause gas and bloating, potentially exacerbating symptoms for some individuals.
• Grapefruit and grapefruit juice should be consumed with caution as they may interact with Rabeprazole, affecting its metabolism and potentially leading to increased side effects.

Rabeprazole 20mg Tablets should be stored in a cool and dry place, preferably at room temperature (below 25°C). Protect the tablets from light and moisture by keeping them in their original packaging or container. It is crucial not to expose the medication to heat or direct sunlight as it may affect its potency. Always check the expiration date before using the medication, and discard any expired tablets. When disposing of unused or expired Rabeprazole, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines or consult a pharmacist for safe disposal options to protect the environment. Keep the medication away from children and pets to prevent accidental consumption.

Following are the quick tips for Rabeprazole 20mg Tablet:

• Swallow the tablet whole, do not crush or chew it.
• Take the tablet on an empty stomach, preferably in the morning.
• Avoid missing doses; take it daily as prescribed for best results.
• If you forget a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Do not double the dose to make up for a missed one.
• Inform your doctor if you experience persistent headaches or diarrhea.
• Store the tablets in a cool, dry place, away from direct sunlight.

Rabeprazole is a proton pump inhibitor (PPI) that functions by reducing acid production in the stomach and is utilized to remedy stomach and duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. While Rabeprazole is generally safe, it may have potential side effects, and thus, lab tests are sometimes necessary to ensure its safe application. Among the laboratory tests that may be required are kidney function tests, which are essential as Rabeprazole can impact kidney function, especially in vulnerable populations such as older individuals or those with pre-existing kidney issues. Liver function tests may also be undertaken to check for liver inflammation or severe liver injury. Furthermore, there may be a need for blood chemistry and electrolyte tests to monitor for vitamin B12 deficiency and low magnesium levels in the blood, which can be a result of long-term PPI usage. For those taking Rabeprazole to treat an ulcer, more focused tests such as endoscopy may be recommended to assess healing and gauge the drug's efficacy. However, it is critical to emphasize that specific testing requirements should be clarified with a qualified healthcare provider, who can tailor recommendations based on one's unique conditions. Overall, while Rabeprazole is an effective treatment, lab tests may be necessary to ensure its safe and beneficial usage.