Rehydrole Powder 20 Sachet

The mechanism of action of Sodium Chloride and Sodium Citrate in a sachet formulation is primarily related to their respective roles in maintaining fluid and electrolyte balance in the body. Sodium Chloride (NaCl) is composed of sodium and chloride ions, which are essential electrolytes. When administered, it helps to replenish sodium and chloride levels in the body, especially in cases of electrolyte depletion or fluid loss. Sodium is crucial for maintaining extracellular fluid volume, supporting nerve impulse transmission, and aiding in muscle function. Chloride ions also contribute to acid-base balance and help regulate the body's pH. Sodium Citrate, on the other hand, acts as a citrate salt and provides citrate ions. Citrate ions play a role in buffering and maintaining the body's acid-base balance by binding to hydrogen ions, thereby helping to neutralize excess acidity in the blood. This buffering action is particularly important in preventing the formation of kidney stones and maintaining the stability of urine pH. The combination of Sodium Chloride and Sodium Citrate in a sachet formulation is often used to provide a balanced approach to electrolyte and fluid replacement, ensuring the body's hydration, electrolyte balance, and acid-base equilibrium are effectively maintained.

Antinauseant, Fluid replacement

powder

The following are the uses of Sodium chloride, sodium citrate Sachet:

• Used for seasoning and preserving food, adding flavor and extending shelf life.
• Used for rehydration therapy, treating dehydration by restoring electrolyte balance.
• Used for buffering and pH control in various laboratory and industrial processes.
• Used for enhancing food texture and improving the quality of processed meat products.
• Used for stabilizing and emulsifying functions in food and beverage production.
• Used for water softening in industrial and household applications.
• Used for enhancing dough strength and improving the texture of baked goods.
• Used for maintaining osmotic balance in medical treatments and research.

In the case of an overdose of Sodium Chloride and Sodium Citrate sachets, individuals may experience symptoms such as nausea, vomiting, diarrhea, and in severe cases, seizures or a loss of consciousness. If an overdose is suspected, it is crucial to seek medical advice promptly. Treatment involves managing the symptoms and providing supportive care to prevent further complications, especially for those with underlying health conditions. Prompt intervention can help mitigate the risks associated with excessive sodium intake.

In the case of a missed dose of Sodium Chloride and Sodium Citrate Sachet, it is generally recommended to take the missed dose as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for advice on how to safely resume your medication.

To use the Sodium Chloride and Sodium Citrate Sachet, pour the contents of the sachet into a glass of water, stir well until completely dissolved, and drink the entire mixture once daily or as directed by your healthcare provider.

Here are the conditions or situations when Sodium chloride, sodium citrate Sachet should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to sodium chloride, sodium citrate, or any of the excipients in the sachet.
• Contraindicated in patients with severe kidney disease or those on dialysis, as it can affect electrolyte balance.
• Should not be used in patients with high blood sodium levels (hypernatremia) or high blood citrate levels.
• Not recommended for individuals with a history of gastrointestinal obstruction or severe constipation.
• Avoid using in patients with uncontrolled high blood pressure (hypertension).
• Not suitable for patients with conditions that require a low-sodium diet, such as heart failure or liver cirrhosis.
• Contraindicated in individuals with a history of severe dehydration or those who are unable to maintain adequate fluid intake.
• Should not be used in patients with conditions that increase the risk of fluid overload, such as pulmonary edema or severe heart disease.

The side effects of Sodium Chloride and Sodium Citrate Sachet may include:

• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Constipation
• Excessive thirst
• Swelling in hands or feet
• High blood pressure
• Muscle weakness

Following are the precautions and warnings for Sodium Chloride, Sodium Citrate Sachet:

• Not recommended for individuals with heart issues, high blood pressure, or kidney problems.
• Those on a low-salt diet should exercise caution, as the sachet contains sodium.
• Avoid if you have a history of kidney stones or urinary tract infections.
• Always consult a healthcare professional before use, especially if you have any underlying medical conditions.
• Discontinue use and seek medical attention if you experience any adverse reactions such as nausea, vomiting, or increased thirst.
• Keep out of reach of children and pets.
• Do not exceed the recommended dosage, as excessive intake of sodium chloride and sodium citrate can lead to serious health complications.

Following are the drug interactions for Sodium Chloride, Sodium Citrate Sachet:

• May reduce the efficacy of lithium, leading to increased lithium levels and potential toxicity.
• Can increase the risk of hyperkalemia when used with ACE inhibitors or potassium-sparing diuretics.
• Antihypertensive effects of medications like beta-blockers and calcium channel blockers may be reduced.
• The diuretic effect of loop diuretics may be enhanced, potentially causing electrolyte imbalances.
• May decrease the absorption of various medications, including some antibiotics and antifungal drugs.
• Interaction with digoxin can lead to increased serum digoxin levels and potential toxicity.
• Could potentially reduce the effectiveness of medications for diabetes, requiring closer monitoring of blood glucose levels.

Following are the food interactions for Sodium Chloride, Sodium Citrate Sachet:

• Salt substitutes or reduced-sodium products may be recommended as high-sodium foods like processed meats, canned soups, and salty snacks should be limited in the diet to maintain a balanced sodium level.
• Foods rich in potassium such as bananas, oranges, tomatoes, and spinach can help restore electrolyte balance, especially if sodium levels are high.
• A diet rich in citrus fruits like lemons, limes, and oranges can aid in citrate supplementation, as they are natural sources of citric acid.
• Avoid excessive consumption of dairy products as they are high in calcium, which can interact with sodium citrate, leading to the formation of calcium oxalate stones in susceptible individuals.
• Staying well-hydrated with water is crucial, especially during rehydration therapy, to maintain fluid balance and support the function of sodium chloride and sodium citrate.
• Limit caffeine intake from coffee, tea, and energy drinks as it can impact hydration and potentially interact with the rehydration process.
• Avoid high-sugar foods and beverages as they can affect fluid balance and may not be recommended during rehydration therapy.
• Consider including foods with natural diuretic properties like cucumber, watermelon, and parsley to support fluid regulation.

Sodium chloride and sodium citrate sachets should be stored in a cool, dry area, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the sachets inside their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in hot environments like near stoves or inside bathrooms, as temperature fluctuations can impact their quality. Always adhere to the expiry date indicated on the packaging and properly dispose of any unused or expired sachets. Do not flush them or pour them down the drain; instead, consult a pharmacist or local waste disposal guidelines for safe disposal. Keep these sachets out of children's reach to prevent accidental ingestion.

Following are the quick tips for Sodium Chloride, Sodium Citrate Sachet:

• Mix the contents of the sachet thoroughly with the recommended amount of water.
• Ensure the solution is fully dissolved before consumption.
• Drink the entire solution to ensure you receive the full dose.
• Stay well-hydrated by drinking plenty of fluids throughout the day.
• Follow the prescribed dosage and duration as advised by your healthcare professional.
• If you experience any side effects, contact your doctor immediately.
• Store the sachets in a cool, dry place, away from direct sunlight.