RELENZA 20MG TAB

Zanamivir's mechanism of action involves inhibiting the activity of viral neuraminidase, an enzyme found on the surface of influenza viruses. By binding to neuraminidase, zanamivir prevents the release of newly formed virus particles from infected cells, thereby blocking the spread of the virus within the respiratory tract. It specifically targets the active site of neuraminidase, rendering it unable to cleave sialic acid residues from host cell receptors. This inhibition disrupts the virus's ability to detach from infected cells and infect new cells, effectively slowing down the replication and spread of the influenza virus.

Neuraminidase inhibitor

Tablet

The following are the uses of Zanamivir 20MG Tablet:

• Used for treating influenza (flu) in adults and children aged 7 years and older.
• Used to prevent the spread of flu after exposure, especially in high-risk individuals.
• Used to control flu symptoms such as fever, cough, and body aches.
• Used to shorten the duration of illness when taken within 48 hours of symptoms appearing.
• Used for individuals with asthma or chronic respiratory conditions who are susceptible to flu complications.
• Used as a supplementary treatment alongside vaccination to provide additional protection.
• Used to reduce the risk of flu-related hospitalizations and severe outcomes.

In the case of an overdose of Zanamivir 20MG Tablet, it is important to remain calm and take appropriate action. While the medication is generally well-tolerated, an excessive amount may lead to increased side effects. These can include respiratory issues, gastrointestinal discomfort, and, in rare cases, allergic reactions. If you suspect an overdose, contact a healthcare professional immediately. They will provide guidance and ensure that any necessary medical interventions are taken promptly to address the situation effectively.

In the case of a missed dose of Zanamivir 20MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the full benefits of the medication.

To use Zanamivir 20MG Tablet, inhale the contents of one blister as instructed by your healthcare provider, typically twice a day, by loading the blister into the inhaler device, piercing the blister, and breathing in slowly and deeply to ensure proper delivery of the medication into your lungs.

Following are the conditions/situations when Zanamivir 20MG Tablet should not be used:

• Should not be used in individuals with a known allergy to Zanamivir or any of its ingredients.
• Not suitable for individuals with severe breathing problems or chronic obstructive pulmonary disease (COPD).
• Contraindicated in patients with a history of severe allergic reactions or anaphylaxis.
• Should not be used in children under 7 years of age due to an increased risk of adverse effects.
• Not recommended for individuals with a history of asthma or other respiratory diseases.
• Avoid using it in patients with a history of heart disease or cardiovascular disorders.
• Not suitable for individuals who have difficulty taking inhaled medications.

The side effects of Zanamivir 20MG Tablet may include:

• Headache
• Dizziness
• Nausea and vomiting
• Diarrhea
• Muscle aches
• Fatigue
• Cough
• Nasal irritation

Following are the precautions and warnings for Zanamivir 20MG Tablet:

• This medication is intended for oral inhalation only and should not be swallowed or injected. Inhalation instructions should be followed carefully.
• Zanamivir is not a substitute for the flu vaccine. It is recommended to get the flu vaccine annually as advised by a healthcare professional.
• Patients with a history of respiratory diseases like asthma or chronic obstructive pulmonary disease (COPD) should use Zanamivir with caution, as it may exacerbate respiratory symptoms.
• Not recommended for individuals with a history of severe allergic reactions to milk proteins, as the powder formulation may contain lactose.
• Zanamivir should be used with caution in elderly patients, as they may be more susceptible to adverse effects.
• Not recommended for use in children under 7 years of age due to the potential risk of choking or inhalation issues.
• Patients with underlying medical conditions, such as heart disease, kidney disease, or diabetes, should use this medication under medical supervision.

Following are the drug interactions for Zanamivir 20mg Tablet:

• Concomitant use with live attenuated influenza vaccine may reduce the effectiveness of the vaccine, as zanamivir may inhibit viral replication needed for an immune response.
• Use with other antiviral medications, such as oseltamivir, may have an additive effect, increasing the risk of side effects but also enhancing antiviral activity.
• Zanamivir should be used with caution in combination with bronchodilators like salbutamol or theophylline, as it may cause additive respiratory side effects, including wheezing or difficulty breathing.
• Use with immunosuppressive drugs, such as corticosteroids, may alter the immune response, potentially reducing the effectiveness of zanamivir.
• Concomitant use with systemic corticosteroids may increase the risk of respiratory side effects such as bronchospasm or irritation, especially in patients with a history of asthma or chronic obstructive pulmonary disease (COPD).
• Caution is advised when using zanamivir in combination with other drugs that affect renal function, as the drug is primarily excreted by the kidneys, and renal impairment may lead to an increased risk of adverse effects.

Following are the food interactions for Zanamivir 20MG Tablet:

• Zanamivir should be taken with caution if you consume grapefruit or grapefruit juice. It may increase the drug concentration in the body due to the inhibition of CYP3A4 enzyme, potentially leading to an increased risk of side effects.
• Avoid alcohol consumption while taking Zanamivir as it may cause respiratory distress and worsen respiratory conditions.
• Dairy products like milk and yogurt should not be taken together with Zanamivir. Calcium, as well as iron and magnesium-rich foods, can decrease the absorption of Zanamivir.
• Foods high in fat content can affect the absorption of Zanamivir. It is best to take the medication on an empty stomach or 2 hours before or after a meal.
• Avoid caffeine-rich products as they may interfere with the medication's effectiveness, especially in patients with respiratory conditions.
• Vitamin C-rich foods might impact Zanamivir's effectiveness. Avoid high doses of vitamin C supplements during treatment.
• Always consult your healthcare provider for personalized advice regarding food interactions and the best time to take Zanamivir for optimal absorption and effectiveness.

Zanamivir 20MG Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication should be kept in its original packaging, tightly sealed to maintain its integrity. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in hot or humid environments like bathrooms or near heating appliances. Always check the expiration date, and if the medication is no longer needed or has expired, do not flush or pour it down the drain. Contact your pharmacist or healthcare provider for guidance on safe disposal methods to protect the environment and public health. Keep the tablets securely stored away from children to prevent accidental consumption.

Following are the quick tips for Zanamivir 20MG Tablet:

• Wash your hands before and after handling the medication to maintain hygiene.
• Inhale the medication exactly as prescribed by your healthcare provider.
• Follow the inhalation technique instructions provided with the device.
• Breathe in slowly and deeply to ensure proper medication delivery.
• Do not swallow the tablet; it is for inhalation only.
• Store the medication at room temperature, away from moisture and heat.
• Dispose of any unused or expired medication properly, as per local guidelines.