Relispa Fort (80mg) 20 Tablets

Drotaverine is a spasmolytic medication that primarily acts as a phosphodiesterase (PDE) inhibitor. Its mechanism of action involves increasing intracellular levels of cyclic adenosine monophosphate (cAMP) by inhibiting the breakdown of cAMP by PDE. This increased cAMP concentration leads to smooth muscle relaxation, particularly in the gastrointestinal and urinary tracts. Drotaverine selectively inhibits PDE4, which is predominantly found in smooth muscle, while having less effect on other PDE subtypes. By preventing the degradation of cAMP, drotaverine helps to maintain smooth muscle relaxation, reduce spasms, and alleviate pain associated with various gastrointestinal and urogenital disorders.

Drotaverine 80mg

Antispasmodic

Tablet

The following are the uses of Drotaverine 80mg Tablet:

• Used for relieving painful muscle spasms in the abdomen, intestines, and bladder.
• Used to treat menstrual pain and discomfort.
• Used in managing kidney or ureteric colic.
• Used to alleviate pain and discomfort during endoscopic procedures.
• Used for reducing abdominal pain and cramping associated with digestive issues.
• Used to relax smooth muscles and improve blood flow in certain conditions.
• Used as an anti-inflammatory agent to reduce inflammation in specific medical cases.

Follow these dosage instructions:

• Adult Dosage

The recommended daily dosage is 40mg. The maximum dose is 80mg/daily.

• Child Dosage

The child's dosage is 20mg daily orally.

In the case of an overdose of Drotaverine 80mg Tablets, it is important to recognize the signs and act promptly. Symptoms may include severe drowsiness, dizziness, and nausea. If an overdose is suspected, seek medical advice immediately. Prompt action can prevent potential complications and ensure appropriate treatment. It is crucial to store medications safely and out of reach of children to minimize the risk of accidental ingestion.

In the case of a missed dose of Drotaverine 80mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions based on your specific medical condition and treatment plan.

To take Drotaverine 80mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, as directed by your doctor, typically two to three times a day, or as prescribed based on your medical condition.

Following are the conditions when Drotaverine 80mg Tablet should not be used:

• Avoid if you have a known allergy or hypersensitivity to Drotaverine or any other ingredients in the formulation.
• Not recommended for individuals with severe kidney or liver impairment.
• Contraindicated in patients with gastrointestinal obstruction or perforation.
• Should not be used during active gastrointestinal bleeding.
• Not suitable for individuals with a history of heart or cardiovascular disease.
• Avoid if you have a history of obstructive uropathy (blockage in the urinary tract).
• Not recommended for patients with severe dehydration or electrolyte imbalance.
• Do not use if you have or have ever had a blockage in the intestines or any other condition that might affect the normal function of the intestines.

The side effects of Drotaverine 80mg Tablet may include:

• Dry mouth
• Headache
• Nausea and vomiting
• Diarrhea
• Skin rashes or itching
• Dizziness
• Palpitations
• Allergic reactions (rare)

Following are the precautions and warnings for Drotaverine 80mg Tablet:

• This medication should be used with caution in patients with liver or kidney disease, as it may require dosage adjustments.
• Drotaverine may cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Alcohol consumption should be avoided as it may increase the risk of side effects.
• Not recommended for children under 12 years of age unless prescribed by a doctor.
• Elderly patients may be more sensitive to the side effects, so monitoring is necessary.
• Inform your doctor if you have any heart conditions or if you are taking any other medications, as Drotaverine may interact with certain drugs.
• If you have a history of gastrointestinal obstruction or any other obstruction-related conditions, use this medication with caution.

Following are the drug interactions for Drotaverine 80mg Tablet:

• Alcohol may increase the sedative effects of Drotaverine, leading to impaired coordination and judgment.
• Anticoagulants like Warfarin may have their effect enhanced by Drotaverine, potentially increasing the risk of bleeding.
• Drotaverine can decrease the effectiveness of Antihypertensives, making blood pressure control more challenging.
• The risk of adverse effects may increase when combined with Anticholinergics, such as dry mouth, blurred vision, and constipation.
• Using Drotaverine with other muscle relaxants can result in enhanced muscle relaxation and potential respiratory depression.
• The sedative effects of other CNS depressants, such as Benzodiazepines, may be increased by Drotaverine, leading to excessive drowsiness.
• Anticonvulsants may have their metabolism affected by Drotaverine, potentially requiring dosage adjustments.

Following are the food interactions to consider with Drotaverine 80mg Tablet:

• Avoid grapefruit and grapefruit juice as they can influence the effectiveness of Drotaverine by altering its metabolism.
• Alcohol consumption should be minimized or avoided as it may increase the risk of side effects, particularly related to the central nervous system.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks might enhance the stimulant effects of Drotaverine, potentially causing restlessness and sleep disturbances.
• High-fat meals can slightly delay the absorption of Drotaverine, leading to a potential delay in the onset of its effects.
• Spicy foods, while not directly interacting with Drotaverine, can exacerbate gastrointestinal symptoms in some individuals.
• Dairy products, especially when consumed in large quantities, might decrease the absorption of Drotaverine due to the presence of calcium.
• Avoid excessive salt intake, as Drotaverine may cause sodium retention in some cases, affecting individuals with hypertension or heart problems.
• Ensure adequate hydration, as Drotaverine can sometimes cause mild dehydration due to its antispasmodic effects.

Drotaverine 80mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight and moisture. The tablets should be kept inside their original packaging, ensuring the container is tightly sealed to maintain their integrity and prevent contamination. It is crucial not to store the medication in hot or humid environments like bathrooms or near kitchen appliances, as temperature fluctuations can impact its effectiveness. Always check the expiration date, and if the tablets are no longer needed or have expired, proper disposal is essential. Do not dispose of them in household waste or pour them down the drain; instead, consult your pharmacist for guidance on safe disposal methods. Keep this medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Drotaverine 80mg Tablet:

• Take the tablet as directed by your doctor, typically 1-2 tablets three times a day.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• You can take it with or without food, but taking it with food may help if you experience stomach irritation.
• Maintain a consistent schedule by taking your doses at evenly spaced intervals.
• If you forget a dose, skip it and continue with the next scheduled dose. Do not double the dose.
• Inform your doctor if you have any known allergies before taking this medication.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.