Reol (18mg) 30 Tablets

Ropinirole 18mg Tablet primarily acts as a dopamine agonist, mimicking the effects of dopamine in the brain. It binds to dopamine receptors, particularly D2 and D3 subtypes, in various regions of the brain, including the nigrostriatal and mesolimbic pathways. By activating these receptors, ropinirole stimulates the same pathways that are normally activated by dopamine, which is a neurotransmitter involved in motor control and reward systems. This mechanism helps in treating Parkinson's disease by compensating for the deficiency of dopamine in the brain, improving motor function, and reducing symptoms such as tremors, stiffness, and slow movement. Additionally, ropinirole's action on dopamine receptors in the mesolimbic pathway may contribute to its effectiveness in managing restless legs syndrome by modulating the dopamine-mediated regulation of movement and sensory perception.

Dopamine agonist.

Tablet

The following are the uses of Ropinirole 18mg Tablet:

• Used for managing symptoms of Parkinson's disease, providing relief from motor fluctuations.
• Used to treat restless legs syndrome, reducing uncomfortable sensations and improving sleep.
• Used to alleviate involuntary movements and stiffness associated with various neurological conditions.
• Used to restore dopamine levels in the brain, improving overall movement and control.
• Used as a long-term treatment to enhance quality of life for Parkinson's patients.
• Used to minimize twitching and spasms, promoting smoother movements.
• Used to improve walking ability and reduce tremors, ensuring better daily functioning.

In the case of an overdose of Ropinirole 18mg tablets, individuals may experience symptoms such as severe nausea, dizziness, fainting, and even hallucinations. It is important to recognize that taking more than the prescribed dosage can lead to serious health complications. If an overdose is suspected, immediate action should be taken, including contacting a healthcare professional or seeking emergency medical assistance. Prompt treatment can help manage the adverse effects and ensure the patient's well-being.

In the case of a missed dose of Ropinirole 18mg Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to remind you to take your medication as prescribed. Always consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Ropinirole 18mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, without crushing, chewing, or breaking the tablet.

Following are the conditions when Ropinirole 18mg Tablet should not be used:

• Should not be taken by individuals with a known allergy or hypersensitivity to Ropinirole or any of its inactive ingredients.
• Not suitable for patients with severe kidney disease or end-stage renal disease.
• Contraindicated in patients with severe liver impairment or active liver disease.
• Should not be used in individuals with uncontrolled high blood pressure.
• Not recommended for patients with severe psychotic disorders or a history of severe mental health conditions.
• Must not be taken by patients with a history of severe heart disease or those at risk of fainting or dizziness.
• Contraindicated in patients with a history of severe gastrointestinal bleeding or ulcers.
• Should be avoided in patients with severe sleep disorders, such as narcolepsy or sleep apnea.

The side effects of Ropinirole 18mg Tablet may include:

• Dizziness and lightheadedness
• Nausea and vomiting
• Fatigue and drowsiness
• Leg cramps
• Headache
• Weight loss
• Behavioral changes, including compulsive behaviors

Following are the precautions and warnings for Ropinirole 18mg Tablet:

• Not recommended for individuals with severe liver or kidney impairment, as dosage adjustments may be necessary and close monitoring is advised.
• May cause dizziness and sleepiness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Elderly patients should be closely monitored, as they may be more susceptible to adverse effects such as hallucinations, confusion, and orthostatic hypotension.
• Should be used with caution in patients with cardiovascular disease, as it may cause a decrease in blood pressure.
• Not recommended for patients with severe psychotic disorders or a history of hallucinations, as it may exacerbate these conditions.
• Patients with a history of gastrointestinal bleeding or peptic ulcer disease should be monitored, as Ropinirole may increase the risk of these conditions.
• Pregnant and breastfeeding women should consult their healthcare provider before taking Ropinirole, as the risks and benefits should be carefully considered.

Following are the drug interactions for Ropinirole 18mg Tablet:

• It may interact with dopamine antagonists, such as antipsychotic medications, reducing the effectiveness of ropinirole.
• Alcohol can enhance the sedative effects of ropinirole, leading to increased drowsiness and impaired motor skills.
• The use of dopamine agonists like ropinirole with certain anti-nausea medications (e.g., metoclopramide) can result in increased dopamine activity and potential side effects.
• Caution is advised when combining ropinirole with medications that lower blood pressure, as it may further decrease blood pressure, potentially causing dizziness or lightheadedness.
• Ropinirole may interact with certain medications used for depression, such as selective serotonin reuptake inhibitors (SSRIs), and the combination may require dosage adjustments.
• It can increase the effects of sedatives and sleep medications, leading to excessive drowsiness.
• Concomitant use with certain medications that affect the metabolism of ropinirole, such as CYP1A2 inhibitors, may increase ropinirole levels in the body.

Following are the food interactions for Ropinirole 18mg Tablet:

• Alcohol should be avoided or limited during treatment with Ropinirole as it may cause excessive drowsiness and increase the risk of adverse effects.
• Grapefruit and grapefruit juice should be consumed with caution as they can influence the metabolism of the drug, potentially leading to increased levels of Ropinirole in the body.
• High-fat meals may slightly delay the absorption of Ropinirole, but this effect is not considered clinically significant.
• Caffeine intake should be monitored as it can exacerbate side effects such as nervousness, restlessness, and insomnia.
• Patients should maintain a balanced diet, as Ropinirole may cause weight changes in some individuals.
• Avoid excessive consumption of foods containing tyramine, such as aged cheeses, cured meats, and certain types of beer, as Ropinirole can potentially interact with tyramine and lead to increased blood pressure.
• Stay hydrated and ensure adequate fluid intake, as dehydration may affect the overall effectiveness of the medication.
• No specific food restrictions are necessary, but maintaining a consistent diet can help manage the medication's effects.

Ropinirole 18mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (68°F to 77°F or 20°C to 25°C). Keep the tablets in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial to place the medication out of reach of children and pets to prevent accidental ingestion. Always check the expiration date, and do not use the tablets if they appear damaged or discolored. When disposing of unused or expired ropinirole tablets, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for safe and environmentally friendly disposal methods.

Following are the quick tips for Ropinirole 18mg Tablet:

• Consult your doctor before starting this medication and discuss your medical history.
• Take the tablet as directed by your doctor, usually once or twice daily.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• You can take it with or without food, but taking it with food may help prevent nausea.
• Avoid consuming alcohol while on this medication as it may worsen side effects.
• Store the tablets at room temperature, away from moisture and direct sunlight.
• Regularly monitor your symptoms and inform your doctor of any changes or concerns.