Resgyl 60ml Syrup

Racecadotril, the active ingredient in Racecadotril Syrup/Suspension, acts as an enkephalinase inhibitor, primarily targeting enkephalinase in the brush border of the small intestine. This enzyme is responsible for the breakdown of endogenous enkephalins, which are natural peptides that play a role in reducing intestinal secretion and modulating intestinal motility. By inhibiting enkephalinase, racecadotril enhances the local analgesic effect of enkephalins in the intestinal lumen, reducing intestinal secretion and fluid accumulation. This mechanism helps to alleviate diarrhea by promoting fluid absorption and reducing the frequency and volume of loose stools. The selective action of racecadotril in the gastrointestinal tract contributes to its effectiveness in managing acute diarrhea.

Antidiarrheal

Suspension

The following are the uses of Racecadotril Syrup/Suspension:

• Used for treating acute diarrhea in infants, children, and adults.
• Used for reducing the duration and intensity of diarrhea symptoms.
• Used for controlling watery diarrhea by reducing intestinal secretion.
• Used as an adjunct to oral rehydration therapy to enhance recovery.
• Used for managing diarrhea associated with gastrointestinal infections.
• Used to relieve diarrhea-related discomfort and improve patient well-being.
• Used as an alternative for patients intolerant to other antidiarrheal medications.
• Used for its antisecretory mechanism, targeting fluid and electrolyte loss.

In the case of an overdose of Racecadotril Syrup/Suspension, it is important to recognize the potential symptoms. These may include gastrointestinal discomfort, nausea, and in severe cases, diarrhea or vomiting. If an overdose is suspected, seeking medical advice promptly is recommended. Quick action can help mitigate any adverse effects and ensure appropriate treatment is provided to manage the overdose effectively. This is crucial for the well-being of the patient.

In the case of a missed dose of Racecadotril Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. For children, consult a healthcare professional for guidance on how to handle missed doses, as the dosage may need to be adjusted based on their age and weight.

To administer Racecadotril Syrup/Suspension, shake the bottle well, measure the prescribed dose with an oral syringe or measuring cup, and give it orally, typically 3 times a day or as directed by your healthcare provider, regardless of meals.

Here are the conditions and situations when Racecadotril Syrup/Suspension should not be used:

• Not suitable for patients with known hypersensitivity or allergy to Racecadotril or any of the excipients in the syrup/suspension.
• Contraindicated in patients with severe renal impairment (kidney disease).
• Should not be used in patients with acute pancreatitis.
• Not recommended for patients with a history of gastrointestinal obstruction or severe constipation.
• Avoid using in patients with active ulcerative colitis or Crohn's disease.
• Not suitable for infants under 3 months of age due to limited data on safety and efficacy.
• Contraindicated during breastfeeding as it may pass into breast milk.

The side effects of Racecadotril Syrup/Suspension may include:

• Nausea or vomiting
• Abdominal pain or discomfort
• Constipation
• Dry mouth
• Headache
• Dizziness or lightheadedness
• Skin rash or itching
• Swelling or redness of the skin
• Allergic reactions, including angioedema
• Fever or chills (rare)
• Respiratory symptoms such as cough or nasal congestion (rare)

Following are the precautions and warnings for Racecadotril Syrup/Suspension:

• Racecadotril should not be used in patients with known hypersensitivity or allergy to the drug or any of its components.
• This medication is not recommended for patients with severe kidney or liver disease, as it may require dosage adjustments.
• Caution is advised for patients with moderate kidney or liver impairment, and regular monitoring is necessary.
• Racecadotril should be used with caution in the elderly, as they may be more susceptible to its effects and side effects.
• Do not exceed the recommended dosage, as it may lead to increased adverse effects.
• Patients with a history of gastrointestinal disorders should use this medication with caution and under medical supervision.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as its safety during pregnancy and lactation is not fully established.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Racecadotril Syrup/Suspension:

• It may reduce the absorption of other medications due to its antisecretory effect, particularly affecting drugs like phenytoin, ketoconazole, and atazanavir.
• Concomitant use with other antidiarrheal drugs like loperamide can increase the risk of constipation.
• Racecadotril can interact with antibiotics, especially oral quinolones, potentially reducing their effectiveness.
• The effectiveness of oral contraceptives may be decreased when taken with Racecadotril.
• It may increase the concentration of digoxin, requiring close monitoring of digoxin levels.
• Use with angiotensin-converting enzyme (ACE) inhibitors can lead to increased potassium levels in the blood.
• Caution is advised when combining with diuretics, as it may affect electrolyte balance.

Following are the food interactions for Racecadotril Syrup/Suspension:

• Avoid consuming high-fat meals while taking this medication as it can decrease the absorption and effectiveness of Racecadotril.
• Consuming grapefruit or grapefruit juice should be avoided as it may interfere with the metabolism of the drug, leading to increased levels in the body and potential side effects.
• Alcohol intake is not recommended as it may increase the risk of gastrointestinal side effects and may also impair the effectiveness of the medication.
• Dairy products like milk and cheese might reduce the absorption of Racecadotril, so it's best to separate them by a few hours.
• Avoid spicy foods as they can potentially irritate the digestive system and reduce the efficacy of the medication.
• Consume high-fiber foods like whole grains, fruits, and vegetables to promote healthy digestion and support the medication's effect.
• Always ensure an adequate fluid intake to maintain hydration, especially if experiencing diarrhea.
• Certain foods rich in vitamins and minerals, such as bananas, potatoes, and oral rehydration solutions, can help replenish electrolytes lost during diarrhea.

Racecadotril Syrup/Suspension should be stored in a secure location, away from direct sunlight, moisture, and extreme temperatures. Maintain the medication at room temperature, ensuring it remains in its original container with the cap tightly sealed to prevent contamination. It's crucial not to store it in bathrooms or near heat-emitting appliances to preserve its integrity. Prior to administration, verify the expiration date on the packaging, and if the medication is past its prime or no longer needed, do not dispose of it via toilet flushing or drainage systems. Instead, consult a pharmacist or healthcare professional for guidance on appropriate disposal methods. Additionally, ensure the medication is kept out of children's reach to prevent accidental consumption.

Following are the quick tips for Racecadotril Syrup/Suspension:

• Consult a doctor for proper dosage and duration based on your medical condition.
• Administer the syrup/suspension as directed by your physician for best results.
• Measure the dose accurately using the measuring cup provided.
• Store it at room temperature, away from excessive heat and moisture.
• Keep the medication out of children's reach to prevent accidental consumption.
• Avoid sharing this medication with others, even if they have similar symptoms.
• Inform your doctor about any other medications you are taking to ensure safe use.
• Do not freeze the syrup/suspension.