RESPIRATE E 60ML SYP

Salbutamol, a key component of the syrup/suspension, acts as a selective beta-2 adrenergic receptor agonist. When administered, it binds to these receptors in the lungs, leading to relaxation of the smooth muscles surrounding the airways. This mechanism is pivotal in inducing rapid bronchodilation, effectively alleviating bronchospasm and reducing airway resistance. Alongside salbutamol, Guaifenesin, an expectorant, facilitates the process by thinning and loosening mucus in the airways, thereby enhancing the clearance of bronchial secretions. This dual action provides symptomatic relief and aids in the management of respiratory conditions characterized by excessive mucus production and airway constriction.

Bronchodilator, Expectorant

Suspension

The following are the uses of Salbutamol, Guaifenesin Syrup/Suspension:

• Used for relieving coughs and chest congestion associated with respiratory illnesses like the common cold, bronchitis, and asthma.
• Used to relax the muscles around the airways, making breathing easier for individuals with asthma or chronic obstructive pulmonary disease (COPD).
• Used to reduce wheezing, shortness of breath, and tightness in the chest.
• Used for breaking up and loosening mucus in the airways, allowing for easier coughing and clearing of the chest.
• Used to prevent and manage exercise-induced bronchoconstriction, enabling asthmatic individuals to engage in physical activities more comfortably.
• Used to provide quick relief during asthma attacks, helping to open up the airways and restore normal breathing.
• Used for long-term management of asthma symptoms, often in combination with other controller medications.

In the case of an overdose of Salbutamol, symptoms may include rapid heart rate, tremors, nervousness, and headache. For Guaifenesin Syrup, an overdose can lead to nausea, vomiting, dizziness, and an upset stomach. If an overdose is suspected, seek medical advice promptly. Treatment involves managing symptoms and providing supportive care. It is important to keep medications out of reach of children to prevent accidental ingestion.

In the case of a missed dose of Salbutamol, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. For Guaifenesin Syrup/Suspension, if a dose is missed, take it as soon as possible, but if it is near the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

To administer Salbutamol and Guaifenesin Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and take it orally, preferably at evenly spaced intervals, as directed by your healthcare professional.

Following are the conditions/situations when Salbutamol, Guaifenesin Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy to Salbutamol, Guaifenesin, or any of the excipients in the suspension.
• Contraindicated in patients with a history of hypersensitivity or severe reactions to sympathomimetic amines.
• Not recommended for patients with severe cardiovascular disorders, including severe hypertension, coronary artery disease, or recent heart attack.
• Should not be used in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Contraindicated in patients with narrow-angle glaucoma.
• Not suitable for individuals with a history of peptic ulcer disease or those who are currently experiencing a peptic ulcer.
• Should be avoided in patients with diabetes, as it may increase blood glucose levels.
• Not recommended for patients with hyperthyroidism.

The side effects of Salbutamol, Guaifenesin Syrup/Suspension may include:

• Nervousness or tremors
• Headache
• Nausea or vomiting
• Dry mouth or throat irritation
• Dizziness
• Rapid heart rate (tachycardia)
• Insomnia
• Muscle cramps

Following are the precautions and warnings for Salbutamol, Guaifenesin Syrup/Suspension:

• This medication should not be used by individuals with a known allergy to salbutamol, guaifenesin, or any other ingredients in the syrup.
• Patients with a history of heart problems, high blood pressure, diabetes, or seizures should use this medication with caution and under medical supervision.
• It may cause nervousness, restlessness, or insomnia, so individuals with anxiety disorders should exercise caution.
• Avoid driving or operating heavy machinery until you know how this medication affects you, as it may cause dizziness.
• Consult a doctor if you have a persistent cough, as this medication is intended for short-term use.
• Do not exceed the recommended dosage, as excessive use can lead to serious side effects.
• Keep out of reach of children, and store in a cool, dry place.
• Inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.

Following are the drug interactions for Salbutamol, Guaifenesin Syrup/Suspension:

• May interact with other bronchodilators (e.g., theophylline, other beta-agonists) and increase the risk of cardiovascular side effects.
• Using non-potassium-sparing diuretics with Salbutamol may lower potassium levels.
• Monoamine oxidase inhibitors (MAOIs) can interact, potentially causing hypertension.
• Beta-blockers may reduce the effects of Salbutamol.
• Antihistamines and other cough/cold medications may have additive effects on the cardiovascular system.
• Xanthine derivatives like theophylline may increase cardiovascular and central nervous system side effects.
• Salbutamol may decrease the effectiveness of Beta-blockers and Anticholinesterases.

Following are the food interactions for Salbutamol, Guaifenesin Syrup/Suspension:

• Grapefruit juice should be used cautiously as it may increase the concentration of Salbutamol in the blood, potentially leading to increased side effects.
• Avoid consuming large amounts of caffeine-containing foods and beverages (e.g., coffee, tea, colas, chocolate) as it may increase side effects such as nervousness, shakiness, and rapid heartbeat.
• Consuming alcohol may increase the risk of side effects such as dizziness, drowsiness, and lightheadedness, especially in children.
• Guaifenesin may be taken with or without food, but taking it with food can help prevent gastrointestinal upset.
• Avoid eating large, heavy meals as it may interfere with the absorption of the medication, especially if it is taken in syrup/suspension form.
• Certain foods like chocolate, cheese, and processed meats should be consumed in moderation as they may interact with the medication's effectiveness.
• It is advisable to maintain a balanced diet and stay well-hydrated to support the medication's efficacy and overall health.

Salbutamol and Guaifenesin Syrup/Suspension should be stored in a cool, dry area, ideally between 68°F and 77°F (20°C and 25°C), ensuring it remains protected from direct sunlight and moisture. Keep the medication securely sealed in its original packaging to maintain its integrity and prevent contamination. Avoid placing it in the bathroom or near heat-emitting appliances like ovens or heaters, as extreme temperatures can impact its effectiveness. Dispose of any unused or expired medication responsibly; refrain from flushing it down the toilet or pouring it into drainage systems. Instead, consult a pharmacist or healthcare professional for appropriate disposal guidelines. Lastly, ensure the medication is stored safely away from children to prevent accidental ingestion.

Following are the quick tips for Salbutamol, Guaifenesin Syrup/Suspension:

• Always follow the prescribed dosage and frequency provided by your doctor.
• Shake the bottle thoroughly before each use to ensure proper medication distribution.
• Administer the syrup with a glass of water, avoiding tea, coffee, or dairy products for better absorption.
• Maintain a consistent schedule by taking the medication at the same time daily.
• If stomach discomfort occurs, consider taking it with food or after meals for relief.
• Store the syrup in a secure location, out of children's reach, to prevent accidental ingestion.
• Do not share your medication with others, even if their symptoms appear similar.
• Consult your healthcare provider if symptoms persist or worsen despite medication.