Revoban (2.5mg) 14 Tablets

Rivaroxaban, at a dosage of 2.5mg, exerts its anticoagulant effect by selectively inhibiting factor Xa, a key enzyme in the coagulation cascade. This mechanism disrupts the conversion of prothrombin to thrombin and subsequently interferes with the formation of fibrin clots. By blocking factor Xa, rivaroxaban effectively prevents the development of blood clots, thereby reducing the risk of thromboembolic events. This targeted action on factor Xa distinguishes rivaroxaban from other anticoagulants, providing a specific and controlled approach to anticoagulation therapy.

Anticoagulant.

Tablet

The following are the uses of Rivaroxaban 2.5mg Tablet:

• Used for preventing blood clots in patients after knee or hip replacement surgeries, reducing the risk of deep vein thrombosis (DVT).
• Used for treating pulmonary embolism (blood clot in the lungs) and preventing recurrent clots.
• Used for reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
• Used for long-term treatment to prevent blood clots in patients with a history of DVT or pulmonary embolism.
• Used for managing acute coronary syndrome (reduced blood flow to the heart) in combination with other medications.
• Used for preventing blood clots in patients with limited mobility due to medical conditions.
• Used for reducing the risk of blood clots in patients with cancer and undergoing chemotherapy.
• Used for preventing venous thromboembolism (VTE) in acutely ill hospitalized medical patients.

Follow these dosage instructions:

• Adult Dosage

10 milligrams (mg) once a day. Your doctor will determine the length of the treatment.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

In the case of an overdose of Rivaroxaban 2.5mg tablets, it is important to recognize the potential severity of this situation. Symptoms may include excessive bleeding, easy bruising, and prolonged bleeding from wounds. Prompt medical intervention is necessary, as doctors may administer a specific antidote called andexanet alfa to counteract the effects of the overdose. Immediate medical attention should be sought, and the patient should be closely monitored for any signs of internal bleeding or other complications.

In the case of a missed dose of Rivaroxaban 2.5mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice, as they may recommend adjusting your dosing schedule or provide specific instructions to ensure the medication's effectiveness. It is generally best to take the medication at the same time each day to maintain consistent blood levels.

To take Rivaroxaban 2.5mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your doctor, usually once daily with or without food.

Following are the conditions when Rivaroxaban 2.5mg Tablet should not be used:

• Do not take this medication if you have an active or uncontrolled bleeding disorder.
• Avoid if you have a history of recent bleeding in the brain or spinal column.
• Not suitable for individuals with severe kidney disease or end-stage kidney disease.
• Should not be used if you have a known allergy to Rivaroxaban or any of the inactive ingredients in the tablet.
• Contraindicated in patients with mechanical prosthetic heart valves.
• Avoid if you are currently undergoing spinal anesthesia or lumbar puncture.
• Do not take this medication if you have a planned surgery or procedure involving the brain, spine, or eyes.
• Not recommended for individuals with severe uncontrolled high blood pressure.

The side effects of Rivaroxaban 2.5mg Tablet may include:

• Increased risk of bleeding (may include nosebleeds, bleeding gums, unusual bruising, coughing up blood)
• Easy bruising
• Skin rash or itching
• Weakness or fatigue
• Dizziness or lightheadedness
• Headache
• Nausea and vomiting
• Stomach pain or discomfort

Following are the precautions and warnings for Rivaroxaban 2.5mg Tablet:

• This medication should not be used in patients with active pathological bleeding or a history of bleeding diathesis, including but not limited to hemophilia or other bleeding disorders.
• Patients with a history of hypersensitivity or allergic reactions to Rivaroxaban or any of its components should not take this medication.
• Rivaroxaban may increase the risk of bleeding, including intracranial and fatal bleeding. Patients should be monitored for any signs of bleeding and seek immediate medical attention if unusual bleeding occurs.
• Caution is advised in patients with liver disease, as Rivaroxaban is primarily metabolized in the liver. Regular liver function tests may be required.
• Elderly patients may be at higher risk of bleeding complications, and dose adjustments might be necessary based on kidney function.
• Patients undergoing spinal procedures or spinal anesthesia are at risk of developing hematomas. The risk increases with the use of indwelling epidural catheters or the use of medications affecting hemostasis.
• Rivaroxaban should be used with caution in patients with renal impairment, and dosage adjustments may be required based on the severity of the condition.
• This medication may cause an increased risk of thrombotic events, including deep vein thrombosis and pulmonary embolism, if treatment is discontinued prematurely or if the patient has underlying risk factors.

Following are the drug interactions for Rivaroxaban 2.5mg Tablet:

• Ketoconazole, Itraconazole, Ritonavir, and Cobicistat can increase Rivaroxaban levels, potentially leading to increased bleeding risk.
• Rifampin, Carbamazepine, and Phenytoin may decrease the effectiveness of Rivaroxaban by reducing its levels.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen and Naproxen can increase the likelihood of bleeding when used with Rivaroxaban.
• Herbal supplements such as St. John's Wort may reduce Rivaroxaban levels and its anticoagulant effect.
• Antiplatelet agents including Clopidogrel and Aspirin enhance the risk of bleeding when combined with Rivaroxaban.
• Some antibiotics like Clarithromycin and Erythromycin can increase Rivaroxaban concentrations.
• Caution is advised with medications affecting CYP3A4 and P-gp, as they may alter Rivaroxaban's metabolism and transport.

Following are the food interactions for Rivaroxaban 2.5mg Tablet:

• Avoid consuming grapefruit and grapefruit juice as they can increase the drug's concentration in the blood, potentially affecting blood clotting.
• Alcohol intake should be limited as it can increase the risk of bleeding complications.
• High-fat meals may affect the absorption of Rivaroxaban, so it is advisable to maintain a consistent diet pattern.
• Vitamin K-rich foods like leafy greens may reduce the drug's effectiveness, so consult your doctor about dietary adjustments.
• Avoid cranberry juice as it can potentially interact with Rivaroxaban and affect its blood-thinning properties.
• Certain herbal supplements, such as St. John's Wort, may influence the drug's metabolism and should be used with caution.
• Always inform your healthcare provider about your dietary habits to ensure the safe and effective use of Rivaroxaban.
• Maintain a balanced diet and follow any dietary recommendations provided by your doctor or pharmacist.

Rivaroxaban 2.5mg Tablets should be stored in a secure and dry location, away from direct sunlight, moisture, and heat sources like radiators or stoves, as these conditions can degrade the medication's quality. The tablets should be kept in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to regularly check the expiration date on the package, and any unused or expired tablets should be disposed of responsibly. Do not flush the medication down the toilet or pour it into drains; instead, consult a pharmacist or healthcare professional for appropriate disposal methods to minimize environmental impact. Always keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Rivaroxaban 2.5mg Tablet:

• Consult your doctor before starting this medication, especially if you have kidney or liver problems.
• Take the tablet with a full glass of water, preferably with food.
• Do not break, crush, or chew the tablet; swallow it whole.
• Maintain a consistent dosing schedule; take it at the same time each day.
• Inform your doctor about all medications you're taking to prevent potential interactions.
• Regular blood tests may be required to monitor your liver function and blood clotting.
• Contact your doctor immediately if you experience any unusual bleeding or bruising.