RHINOLAST NASAL APRAY 22ML IMP

Azelastine spray, a commonly used nasal medication, exerts its therapeutic effects through selective antagonism of histamine H1 receptors. By blocking these receptors, azelastine effectively inhibits the release of histamine and other pro-inflammatory mediators from mast cells and basophils. This mechanism plays a crucial role in alleviating symptoms associated with allergic rhinitis, such as sneezing, itching, and nasal congestion. The spray's localized action helps to reduce inflammation in the nasal passages, providing relief from the discomfort caused by allergic reactions.

Antihistamine nasal spray.

Spray

The following are the uses of Azelastine Spary:

• Used for relieving symptoms of seasonal allergic rhinitis, like sneezing, runny nose, and itching.
• Used for treating allergic reactions in the eyes, such as redness, itching, and watering.
• Used for managing symptoms of indoor allergies, including pet dander and dust mites.
• Used to reduce nasal congestion and post-nasal drip caused by allergies.
• Effective for providing quick relief from allergy-induced nasal discomfort.
• Used to prevent allergy symptoms before exposure to known triggers.

In the case of an overdose of Azelastine Spray, it is important to recognize the signs and act promptly. Symptoms may include increased drowsiness, fatigue, and dizziness. If you suspect an overdose, immediately contact a healthcare professional or a poison control center for guidance. They will provide specific instructions to manage the situation effectively, which may include monitoring vital signs and providing supportive care until the effects of the medication wear off.

In the case of a missed dose of Azelastine Spray, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your medication routine. It is important to maintain consistency with this medication for optimal effectiveness.

To use Azelastine Nasal Spray, gently blow your nose to clear any congestion, then tilt your head slightly forward, insert the nasal applicator into one nostril, and press the pump while breathing in gently through your nose to release the spray.

Following are the conditions or circumstances when Azelastine Spray should be avoided:

• Not suitable for individuals with a known allergy or hypersensitivity to Azelastine or any of the spray's components.
• Should not be used if you have recently undergone nasal surgery or have untreated nasal infections.
• Contraindicated in individuals with severe nasal septum deviations, as it may affect the spray's effectiveness.
• Avoid using it if you have a history of nasal ulcers or recent nasal trauma.
• Not recommended for children below a certain age (usually 5 or 6 years), as its safety and efficacy may not be established in younger children.
• Avoid spraying into the eyes or on broken skin.
• Should not be shared with others to prevent the risk of cross-infection.

The side effects of Azelastine Nasal Spray may include:

• Bitter taste in the mouth
• Headache
• Nasal irritation or dryness
• Fatigue or drowsiness
• Sore throat
• Runny nose or nasal congestion
• Sneezing
• Burning or itching in the nose

Following are the precautions and warnings:

• Azelastine Spray is for nasal use only and should not come into contact with the eyes. Avoid spraying it towards the eyes or swallowing the medication.
• This medication should not be used by individuals with a known allergy to Azelastine or any of its ingredients.
• If you have a history of nasal surgery or injuries, consult your healthcare provider before using this spray, as it may affect its effectiveness.
• Caution is advised in patients with a history of nasal dryness or irritation, as Azelastine may cause further dryness or irritation.
• Avoid using Azelastine with other nasal medications without consulting your healthcare provider to prevent potential drug interactions.
• Do not share your nasal spray with others, as it is intended for personal use and may spread infections.
• If symptoms persist or worsen after using Azelastine for several days, discontinue use and consult a healthcare professional.
• Store Azelastine Spray at room temperature, away from direct sunlight and moisture, and keep it out of reach of children.

Following are the drug interactions for Azelastine Spray:

• Azelastine may cause drowsiness when taken with other medications that have a sedative effect, such as benzodiazepines, opioids, or antihistamines.
• Avoid using Azelastine with other nasal sprays or decongestants, as it may lead to increased side effects or reduced efficacy.
• The effects of alcohol may be enhanced when consumed with Azelastine, potentially causing increased drowsiness and impaired thinking.
• Certain antidepressants (e.g., SSRIs, tricyclic antidepressants) can interact with Azelastine, leading to increased sedation and impaired alertness.
• Azelastine may have additive effects when used with other antihistamines, increasing the risk of side effects like dry mouth, blurred vision, and urinary retention.
• It may interact with drugs that affect the liver's enzyme system, such as azole antifungals or macrolide antibiotics, potentially altering Azelastine's metabolism.
• Caution is advised when using Azelastine with blood pressure medications, as it may cause a slight increase in heart rate and blood pressure in some individuals.

Following are the food interactions to consider with Azelastine Spray:

• Avoid consuming alcohol as it may increase the risk of drowsiness and dizziness as a side effect of the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the enzyme CYP3A4, potentially leading to increased Azelastine levels in the body.
• Hot and spicy foods are best avoided as they may trigger or exacerbate symptoms of rhinitis or allergic reactions.
• Dairy products like milk or yogurt may be beneficial to consume alongside Azelastine, as they can help coat the throat and reduce irritation caused by the spray.
• Foods rich in vitamin C, such as citrus fruits and broccoli, may provide additional anti-inflammatory benefits and support the immune system.
• Staying well-hydrated by drinking plenty of water can help thin mucus and reduce congestion, enhancing the effectiveness of Azelastine.
• A balanced diet with a variety of fruits, vegetables, whole grains, and lean proteins can contribute to overall health and potentially reduce the severity of allergic responses.
• Avoid caffeine-rich beverages like coffee or energy drinks, as they may dehydrate the body and potentially worsen symptoms.

Azelastine Spray should be stored with utmost care to maintain its effectiveness and safety. Keep the spray bottle in a cool and dry place, preferably at room temperature, ensuring it is away from direct sunlight, heat, or moisture-prone areas like bathrooms. It is crucial to store the medication in its original packaging, tightly sealed, to prevent contamination. Always check the expiration date, and never use the spray beyond its expiry. When it's time to discard the medication, do not flush or pour it down the drain. Instead, consult your pharmacist or local waste disposal company for safe and environmentally friendly disposal methods. Keep the spray out of children's reach to prevent accidental exposure.

Following are the quick tips for Azelastine Spray:

• Wash your hands before using the spray to maintain hygiene.
• Shake the bottle gently before each use to ensure proper mixing.
• Prime the spray if you're using it for the first time or after a period of non-use.
• Tilt your head slightly forward and insert the nozzle into one nostril.
• Spray the prescribed number of times while breathing gently through your nose.
• Alternate nostrils for each dose to ensure even distribution.
• Avoid blowing your nose immediately after using the spray for better effectiveness.
• Store the spray at room temperature, away from direct sunlight and moisture.