Rhulef (10mg) 30 Tablets

This medicine is used as a pain management treatment for Arthritis. It contains Leflunomide, a disease-modifying Antirheumatic Drug, that works by stopping the body from producing too many of the immune cells that are responsible for swelling and inflammation.

Leflunomide 10mg

Disease-modifying Antirheumatic Drugs (DMARDs)

Tablet

Leflunomide is utilized for the following therapeutic indications:

• Treatment of active rheumatoid arthritis to reduce signs and symptoms
• Disease-modifying antirheumatic drug (DMARD) that slows the progression of joint damage
• May be used in the management of psoriatic arthritis
• Helps improve physical function in patients with arthritis

Follow these dosage instructions:

• Adult Dosage

For patients who are at a low risk for liver disease, start with 100mg once daily for 3 days, then 20mg once daily.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

Overdose symptoms include vomiting, diarrhea, gastrointestinal bleeding, severe bone marrow suppression, disturbance of liver function, etc. Seek emergency medical help if you think you have taken too much of this medicine.

If you miss a dose, make sure to take it as soon as possible the same day. If you don't remember missing the dose, don't double it. Consult your doctor on how to adjust the missing doses.

Take one tablet per day, with or without food as your doctor has recommended. Swallow the tablet with water and don't chew it. Take the medication regularly and at the same time each day to get the most benefit from it.

This medication should not be used by the patients with:

• Severe Immunodeficiency (weak immune system)
• Bone marrow dysfunction
• Blood dyscrasias (diseases of blood)
• Hepatic (liver) and Renal (kidney) insufficiency
• Ulcerative stomatitis (ulcers in mouth)
• Hypoproteinemia (low protein level in blood)

Common side effects include:

• Loss of appetite
• Feeling or being sick
• Stomach pain or indigestion
• Diarrhea
• Headaches
• Feeling tired or drowsy
• Hair loss

You should understand these cautions before taking the medicine:

• Talk to your doctor if you have hypersensitivity or allergic reactions to any of the components in the medicine.
• Consult with your doctor if you are pregnant, or a lactating mother.
• Talk to your doctor if you have liver or kidney disease.
• Don’t drink alcohol and don’t drive while taking this medication.
• Contraception must be used by both men and women during and till 2 years after use of the drug.

This medication may interact with drugs like:

• Acitretin
• Asparaginase
• Chloramphenicol
• Leflunomide
• Other drugs that can cause kidney problems (such as cisplatin)
• Other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin)
• Penicillins
• Phenytoin
• Probenecid
• Procarbazine
• Pyrimethamine
• Sulfa medications
• Tetracyclines.

Store the medicine at room temperature and keep out of direct sunlight, excessive heat, and moisture. Keep the medicine out of the reach of children and animals. Do not use the medication past its expiration date.

No

Always follow your doctor's advice, and never self-medicate.