Roxyzin (25mg) 50 Tablets

Hydroxyzine HCl 25mg tablets primarily exert their effects through potent antagonism of histamine H1 receptors. By blocking these receptors, hydroxyzine effectively competes with histamine for receptor binding, thereby inhibiting the action of histamine. This mechanism is responsible for its antihistamine properties, reducing histamine-induced symptoms such as itching, hives, and nasal congestion. Moreover, hydroxyzine's anxiolytic and sedative effects are believed to be linked to its ability to inhibit histamine release in the central nervous system, which subsequently influences other neurotransmitter systems, leading to relaxation and reduced anxiety.

Hydroxyzine Hcl 25mg

Antihistamine.

Tablet

The following are the uses of Hydroxyzine Hcl 25mg Tablet:

• Used for relieving anxiety and tension, especially before surgeries or stressful events.
• Used to treat symptoms of allergic reactions, such as itching and hives.
• Used for short-term treatment of insomnia and sleep disturbances.
• Effective in reducing nausea and motion sickness.
• Helps manage symptoms of eczema and skin allergies.
• Used to provide pre• and post-operative sedation.
• Can aid in the management of certain psychiatric disorders.

In the case of an overdose of Hydroxyzine HCL 25mg tablets, individuals may experience severe drowsiness, confusion, and an increased heart rate. Other symptoms can include dizziness, blurred vision, and difficulty in breathing. It is important to recognize that an overdose can lead to more serious complications, such as seizures, fainting, or even a coma. Prompt medical intervention is necessary to manage these symptoms and prevent potential long-term health consequences.

In the case of a missed dose of Hydroxyzine Hcl 25mg Tablet, it is generally advised to take the missed dose as soon as you remember, provided it is not too close to the time of your next scheduled dose. If it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. However, do not double the dose to make up for a missed one, as this may increase the risk of side effects. It's important to maintain a consistent medication routine, and if you frequently miss doses, consult your healthcare provider for guidance on managing your medication schedule effectively.

To take Hydroxyzine Hcl 25mg Tablets, swallow the tablet whole with a glass of water, preferably with or after a meal, once or twice a day as directed by your healthcare provider, ensuring you follow the prescribed dosage and duration of treatment.

Here are the conditions or situations when Hydroxyzine HCl 25mg Tablet should not be taken:

• Allergy Should not be used in patients with a known allergy or hypersensitivity to Hydroxyzine HCl or any of its inactive ingredients.
• Liver Impairment Not recommended for patients with severe liver impairment as it may lead to increased side effects.
• Pregnancy Contraindicated in pregnant women, especially during the first trimester, unless the potential benefits outweigh the risks.
• Breastfeeding Should be avoided by breastfeeding mothers as it can pass into breast milk and may cause harm to the nursing infant.
• Elderly Use with caution in elderly patients as they may be more sensitive to the side effects, especially dizziness and sedation.
• Glaucoma Not suitable for patients with narrow-angle glaucoma.
• Prolonged QT Interval Hydroxyzine HCl should be avoided in patients with a prolonged QT interval or heart rhythm disorders.
• Seizure Disorders Use with caution in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Bladder Obstruction Should not be used in patients with bladder or urinary retention issues.
• Central Nervous System (CNS) Depression Contraindicated in patients with CNS depression or those taking other CNS depressants, as it can enhance the sedative effects.

The side effects of Hydroxyzine Hcl 25mg Tablet may include:

• Drowsiness or sedation
• Dry mouth
• Blurred vision or dizziness
• Constipation
• Nausea or vomiting
• Fatigue or weakness
• Skin rash or itching
• Difficulty in urination

Following are the precautions and warnings for Hydroxyzine Hcl 25mg Tablet:

• Not suitable for individuals with a known allergy to Hydroxyzine or similar antihistamines.
• May cause drowsiness and affect mental alertness; avoid driving or operating machinery until the effects are known.
• Alcohol consumption should be avoided as it may intensify the sedative effects.
• Elderly patients may be more sensitive to the side effects, especially dizziness and confusion.
• Patients with liver or kidney problems should use with caution and under medical supervision.
• Not recommended for children below 6 years of age without medical advice.
• Consult a doctor if pregnant, planning to become pregnant, or breastfeeding before using this medication.

Following are the drug interactions for Hydroxyzine Hcl 25mg Tablet:

• Alcohol and other central nervous system (CNS) depressants, such as opioids or benzodiazepines, can increase sedation and respiratory depression.
• Monoamine oxidase inhibitors (MAOIs) should be avoided due to increased risk of severe adverse reactions.
• Hydroxyzine may potentiate the effects of anticholinergic drugs, leading to increased side effects.
• Concomitant use with other antihistamines may result in additive drowsiness and sedation.
• Drugs metabolized by CYP450 enzymes, especially CYP3A4, may have altered metabolism when taken with Hydroxyzine.
• Anticonvulsants like phenytoin may have decreased efficacy when used with Hydroxyzine.
• Antipsychotics and tricyclic antidepressants may enhance the sedative effects of Hydroxyzine.

Following are the food interactions for Hydroxyzine Hcl 25mg Tablet:

• Alcohol consumption should be avoided as it may increase the sedative effects of Hydroxyzine, leading to enhanced drowsiness and dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of Hydroxyzine, potentially leading to increased side effects.
• High-fat meals can delay the absorption of Hydroxyzine, possibly reducing its effectiveness.
• Caffeinated beverages should be limited as they can counteract the calming effects of Hydroxyzine, making it less effective for anxiety or sleep disorders.
• Avoid spicy foods as they may exacerbate stomach irritation, a known side effect of Hydroxyzine.
• Avoid excessive salt intake as Hydroxyzine may cause water retention, and a high-sodium diet can worsen this effect.
• Ensure adequate fluid intake as Hydroxyzine can cause dry mouth and dehydration.
• It is generally advisable to take Hydroxyzine with a meal or a light snack to minimize gastrointestinal side effects.

Hydroxyzine HCL 25mg tablets should be stored in a cool, dry area, preferably at room temperature, and protected from light and moisture. The original container should be used to safeguard the tablets from contamination and to ensure proper identification. It is crucial not to store them in the bathroom or near heat sources, as temperature and humidity fluctuations can impact the medication's effectiveness. Disposal of any unused or expired tablets should be done responsibly; do not flush them or pour them down the drain. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Keep the medication away from children to prevent accidental consumption, and always ensure the container is securely closed after each use.

Following are the quick tips for Hydroxyzine Hcl 25mg Tablet:

• Consult a doctor or pharmacist for personalized advice before taking this medication.
• Take the tablet as directed by your healthcare professional.
• Ensure you understand the dosage instructions and duration of treatment.
• Avoid operating heavy machinery or driving until you know how the medication affects you.
• Inform your doctor about other medications to prevent potential interactions.
• Store the tablets at room temperature, away from moisture and light.
• Do not share this medication with others; individual medical advice is essential.