S-Gliptin (100mg) 14 Tablets

Sitagliptin is a medication that acts as a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is a type of enzyme found in the body that is responsible for breaking down hormones that help to regulate blood sugar levels. By inhibiting the action of DPP-4, sitagliptin helps to increase the levels of these helpful hormones, which in turn stimulates insulin production and lowers blood glucose levels. When taken orally, sitagliptin is absorbed into the bloodstream and actively works to inhibit the activity of DPP-4 enzymes. This inhibition is particularly important for two hormones, glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones, known as incretins, are responsible for stimulating insulin secretion and inhibiting glucagon secretion, both of which help to lower blood glucose levels. Normally, these incretins would be rapidly broken down after their release, but in the presence of sitagliptin, this breakdown is prevented, resulting in extended actions of these hormones.The increase in incretins due to the action of sitagliptin leads to stimulation of insulin secretion in a manner that depends on the current level of blood glucose. This means that insulin secretion is regulated accordingly, ensuring that blood glucose levels remain within a healthy range. Beyond its effects on glucose regulation, sitagliptin may also have other beneficial effects on body weight and cardiovascular risk factors due to the extended duration of action of incretins.

Dipeptidyl Peptidase-4 (Dpp-4) Inhibitors

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of type 2 diabetes mellitus
• Sitagliptin helps to lower blood sugar levels after meals
• Preventing serious complications of diabetes mellitus, such as kidney damage
• Reduce the risk of stroke
• Prevent serious heart problems
• May be used alone or in combination with other diabetes medications
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• The recommended dose for treatment of type 2 diabetes is 50mg once daily and can be increased to 100mg for select patients.
• For patients with renal impairment (eGFR between 30 and <50mL/min), the recommended dose is 50mg once daily.
• For adults, the recommended dose for treatment of diabetes after solid organ transplantation is 100mg once daily.
• When switching from another dipeptidyl peptidase-4 (DPP-4) inhibitor, continue at the same total daily dose.
• Sitagliptin should be taken with food to maximize systemic exposure.

Overdosing on Sitagliptin, especially at a dose of 100mg, should be considered a medical emergency in order to avoid potential harm to the patient. Sitagliptin is a medication prescribed to treat type 2 diabetes, and is typically prescribed in smaller doses, such as 50 or 100mg once daily. If a patient has taken an excessive dose of Sitagliptin, it is crucial to contact local emergency services or visit the nearest emergency room for appropriate medical care. In the case of an overdose, patients may experience a variety of symptoms including hypoglycemia (low blood sugar), nausea, vomiting, dizziness, diarrhea, and abdominal pain. Seeking emergency medical care can help prevent more severe symptoms and complications like hypoglycemic coma or pancreatitis.

It is crucial to adhere to the prescribed medication schedule for Sitagliptin, but there are actionable steps to take if you miss a dose. If you remember a missed dose within an hour or so of your usual dosing time, you should take it immediately, ensuring there is minimal delay between the usual timing and when you take the missed dose. Generally, it is not necessary to take an extra dose, and you can continue with your regular dosing schedule. However, if it has been longer than an hour since your usual dose timing, it is advised to disregard the missed dose and follow your typical dosing schedule. Taking multiple doses close together can unnecessarily raise the risk of side effects and will not provide additional benefits. To maintain stable treatment levels in your blood, merely taking the next dose at the regular time will be helpful. If you have any doubts or concerns, it is advisable to consult your physician or pharmacist to guide you on the best way forward.

Before you begin using Sitagliptin, it's important to read the dosage instructions provided by the manufacturer or your doctor. These instructions may vary from other medications, so it's important to follow the specific directions for this medication. To take the tablet, simply swallow it whole with a glass of water. Do not crush or chew the tablet. If you have difficulty swallowing, it's essential to inform your doctor, as there may be liquid or oral suspension alternatives available.It is typical to take Sitagliptin once per day, at the same time each day. You should take it consistently, with or without food, but it's important to be consistent with food or without food, to avoid an upset stomach. If you forget to take your dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not double up to catch up on the missed dose.It is important to only take Sitagliptin as prescribed by your doctor and only for the condition being treated. Keep the medication in a safe place, out of the reach of children and pets. If you have any questions or concerns about using Sitagliptin, it is always best to consult with a healthcare professional, pharmacist, or your doctor. They can provide more personalized and up-to-date directions to ensure you use the medication safely and effectively.

Discerning instances where this medication may not be appropriate:

• Sitagliptin is a drug used to treat type 2 diabetes, but it may not be suitable in the following situations

• Hypoglycemia or low blood sugar
• Kidney impairment or chronic kidney disease
• Pancreatitis or history of inflamed pancreas
• Gastrointestinal issues such as nausea or vomiting
• Allergic reaction specifically to Sitagliptin or the medication's other ingredients
• Acute angle closure glaucoma.

Unraveling the side effects lurking behind this medications are as follows:

• Hypoglycemia (low blood sugar)
• Body weight loss
• Thirst or increased urination
• Sore throat
• Headaches
• Bacterial or viral infections
• Rash
• Swelling in the legs
• Muscle pain
• Nausea
• Diarrhea
• Vomiting
• Loss of appetite
• Dizziness
• Hyperglycemia (high blood sugar)

Sitagliptin is a medication prescribed to adults and children with type 2 diabetes to help lower their blood sugar levels. It works by blocking the breakdown of glucagon-like peptide 1 (GLP-1), a peptide hormone that helps stimulate the release of insulin and suppresses glucagon, both of which help to manage blood sugar levels. Sitagliptin is typically administered as a tablet to be taken orally, with or without food, and it's usually taken once daily. The specific dosage and regimen depend on the individual's medical condition, glucose levels, and response to the medication, so it's important to follow the instructions provided by a physician or healthcare provider. To ensure the efficacy and safety of Sitagliptin, it should be stored in a cool, dry place, away from heat and direct light. It should be kept out of reach of children and pets, and discarded if it has expired. It is not usually advised to freeze Sitagliptin tablets, and for disposal, it's recommended to consult with a physician or local healthcare center for guidance. In summary, Sitagliptin is a medication used to help manage blood sugar levels in those with type 2 diabetes. It works by affecting hormone levels that regulate insulin and blood sugar, is typically taken once daily, and should be stored safely and disposed of properly to ensure its efficacy and safety.