Safepram (5mg) 14 Tablets

Safepram (5mg) 14 Tablets

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  • Manufacturer MARTIN DOW PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Escitalopram

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Escitalopram is an antidepressant that belongs to the selective serotonin reuptake inhibitor (SSRI) class of drugs. It is composed of the S-enantiomer of citalopram, which provides it with unique properties. Serotonin is a neurotransmitter that helps regulate emotional balance, mood stability, appetite, sleep cycles, and social behavior. Escitalopram helps alleviate symptoms of depression and anxiety by inhibiting the reuptake of serotonin in the brain. This mechanism of action increases serotonin levels in the neural synaptic gaps, enhancing its presence in the brain's nerve junctions. By boosting mood and promoting a sense of calmness, Escitalopram helps restore serotonin levels, providing relief from symptoms such as sadness, irritability, and a lack of interest in enjoyable activities. The increased serotonin levels triggered by Escitalopram can help alleviate depressive moods, anxieties, and a negative cognitive frame of mind. Escitalopram takes time to manifest its full effects since it aims to achieve a balanced serotonin level.

  • Ingredients

    Escitalopram
  • Drug Class

    Selective Serotonin Reuptake Inhibitors (Ssris)

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treat anxiety in adults and adolescents
    • Treat depression in adults and adolescents who are aged 13 years and older
    • May be used for relief of symptoms of panic disorder with or without agoraphobia in adults
    • Used to treat dentitional distress in adults and adolescents who are aged 17 years and older
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Depression - Escitalopram is usually started at a dose of 10 mg per day. Depending on how you respond to the medication, your doctor may increase the dose to 20 mg per day.
    • Anxiety - The usual dose of Escitalopram is 10 mg per day. In some cases, your doctor may increase it to 20 mg daily depending on the severity of your condition and your response to the medication.
    • Panic disorder - Initially, Escitalopram is often prescribed at a dose of 10 mg daily. If this dose is not effective, your doctor may increase it to 20 mg per day.
  • In case of Overdose

    Escitalopram is a medication predominantly used to treat anxiety and depression and should be prescribed by a physician. It is essential to follow the prescription instructions very carefully as the dose varies on the response to the medication. Overdosing on Escitalopram may result in the following symptoms:

  • Missed Dose

    Maintaining a regular medication schedule for Escitalopram is vital, as it ensures the treatment stays effective. If you miss a dose, take it as soon as possible, but if it's almost time for the next dose, skip the missed one and continue with the regular schedule. Doubling up on Escitalopram should only be done under a doctor's guidance. In case of a missed dose, always consult a healthcare professional for safe and effective medication advice specific to your case.

  • How To Use

    Before starting Escitalopram, be sure to read the medication guide provided by your pharmacist. It is important to understand the potential side effects of the medication. If you have any concerns, speak to your doctor or pharmacist. Escitalopram is intended for once-daily use, preferably in the morning. This helps manage anxiety and depression throughout the day. Remember to take it at the same time every day to develop a routine. Instead of crushing, breaking, or chewing the tablet, swallow it whole with water. If swallowing is an issue, you may use food to help, provided it doesn't interfere with the tablet's effectiveness. If you experience stomach irritation, taking it with food may help. If you miss a dose, take it as soon as you can. If your next dose is approaching, skip the missed dose and stay on your regular schedule. Do not take more to catch up. Store Escitalopram at room temperature in a cool, dry place, away from direct sunlight and heat. When taking this medication, be careful when driving or operating machinery. Escitalopram may cause dizziness or drowsiness. Inform your doctor if you experience any changes in mood or behavior, including suicidal thoughts. Suicidal thoughts may be a symptom of illness or a side effect of the medication. Always follow the instructions from your doctor. If you have questions or concerns about your treatment plan, speak to your doctor or pharmacist.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Are allergic to Escitalopram or any of its active or inactive ingredients. If you are unsure if you are allergic, consult a doctor before taking this medication.
    • Have experienced manic episodes due to bipolar disorder, or if you have agitated depression.
    • Have kidney disease
    • Have liver disease
    • Have heart disease or have had previous heart attacks
    • Have problems with your esophagus (tube leading to the stomach) or intestines
    • Have asthma
    • Have a gluten allergy
    • Are pregnant or plan to become pregnant
    • Are breastfeeding
    • Have a history of seizures
    • Have thoughts of suicide or are struggling with depression
    • Are taking any medications, including supplements, and herbal products
    • Have problems with dizziness or coordination
    • Drink alcohol
    • Are sensitive to sunlight
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Mild digestive problems such as upset stomach, nausea, vomiting, and constipation
    • Increased thirst and urination, resulting in frequent visits to the bathroom
    • Changes in appetite, weight loss, or weight gain
    • Dizziness, unsteadiness, and an increased risk of falling
    • Feeling tired or having difficulties sleeping
    • Emotional symptoms like crying spells, irritability, agitation, and suicidal thoughts or behaviors
    • Consult your doctor if you experience any of these symptoms persistently
  • Precautions & Warnings

    The warnings and precautions associated with Escitalopram are:

    • Patient with history of seizure disorder or condition predisposing to seizures (e.g. brain damage, alcoholism), controlled epilepsy.
    • History of mania/hypomania or suicide-related events, significant degree of suicidal ideation.
    • Diabetes, known bleeding tendencies, bradycardia, recent acute MI, uncompensated heart failure, electrolyte disturbances (e.g. hypokalaemia, hypomagnesaemia), angle-closure glaucoma or history of glaucoma, metabolic disease.
    • Avoid abrupt withdrawal.
    • Avoid use in patients with unstable epilepsy.
    • Concomitant electroconvulsive therapy.
    • CYP2C19 ultrarapid, intermediate, or poor metabolisers.
    • Hepatic and severe renal (CrCl <30 mL/min) impairment.
    • Children and elderly.
  • Drug Interactions

    The drug interactions with escitalopram include:

    • MAO Inhibitors – Concurrent use with monoamine oxidase inhibitors (MAOIs) can lead to serotonin syndrome, a potentially life-threatening condition.
    • Other Antidepressants – Combining with other antidepressants, especially SSRIs or SNRIs, can increase the risk of serotonin syndrome.
    • Anticoagulants and Antiplatelet Agents – Escitalopram can increase the risk of bleeding when used with anticoagulants or antiplatelet drugs such as warfarin or aspirin.
    • NSAIDs – Non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding when used with escitalopram.
    • CYP3A4 Inhibitors – Escitalopram metabolism can be affected by CYP3A4 inhibitors like ketoconazole, leading to increased escitalopram levels and potential side effects.
    • CYP2C19 Inhibitors – Inhibitors of CYP2C19, such as omeprazole, can increase escitalopram levels, potentially leading to an increased risk of side effects.
    • Lithium – Combining escitalopram with lithium may increase the risk of serotonin syndrome and require careful monitoring.
    • Alcohol – Escitalopram can enhance the sedative effects of alcohol, leading to increased drowsiness and impaired coordination.
    • St. John's Wort – This herbal supplement can interact with escitalopram, potentially leading to serotonin syndrome and reducing the effectiveness of escitalopram.
    • Tramadol – The combination with tramadol can increase the risk of serotonin syndrome and requires careful monitoring.
  • Food Interactions

    The food interactions that should be considered before using Escitalopram are:

    • Alcohol can increase the nervous system side effects of the product such as dizziness drowsiness and difficulty concentrating.
    • Avoid or limit the use of alcohol while being treated with the product.
  • Storage/Disposal

    Escitalopram is a type of antidepressant medication that is categorized as a serotonin-selective serotonin and norepinephrine reuptake inhibitor (SSNI). This medication is prescribed to patients to treat depression and anxiety. It is important to consult a doctor before taking Escitalopram to ensure that the user is suited for the medication and to administer the correct dosage according to their medical needs. The medication should be stored at room temperature to ensure maximum effectiveness. It is also crucial to keep this medication away from children or pets' reach. If a dose is missed, take it as soon as possible. However, if it is almost time for the next scheduled dose, skip the missed dose and proceed with the regular schedule. An overdose of Escitalopram could be harmful, so it is vital to adhere to the prescription given by the doctor. If any side effects occur, it is essential to contact a healthcare specialist immediately.

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