SAINCAL D CAP

Calcium, Cholecalciferol (Vitamin D3) capsules have a synergistic mechanism of action. Calcium is an essential mineral that plays a crucial role in maintaining bone health and various physiological processes. When administered orally, calcium is absorbed in the small intestine, primarily in the duodenum and jejunum. It is then transported through the bloodstream to various tissues, including bones. Cholecalciferol, or Vitamin D3, is a fat-soluble vitamin that acts as a prohormone. When exposed to sunlight, it is converted in the skin into its active form, calcitriol. Calcitriol enhances calcium absorption in the intestine by increasing the expression of calcium transport proteins, allowing for more efficient uptake of calcium from the diet. Additionally, Vitamin D3 promotes the mineralization of bones by regulating calcium and phosphate homeostasis, ensuring proper bone formation and maintenance. This combined action of calcium and cholecalciferol helps prevent or treat calcium and vitamin D deficiencies, supporting overall bone health and reducing the risk of osteoporosis.

Calcium, Cholecalciferol

Vitamin D3 and Calcium supplement.

Capsule

The following are the uses of Calcium, Cholecalciferol Capsule:

• Used for treating and preventing low levels of calcium and vitamin D, essential for bone health.
• Used to strengthen bones and improve bone density.
• Used for managing conditions like osteoporosis and osteomalacia.
• Used to support proper muscle function and nerve signaling.
• Used to enhance calcium absorption in the body, promoting overall health.
• Used for maintaining immune system function and reducing inflammation.
• Used to prevent and manage rickets, a bone deformity disorder in children.
• Used to support overall well-being and prevent vitamin D deficiency.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Calcium- 1,000-1,200 mg per day for preventing and treating osteoporosis and osteopenia in adults.
• Vitamin D- Recommended dietary allowance (RDA) is 600-800 IU per day for most adults, some experts suggest higher doses ranging from 1,000-4,000 IU per day for maintaining optimal calcium absorption and bone health in adults.
• Vitamin D requirements vary across individuals, and factors like age, skin color, location, and lifestyle can influence the need for supplementation.
• Consulting a healthcare provider is vital for personalized guidance on vitamin D intake, especially for specific medical conditions or medications that affect vitamin D levels.

In the case of an overdose of Calcium and Cholecalciferol Capsules, the individual may experience symptoms such as nausea, vomiting, constipation, and increased thirst. More severe cases can lead to confusion, irregular heartbeat, and even coma. Promptly seek medical assistance and inform healthcare professionals about the overdose. They will provide the necessary guidance and treatment to manage the symptoms and prevent potential complications. It is crucial to take immediate action and not delay seeking professional help.

In the case of a missed dose of Calcium and Cholecalciferol capsules, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent routine with this medication, but if you miss a dose occasionally, simply resume your regular schedule without taking extra capsules.

To take the Calcium, Cholecalciferol Capsule, swallow the capsule whole with a glass of water, preferably with a meal or as directed by your healthcare professional, ensuring you follow the prescribed dosage and schedule provided for your specific needs.

Following are the conditions/situations when Calcium, Cholecalciferol Capsule should not be used:

• Should not be taken by individuals with a known allergy to Calcium, Cholecalciferol or any of its excipients.
• Contraindicated in patients with high levels of calcium in their blood (hypercalcemia) or those with conditions that cause excessive calcium accumulation.
• Not suitable for individuals with impaired kidney function or kidney stones.
• Should be avoided in patients with sarcoidosis, as it can affect calcium metabolism.
• Not recommended for individuals with vitamin D toxicity or those with conditions that cause excessive vitamin D levels.
• Should not be used in patients with hypervitaminosis D, a condition of excessive vitamin D intake.
• Contraindicated in individuals with a history of allergic reactions to vitamin D supplements.
• Should be used with caution and under medical supervision in patients with cardiovascular diseases or conditions that affect heart function.

The side effects of Calcium, Cholecalciferol Capsule may include:

• Constipation
• Nausea and vomiting
• Dry mouth
• Increased thirst
• Frequent urination
• Fatigue and muscle weakness
• Bone and joint pain
• Allergic reactions (such as rash, itching, or swelling)

Following are the precautions and warnings for Calcium, Cholecalciferol Capsule:

• This medication should not be taken if you have a known allergy to calcium, cholecalciferol, or any of the excipients in the capsule.
• Patients with a history of kidney stones or kidney disease should use this medication with caution, as it may increase the risk of stone formation.
• Regular monitoring of calcium levels is advised, especially in long-term use, to prevent hypercalcemia (high calcium levels in the blood).
• Individuals with a history of hypercalciuria (high calcium levels in urine) should be monitored, as this medication can exacerbate the condition.
• Patients with impaired liver function should exercise caution as cholecalciferol (Vitamin D) is metabolized in the liver.
• Elderly individuals may be more susceptible to the effects of this medication, especially on the kidneys, and should be monitored closely.
• Always take this medication as directed by your healthcare provider. Do not exceed the recommended dosage.

Following are the drug interactions for Calcium, Cholecalciferol Capsule:

• Thiazide diuretics may decrease the excretion of calcium, leading to higher calcium levels in the body.
• Antacids containing aluminum or magnesium can reduce the absorption of calcium and cholecalciferol.
• Calcium can decrease the absorption of tetracycline antibiotics, so it is best to separate doses by a few hours.
• Phenytoin, phenobarbital, and rifampin may decrease vitamin D levels, reducing the effectiveness of cholecalciferol.
• Steroids like prednisone can increase calcium excretion, requiring careful monitoring of calcium levels.
• Bisphosphonates used for osteoporosis may have reduced absorption when taken with calcium supplements.
• Calcium can potentially interact with cardiac medications like digoxin, requiring close monitoring of digoxin levels.

Following are the food interactions for Calcium, Cholecalciferol Capsule:

• Consuming foods rich in calcium like dairy products, leafy greens, and fortified foods can enhance the absorption of calcium from the supplement, ensuring better bone health.
• Vitamin D-rich foods such as fatty fish, egg yolks, and liver can complement the Cholecalciferol (Vitamin D3) in the capsule, promoting better calcium absorption.
• Oxalate-rich foods like spinach, rhubarb, and certain nuts and seeds can bind with calcium, reducing its absorption. It's best to consume calcium supplements at a different time from these foods.
• Phytic acid in whole grains, legumes, and nuts can also inhibit calcium absorption. Soaking, sprouting, or fermenting these foods can reduce phytic acid content.
• Sodium and caffeine can increase calcium excretion in urine, so limiting high-sodium and caffeinated foods and beverages is advisable.
• A balanced diet rich in fruits, vegetables, and lean proteins can support the overall effectiveness of the supplement by providing essential nutrients for bone health.
• Ensure an adequate intake of Vitamin K, found in leafy greens, as it plays a role in bone metabolism alongside Calcium and Vitamin D.
• Always take the supplement with a meal to improve absorption and reduce the risk of gastrointestinal side effects.

Calcium, Cholecalciferol Capsule storage requires a cool, dry environment, away from sunlight and moisture. Store it in its original container, tightly sealed, to maintain its integrity. Avoid bathroom storage or placing it near heat sources like stoves, as temperature fluctuations can impact its effectiveness. Dispose of any unused capsules carefully; do not flush or pour them down the drain. Consult a pharmacist for proper disposal methods, and keep the medication out of children's reach to prevent accidental consumption. Always check the expiration date, and discard expired capsules appropriately, ensuring safe and responsible handling.

Following are the quick tips for Calcium, Cholecalciferol Capsule:

• Consult your doctor before use, especially if you have kidney stones or kidney disease.
• Take the capsule with a full glass of water to aid in absorption.
• Avoid taking the capsule with high-fibre foods as it may interfere with absorption.
• Consider taking the capsule with meals to reduce the risk of stomach upset.
• Maintain a consistent schedule for taking the capsule as directed by your healthcare provider.
• Do not crush or chew the capsule; swallow it whole for optimal effectiveness.
• Ensure you stay well-hydrated while taking this medication.

It is important to monitor your lab values while taking Calcium and Vitamin D3 to ensure you are within the optimal range and avoid any potential risks. Depending on a person's age, health condition, and other factors, the tests required may vary. However, it is recommended to perform the following standard lab tests: