SALNON 100/50MG INH

Albuterol is a short-acting beta-2 agonist that relaxes the smooth muscles in the airways. It achieves this by binding to beta-2 adrenergic receptors in the bronchial smooth muscle, leading to the activation of adenylate cyclase and subsequent increase in intracellular cyclic AMP (cAMP). This rise in cAMP relaxes the bronchial smooth muscles, resulting in bronchodilation and improved airflow. On the other hand, Beclomethasone, a corticosteroid, exhibits its anti-inflammatory effects by inhibiting the release of inflammatory mediators and suppressing the immune response. It binds to intracellular glucocorticoid receptors, which, upon activation, are translocated to the nucleus, where they regulate the expression of various genes involved in inflammation. This leads to a decrease in the production of pro-inflammatory cytokines and chemokines, reducing inflammation in the airways.

Albuterol, Beclomethasone 50mcg

Bronchodilator and corticosteroid

Spray

The following are the uses of Albuterol, Beclomethasone 50mcg Spary:

• Used for preventing and managing asthma symptoms, such as wheezing and shortness of breath.
• Used for reducing inflammation in the airways to improve breathing.
• Used for controlling exercise-induced asthma.
• Used for treating chronic obstructive pulmonary disease (COPD) symptoms.
• Used for providing quick relief during asthma attacks or sudden breathing difficulties.
• Used for decreasing mucus production in the airways.
• Used for maintaining lung function and preventing asthma exacerbations.

In the case of an overdose of Albuterol and Beclomethasone 50mcg Spray, individuals may experience symptoms such as rapid heart rate, tremors, nervousness, and increased blood pressure. These symptoms can be more severe in children. It is important to contact a healthcare professional or poison control center immediately for guidance on managing the overdose. Prompt medical advice should be sought to address any potential health risks associated with excessive use.

In the case of a missed dose of Albuterol, it is recommended to take the medication as soon as you remember, but if it is almost time for the next scheduled dose, skip the missed dose and continue with your regular schedule. For Beclomethasone 50mcg Spray, if a dose is missed, administer it as soon as possible, but if it's close to the next dose, skip the missed dose and continue with the regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects.

To use Albuterol and Beclomethasone 50mcg Spray, prime the inhaler by shaking well, then exhale gently, place the mouthpiece in your mouth, inhale deeply while pressing down on the canister, hold your breath for a few seconds, and repeat as directed by your healthcare provider.

Following are the conditions/situations when Albuterol and Beclomethasone 50mcg Spray should not be used:

• Should not be used in individuals with a known allergy to Albuterol, Beclomethasone, or any of the excipients in the formulation.
• Not suitable for patients with a history of severe allergic reactions to other medications or substances.
• Contraindicated in patients with a history of paradoxical bronchospasm with similar medications.
• Should not be used in patients with untreated or unstable cardiovascular conditions, including severe heart disease or hypertension.
• Not recommended for individuals with glaucoma or cataracts.
• Should be avoided in patients with active or untreated infections, especially tuberculosis.
• Not suitable for individuals with a history of hypersensitivity to other corticosteroids.
• Should not be used in patients with untreated fungal, bacterial, or viral infections in the respiratory tract.
• Contraindicated during severe acute asthma attacks where intensive measures are required.

The side effects of Albuterol and Beclomethasone 50mcg Spray may include:

• Tremor or shaking
• Headache
• Throat irritation or dryness
• Cough or hoarseness
• Nausea or dizziness
• Palpitations or increased heart rate
• Muscle cramps or joint pain
• Skin bruising or thinning (with long-term use)

Following are the precautions and warnings for Albuterol, Beclomethasone 50mcg Spray:

• Avoid use in patients with known hypersensitivity to albuterol, beclomethasone, or any other components of the spray.
• Use with caution in patients with cardiovascular diseases, as albuterol may cause increased heart rate, palpitations, or hypertension.
• Long-term use of corticosteroids like beclomethasone may lead to oral thrush; patients should rinse their mouth after each use.
• Overuse of albuterol may result in paradoxical bronchospasm or decreased effectiveness.
• Not recommended for acute asthma attacks; a fast-acting bronchodilator should be used in emergencies.
• Patients with diabetes should use with caution, as albuterol may increase blood glucose levels.
• Monitor patients with osteoporosis, as prolonged corticosteroid use may weaken bones.
• Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use.
• Store the inhaler in a cool, dry place and avoid exposure to direct heat or open flames.
• If symptoms worsen or do not improve, seek medical attention immediately.

Following are the drug interactions for Albuterol and Beclomethasone 50mcg Spray:

• Albuterol may interact with other beta-adrenergic agonists, increasing the risk of cardiovascular side effects.
• Concomitant use of Beclomethasone with other potent CYP3A4 inhibitors can lead to increased systemic corticosteroid effects.
• Beclomethasone may decrease the effectiveness of medications used for treating fungal infections, such as ketoconazole.
• Antibiotics like clarithromycin can increase the systemic exposure of Beclomethasone.
• Albuterol may interact with certain antidepressants, such as MAOIs, causing potential cardiovascular issues.
• Caution is advised when using Albuterol with diuretics, as it may reduce the effectiveness of these medications.
• Beclomethasone can potentially interact with antidiabetic medications, affecting blood glucose control.

Following are the food interactions for Albuterol and Beclomethasone 50mcg Spray:

• Avoid consuming large amounts of caffeine-containing foods and beverages (e.g., coffee, tea, energy drinks, chocolate) as Albuterol may increase the effects of caffeine, leading to potential side effects like increased heart rate and nervousness.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Albuterol, potentially altering its effectiveness.
• Beclomethasone may cause an increase in blood sugar levels. Monitor your blood sugar levels closely, especially if you have diabetes, and adjust your diet as advised by your doctor.
• Limit the intake of high-sodium foods as Beclomethasone can cause sodium retention, which may lead to increased blood pressure.
• Avoid excessive alcohol consumption as it can increase the risk of gastrointestinal side effects and may also interfere with the effectiveness of Beclomethasone.
• Maintain a well-balanced diet to support overall health and manage potential side effects such as weight gain or bone density loss associated with long-term corticosteroid use.
• Consult your healthcare provider for personalized dietary recommendations, especially if you have specific dietary restrictions or medical conditions.
• Ensure you follow the prescribed dosage and administration instructions for both medications to minimize potential food-related interactions and optimize their therapeutic effects.

Albuterol and Beclomethasone 50mcg Spray should be stored in a controlled environment, preferably at room temperature, between 68°F and 77°F (20°C and 25°C). Keep the medication away from excessive heat, direct sunlight, and moisture, as these conditions can degrade the medication's quality. Ensure the spray bottle is tightly sealed after each use to maintain its integrity. When disposing of the medication, do not throw it into the trash or flush it down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for advice on safe disposal methods. It is crucial to keep the medication securely stored and out of the reach of children and pets to prevent accidental exposure.

Following are the quick tips for Albuterol and Beclomethasone 50mcg Spray:

• Consult your doctor before use, especially if you have heart disease, high blood pressure, or diabetes.
• Follow the prescribed dosage and inhalation technique for optimal effectiveness.
• Shake the inhaler well before each use to ensure proper medication delivery.
• Ensure you breathe out fully before inhaling the medication.
• Clean your inhaler regularly as per the manufacturer's instructions.
• Store the inhaler at room temperature, away from direct sunlight and heat.
• Do not puncture or burn the aerosol container, even when empty.
• Keep track of your medication usage to know when to refill or reorder.