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Cyclosporin
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Product Information
Cyclosporin is a potent immunosuppressive agent that primarily acts by inhibiting T-lymphocyte activation. It selectively binds to cyclophilin, a cytosolic protein in T-lymphocytes, forming a cyclosporin-cyclophilin complex. This complex then blocks the calcium-dependent signaling pathway in T-cells by inhibiting the enzyme calcineurin. Calcineurin is responsible for activating a transcription factor known as NF-AT (nuclear factor of activated T-cells), which is essential for the expression of genes required for T-cell activation, such as interleukin-2 (IL-2). By inhibiting calcineurin, cyclosporin prevents the translocation of NF-AT into the nucleus, thereby suppressing the production of IL-2 and other cytokines, and ultimately inhibiting T-cell-mediated immune responses.
Cyclosporin
Immunosuppressant
Injection
The following are the uses of Cyclosporin injection:
In the case of an overdose of Cyclosporin injection, prompt medical intervention is necessary. Symptoms may include kidney damage, high blood pressure, and tremors. It is important to seek medical help immediately, as the healthcare provider will determine the most appropriate treatment, which may include monitoring kidney function, controlling blood pressure, and providing supportive care to manage symptoms and prevent further complications. The treatment approach will depend on the severity of the overdose.
In the case of a missed dose of Cyclosporine injection, it is important to take the following steps If you remember within a few hours of the missed dose, administer the injection as soon as possible. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you have any concerns or questions regarding missed doses. They can provide guidance on how to manage missed doses and ensure the effectiveness of your treatment.
To administer the Cyclosporin injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, inject the prescribed dose slowly, and then withdraw the needle, applying pressure with a sterile gauze pad if needed to prevent bleeding.
Here are the conditions or situations when Cyclosporin injection should not be used:
The side effects of Cyclosporin injection may include:
Following are the precautions and warnings for Cyclosporin injection:
Following are the drug interactions for Cyclosporin injection:
Following are the food interactions for Cyclosporin injection:
Cyclosporin injection should be stored in a controlled environment, preferably between 2°C and 8°C (36°F and 46°F) in a refrigerator. Protect the medication from light and do not freeze it, as this can damage the solution. Always check the expiration date on the vial before use and discard any expired or unused vials according to local regulations. Do not dispose of this medication by flushing it down the toilet or pouring it into a drain; instead, contact your healthcare provider or pharmacist for guidance on safe disposal practices. Keep Cyclosporin injection out of the sight and reach of children and pets to prevent accidental exposure or ingestion.
Following are the quick tips for Cyclosporin injection:
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