Scabfree (5%) 60ml Lotion

Permethrin lotion is a topical medication primarily used to treat scabies, and its mechanism of action revolves around its potent insecticidal properties. It acts by targeting the nervous system of the scabies mite (Sarcoptes scabiei). Permethrin is a synthetic pyrethroid that binds to the voltage-gated sodium channels in the mite's nerve cells, causing a rapid influx of sodium ions. This leads to prolonged nerve membrane depolarization, resulting in paralysis and eventual death of the scabies mite. The selective toxicity of permethrin towards the mite is attributed to the higher sensitivity of the mite's nervous system to the effects of permethrin compared to the mammalian nervous system. This mechanism makes permethrin an effective treatment for scabies infestations.

Insecticide lotion

Lotion

The following are the uses of Permethrin Lotion:

• Used for treating head lice infestations, effectively killing the lice and their eggs.
• Used for preventing and controlling scabies, a skin condition caused by mites.
• Used for treating pubic lice, providing relief from itching and eliminating the infestation.
• Used for managing and preventing body lice, ensuring thorough treatment.
• Used for general skin protection against various parasitic insects.
• Used for reducing the risk of contracting certain insect-borne diseases.
• Used for providing peace of mind during outdoor activities in infested areas.

To be used as per doctor's prescription

In the case of an overdose of Permethrin Lotion, it is important to remain calm and take appropriate actions. Remove any contaminated clothing and wash the affected skin thoroughly with soap and water. Discontinue further use of the lotion and contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the severity of the overdose and may recommend further treatment or observation.

In the case of a missed dose of Permethrin Lotion, it is important to apply the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one. However, do not apply extra lotion to make up for the missed application. If you have missed multiple doses, contact your healthcare provider for guidance, as they may recommend a specific course of action to ensure the treatment remains effective. It is generally advised to resume the treatment and maintain a consistent schedule moving forward.

To use Permethrin Lotion, apply the lotion to dry skin, ensuring full coverage from head to toe, and leave it on for 8-14 hours or as directed by your healthcare provider, then rinse thoroughly with warm water.

Following are the conditions/situations when Permethrin Lotion should not be used:

• Avoid using if you have a known allergy or sensitivity to permethrin or any of the lotion's components.
• Do not use if you have open wounds or broken skin in the affected area.
• Not recommended for infants, especially those younger than 2 months old, without medical advice.
• Avoid contact with eyes, nose, mouth, and other sensitive areas.
• Do not use on the scalp or face unless directed by a healthcare professional.
• Should not be used if you have a history of seizures or are taking medications that lower the seizure threshold.
• Not suitable for individuals with severe skin conditions like eczema or psoriasis without medical supervision.
• Do not use if you are pregnant or breastfeeding without consulting a healthcare provider.
• Avoid using on inflamed, irritated, or infected skin.

The side effects of Permethrin Lotion may include:

• Skin irritation or redness at the application site
• Mild burning or stinging sensation
• Itching or rash
• Dry skin
• Numbness or tingling
• Swelling or inflammation
• Allergic reactions (hives, difficulty breathing, swelling of the face/lips/tongue)
• Eye irritation (if the lotion gets into the eyes)

Here are the precautions and warnings for Permethrin Lotion:

• Do not use on open wounds, cuts, or irritated skin.
• Avoid contact with eyes, nose, mouth, and other sensitive areas. In case of contact, rinse thoroughly with water.
• This lotion is for external use only and should not be ingested.
• Wash your hands thoroughly after applying the lotion to avoid accidental ingestion.
• Do not use under occlusive dressings or bandages as it may increase the risk of skin irritation.
• Individuals with a history of skin sensitivity or allergies should perform a patch test before widespread application.
• Keep out of reach of children and pets to prevent accidental ingestion or misuse.

Following are the drug interactions for Permethrin Lotion:

• Permethrin may interact with other topical medications containing alcohol or astringents, potentially causing skin irritation.
• Topical corticosteroids should be used cautiously with Permethrin, as they can reduce the effectiveness of the treatment.
• Antihistamines, when taken orally, might mask the early symptoms of allergic reactions to Permethrin.
• The use of other pediculicides (lice-killing agents) in combination with Permethrin may increase the risk of skin reactions.
• Some insect repellents containing DEET (N,N-Diethyl-m-toluamide) might reduce the efficacy of Permethrin when applied simultaneously.
• Certain sunscreens with high SPF values may decrease the penetration of Permethrin into the skin, potentially reducing its effectiveness.
• Ivermectin, an oral medication, can be used in combination with Permethrin for more severe cases, but close monitoring for adverse effects is necessary.
• Caution is advised when using Permethrin with other medications that have similar chemical structures, as this may increase the risk of side effects.

Following are the food interactions for Permethrin Lotion:

• Consuming alcohol is generally safe with Permethrin Lotion, but excessive alcohol intake should be avoided as it may increase the risk of skin irritation or sensitivity.
• Grapefruit and its juice should be consumed with caution as they can potentially inhibit certain enzymes, leading to increased drug levels in the body.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks may enhance the absorption of Permethrin, so monitor your intake.
• Foods high in fat can slow down the absorption of Permethrin, so consider applying the lotion before or after a high-fat meal.
• Avoid oily or greasy foods as they can affect the effectiveness of the lotion by reducing its absorption into the skin.
• Spicy foods might increase skin sensitivity, so it's advisable to moderate your intake to minimize any potential discomfort.
• Avoid excessive consumption of sugar, as it may interact with the medication's absorption and increase the risk of skin reactions.
• Stay well-hydrated by drinking plenty of water to support overall skin health during the treatment period.

Permethrin Lotion should be stored with care to ensure its effectiveness and safety. Keep the lotion in a cool, dry place, preferably at room temperature, away from sunlight and moisture. It is crucial to store it in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid extreme temperatures, such as those near stoves or radiators, as they can alter the lotion's properties. Always check the expiration date, and if the lotion is past its prime, do not dispose of it by flushing or pouring it down the drain. Instead, consult a pharmacist or healthcare provider for appropriate disposal methods to ensure environmental safety. Keep the lotion out of children's reach to prevent accidental exposure.

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Following are the quick tips for Permethrin Lotion:

• Apply the lotion to a clean, dry scalp and hair, ensuring full coverage.
• Leave the lotion on for the recommended duration, usually 8-12 hours.
• Rinse thoroughly with warm water after the treatment time.
• Avoid contact with eyes, nose, and mouth during application.
• Wash your hands thoroughly after applying the lotion.
• Do not use a hairdryer as it may reduce the effectiveness of the treatment.
• Repeat the treatment as directed by your healthcare professional if needed.