Scabi-Cap 75g Bar

Permethrin soap is a synthetic pyrethroid insecticide that acts by targeting the nervous system of insects. Its mechanism of action involves disrupting the normal function of sodium channels in nerve cells, leading to rapid depolarization and repetitive nerve impulses. Permethrin binds strongly to sodium channels in a partially open state, preventing them from returning to a resting state and causing prolonged activation of the nerve. This results in repetitive firing of the neurons, leading to paralysis and eventual death of the insect. The selectivity of permethrin for insect sodium channels, compared to mammalian sodium channels, contributes to its effectiveness as an insecticide while minimizing toxicity to humans.

Insecticide, Antiparasitic

soap

The following are the uses of Permethrin soap:

• Used for treating scabies infestations and relieving the associated itching.
• Used for head lice treatment, effectively killing both lice and their eggs.
• Used for preventing mosquito and tick bites in outdoor settings.
• Used for reducing the risk of malaria transmission by repelling mosquitoes.
• Used for treating and controlling bed bug infestations in homes.
• Used for managing pubic lice (crabs) infestations.
• Used for general skin hygiene and as an antiseptic cleanser.
• Used for soothing irritated skin and reducing inflammation.

In the case of an overdose of Permethrin soap, it is important to act swiftly. Symptoms may include skin irritation, redness, and itching. Rinse the affected area thoroughly with water and seek medical advice. Avoid using excessive amounts of the soap, and always follow the recommended dosage guidelines provided by the manufacturer. If ingested, contact a healthcare professional or poison control center for further instructions.

In the case of a missed dose of Permethrin soap, it is generally recommended to apply the soap as soon as you remember. However, if it's almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. It's important not to double the dose to make up for a missed one. If you frequently miss doses, consult your healthcare provider for advice on how to improve your treatment regimen and ensure maximum effectiveness.

To use Permethrin soap, wet your skin, apply the soap generously, work into a lather, leave on for 10 minutes, then rinse thoroughly, ensuring that you follow the prescribed duration of contact time for optimal effectiveness.

Following are the conditions/situations to avoid the use of Permethrin soap:

• Do not use if you are allergic to permethrin or any of the soap's ingredients.
• Avoid using if you have open wounds or severely damaged skin.
• Not recommended for children below 2 months old.
• Do not swallow or ingest; it is for external use only.
• Avoid contact with eyes, nose, and mouth.
• Avoid prolonged use without medical supervision.
• Discontinue use if you experience severe skin irritation or adverse reactions.
• Do not use if you are trying to treat scabies in animals; consult a veterinarian for appropriate treatment.

The side effects of Permethrin soap may include:

• Skin irritation or redness
• Itching or burning sensation at the application site
• Dry skin
• Mild rash or hives
• Stinging or tingling sensation
• Swelling or inflammation
• Allergic reactions (skin rash, breathing difficulties, swelling of the face/lips/tongue)
• Eye irritation (if the soap gets into the eyes)

Here are the precautions and warnings for Permethrin soap:

• For external use only. Avoid contact with eyes, nose, mouth, and other sensitive areas.
• Wash hands thoroughly after use to avoid accidental ingestion.
• Do not use on broken or irritated skin. Discontinue use if skin irritation or allergic reactions occur.
• Keep out of reach of children. Store in a secure place to prevent accidental ingestion.
• If you are using Permethrin soap for scabies, ensure all family members and close contacts are treated simultaneously to prevent re-infestation.
• Do not use if you are allergic to Permethrin or any of its components.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before using this product.

Following are the drug interactions for Permethrin soap:

• Permethrin may interact with other topical medications containing corticosteroids, as it can increase the risk of skin irritation and absorption of corticosteroids.
• The soap can reduce the effectiveness of insect repellent products containing DEET when applied simultaneously.
• Use with caution alongside 5-fluorouracil, as it may increase the risk of skin reactions.
• Avoid combining with other insecticides or scabicides to prevent potential toxic effects.
• Drug interactions with oral anticoagulants are possible, and monitoring of INR (International Normalized Ratio) is recommended.
• Permethrin can enhance the effects of warfarin, leading to increased bleeding risk.
• May increase the risk of seizures when used with seizure medications like carbamazepine.

Following are the food interactions for Permethrin soap:

• Permethrin can have increased skin absorption when applied after a hot shower or bath, so it is advisable to wait for some time before using the soap after bathing.
• Avoid consuming alcohol-based beverages while using this soap, as it may increase skin sensitivity and enhance the absorption of Permethrin.
• Grapefruit and grapefruit juice should be avoided as they can inhibit the CYP3A4 enzyme, potentially leading to increased levels of Permethrin in the body.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks might increase nervous system stimulation and should be consumed in moderation.
• Spicy foods might temporarily increase skin sensitivity, so it is best to limit their consumption while using Permethrin soap.
• Avoid oily and greasy foods as they can affect the overall effectiveness of the soap by hindering its ability to bind to the skin.
• It is generally recommended to maintain a balanced diet and stay well-hydrated to support overall skin health during the use of Permethrin soap.

Permethrin soap should be stored in a cool, dry area, specifically in a designated storage cabinet or shelf, ensuring it remains out of reach of children and pets. Maintain a consistent room temperature, avoiding exposure to direct sunlight, heat sources like radiators, or freezing conditions, as these can alter the soap's effectiveness. When disposing of Permethrin soap, it is crucial to avoid flushing it down the toilet or pouring it into drains. Instead, contact your local waste management facility or consult with a pharmacist for environmentally safe disposal options. This ensures the proper handling of the product, minimizing potential harm to the environment and public health. Always follow local regulations and guidelines for the safe disposal of medications.

Following are the quick tips for Permethrin soap:

• Wet your skin before applying the soap to create a lather.
• Massage the soap onto your skin gently for a thorough application.
• Leave the soap on your skin for the recommended time, usually 5-10 minutes.
• Rinse thoroughly with water after the prescribed time.
• Avoid contact with eyes and mucous membranes.
• Use as directed; do not exceed the recommended duration of treatment.
• Store the soap in a cool, dry place, away from direct sunlight.