SEDACRON 200MG TAB

Amiodarone 200MG Tablet primarily works by affecting the electrical activity in the heart. Its mechanism of action involves blocking certain ion channels in the heart cells, specifically potassium and calcium channels, which slows down the conduction of electrical impulses. This action helps to regulate the heart rate and maintain a regular heartbeat. Amiodarone also prolongs the duration of the cardiac action potential, which contributes to its anti-arrhythmic effect. By modulating these ion channels, Amiodarone can effectively suppress abnormal electrical activity and restore a normal heart rhythm in conditions such as ventricular and supraventricular arrhythmias.

Amiodarone 200MG

Antiarrhythmic

Tablet

The following are the uses of Amiodarone 200MG Tablet:

• Used for treating and preventing irregular heart rhythms, helping to restore a normal heartbeat.
• Used in cases of life-threatening rhythm disorders to quickly stabilize the heart.
• Effective in treating ventricular fibrillation and tachycardia, ensuring a steady heart rate.
• Can be used to maintain a regular heartbeat after other treatments have failed.
• Helps prevent sudden cardiac death by controlling abnormal heart rhythms.
• Suitable for managing various types of arrhythmias, offering a versatile treatment option.
• Provides long-term management for chronic arrhythmias, improving heart function.
• Used as an anti-arrhythmic medication, contributing to overall heart health.

In the case of an overdose of Amiodarone 200MG Tablets, individuals may experience a range of symptoms, including severe dizziness, fainting, and an irregular heartbeat. The severity of these symptoms can vary depending on the amount ingested. It is crucial to seek medical assistance promptly if an overdose is suspected, as healthcare professionals can provide the necessary treatment and support to manage any adverse effects and ensure the patient's well-being. Timely intervention is key to minimizing potential health risks.

In the case of a missed dose of Amiodarone 200MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or adjust the dosage accordingly to ensure its effectiveness.

To take Amiodarone 200MG Tablet, swallow the tablet whole with a full glass of water, usually once or twice daily, or as directed by your healthcare professional, and ensure you follow the prescribed dosage and treatment duration as instructed by your doctor.

Following are the conditions/situations when Amiodarone 200MG Tablet should not be used:

• Should not be used in individuals with a known allergy to Amiodarone or any of its components.
• Contraindicated in patients with a history of severe lung disease or severe respiratory distress.
• Not recommended for patients with a slow heart rate (bradycardia) or severe heart block (AV block).
• Should not be used in patients with a recent heart attack who are experiencing unstable vital signs.
• Contraindicated in individuals with a particular type of irregular heartbeat called 'torsades de pointes'.
• Not suitable for patients with low potassium or magnesium levels in the blood.
• Should not be used in patients with an artificial pacemaker, unless closely monitored.
• Contraindicated during pregnancy and breastfeeding.
• Should be used with extreme caution in patients with liver or kidney disease.
• Not recommended for individuals with a family history of a particular type of eye disease called 'corneal microdeposits'.

The side effects of Amiodarone 200MG Tablet may include:

• Skin sensitivity to sunlight (photosensitivity)
• Nausea and vomiting
• Loss of appetite
• Weight gain
• Fatigue and weakness
• Tremors or shaking
• Visual disturbances, including blurred or altered vision
• Breathing difficulties or coughing

Following are the precautions and warnings for Amiodarone 200MG Tablet:

• This medication can cause changes in heart rhythm, including a condition called QT prolongation. Regular monitoring of heart function is necessary during treatment.
• Patients with existing heart conditions, such as heart failure, slow heart rate, or recent heart attack, should use this medication with caution.
• Amiodarone can affect the lungs, causing respiratory issues. Any breathing difficulties should be reported to the doctor immediately.
• It may cause liver problems, so liver function tests are recommended during treatment.
• Patients with thyroid disorders should be monitored closely as Amiodarone can affect thyroid function.
• Avoid exposure to sunlight and use protective measures, as this medication can make your skin more sensitive to sunlight.
• Elderly patients may be more susceptible to side effects and should be closely monitored during treatment.

Following are the drug interactions for Amiodarone 200MG Tablet:

• It can interact with other antiarrhythmic drugs (e.g., sotalol, flecainide) and increase the risk of adverse cardiac effects.
• Amiodarone may enhance the effects of warfarin and other anticoagulants, requiring close monitoring of coagulation parameters.
• The use of Amiodarone with beta-blockers can lead to an excessive decrease in heart rate and blood pressure.
• It may reduce the metabolism of certain drugs, including cyclosporine and digoxin, leading to increased levels and potential toxicity.
• Caution is advised when combining Amiodarone with drugs metabolized by CYP3A4, as it may inhibit this enzyme, increasing drug concentrations.
• The risk of hypokalemia and arrhythmias may be elevated when Amiodarone is used with diuretics, especially loop diuretics.
• It may increase the plasma concentrations of statins, potentially increasing the risk of muscle-related side effects.

Following are the food interactions for Amiodarone 200MG Tablet:

• Grapefruit and grapefruit juice consumption should be limited as they can interfere with Amiodarone metabolism, potentially leading to increased drug levels in the blood.
• Alcohol intake should be minimized as it can enhance the sedative effects of Amiodarone, increasing the risk of dizziness and fainting.
• Avoid excessive caffeine intake, as Amiodarone may increase caffeine sensitivity, leading to rapid heartbeat and anxiety.
• High-salt foods should be reduced as Amiodarone can cause sodium retention, affecting blood pressure and heart health.
• Avoid high-fat meals as they may increase Amiodarone absorption, leading to higher blood concentrations and potential side effects.
• Limit licorice consumption as it can interact with Amiodarone, affecting potassium levels and heart rhythm.
• Be cautious with vitamin K-rich foods like leafy greens, as Amiodarone can impact blood clotting, requiring consistent vitamin K intake.

Amiodarone 200MG Tablets should be stored in a cool, dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, moisture, and heat sources like stoves or radiators. It is crucial to maintain the medication's integrity by storing it in its original packaging, tightly sealed, to prevent contamination. Always check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of it in household waste or pour it down the drain; instead, follow local guidelines or consult your pharmacist for safe disposal methods. Keep this medication securely stored, out of the reach of children, to prevent any accidental ingestion.

Following are the quick tips for Amiodarone 200MG Tablet:

• Take the tablet as directed by your doctor; do not adjust the dosage without medical advice.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Maintain a consistent medication schedule; take it at the same time each day.
• Regularly monitor your heart rate and blood pressure as advised by your doctor.
• Avoid sudden changes in posture to prevent dizziness and fainting.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the medication at room temperature, away from moisture and light.