Seef (25mg) 20 Tablets

Levosulpiride is a selective antagonist of dopamine D2 receptors, primarily found in the chemoreceptor trigger zone (CTZ) and the upper gastrointestinal tract. Its mechanism of action involves blocking these dopamine receptors, leading to a reduction in the inhibitory effect of dopamine on gastric motility and acid secretion. By doing so, levosulpiride enhances gastrointestinal motility, accelerates gastric emptying, and increases gastric accommodation, thereby improving digestive functions. This makes it effective in treating certain gastrointestinal disorders and relieving associated symptoms.

Levosulpiride 25mg

Antiemetic, antipsychotic, prokinetic.

Tablet

The following are the uses of Levosulpiride 25mg Tablet:

• Used for treating digestive system disorders like acid reflux, indigestion, and stomach ulcers.
• Used for managing symptoms of gastroesophageal reflux disease (GERD).
• Used to reduce nausea and vomiting.
• Used for stimulating appetite in cases of anorexia.
• Used for relieving abdominal pain and discomfort.
• Used to support the healing of the gastrointestinal lining.
• Used for promoting healthy digestion and reducing gastrointestinal inflammation.

In the case of an overdose of Levosulpiride 25mg Tablets, individuals may experience symptoms such as severe drowsiness, agitation, confusion, and extrapyramidal side effects. It is important to recognize that an overdose can lead to a medical emergency, especially if a large quantity is ingested. Promptly seek medical assistance and provide healthcare professionals with details regarding the amount consumed, as this information will aid in determining the appropriate treatment and ensuring the best possible outcome.

In the case of a missed dose of Levosulpiride 25mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for guidance on how to safely resume your medication regimen.

To take Levosulpiride 25mg Tablet, swallow the tablet whole with a glass of water, preferably before a meal, once or twice a day as directed by your doctor, ensuring you follow the prescribed dosage and duration for optimal results.

Following are the conditions when Levosulpiride 25mg Tablet should not be used:

• Should not be taken by individuals with a known allergy to Levosulpiride or other similar antipsychotic medications.
• Contraindicated in patients with known gastrointestinal bleeding or obstruction.
• Not suitable for patients with severe kidney or liver impairment.
• Should not be used in patients with Parkinson's disease.
• Contraindicated during pregnancy and breastfeeding.
• Avoid in patients with a history of seizures or epilepsy.
• Do not use in individuals with prostate enlargement or urinary retention.
• Not recommended for children and adolescents under 18 years of age.
• Should be used with caution in elderly patients with associated health issues.
• Discontinue use if signs of neuroleptic malignant syndrome (NMS) appear.

The side effects of Levosulpiride 25mg Tablet may include:

• Restlessness or akathisia (an intense urge to move)
• Drowsiness or sedation
• Extrapyramidal symptoms (EPS) such as tremors, muscle stiffness, and involuntary movements
• Weight gain
• Gastrointestinal disturbances like dry mouth, constipation, or indigestion
• Dizziness or lightheadedness
• Skin rashes or allergic reactions
• Enlargement of breasts in males (gynecomastia)

Following are the precautions and warnings for Levosulpiride 25mg Tablet:

• Do not take this medication if you are allergic to Levosulpiride or any similar antipsychotic drugs.
• Patients with a history of liver or kidney disease should use with caution, as it may require dosage adjustments.
• Levosulpiride may cause drowsiness and dizziness, so avoid driving or operating heavy machinery until you know how it affects you.
• Alcohol consumption should be avoided as it may increase the risk of certain side effects.
• Elderly patients may be more sensitive to the effects and side effects of this medication.
• This medication should be used with caution in patients with Parkinson's disease, as it may worsen symptoms.
• Pregnant and breastfeeding women should consult their doctor before taking Levosulpiride, as it may have potential risks for the fetus and infant.

Following are the drug interactions for Levosulpiride 25mg Tablet:

• Alcohol and other CNS depressants may enhance sedation when used with Levosulpiride, potentially affecting alertness and driving ability.
• Concomitant use with other dopamine antagonists can increase the risk of extrapyramidal symptoms.
• Levosulpiride may enhance the effects of anticoagulants, requiring close monitoring of coagulation parameters.
• It can interact with antihypertensive medications, leading to a possible additive effect on blood pressure.
• The absorption of Levosulpiride may be affected by antacids, resulting in reduced effectiveness.
• Combining Levosulpiride with medications that prolong the QT interval may increase the risk of cardiac arrhythmias.
• Caution is advised when using Levosulpiride with medications metabolized by CYP450 enzymes, as it may alter their metabolism.

Following are the food interactions for Levosulpiride 25mg Tablet:

• Alcohol consumption should be avoided as it can enhance the sedative effects, potentially leading to increased drowsiness and dizziness.
• Grapefruit and its juice should be consumed with caution as they can increase the drug's levels in the blood, possibly due to the inhibition of the enzyme CYP2D6.
• High-fat meals may delay the absorption of Levosulpiride, but this is generally not a cause for concern.
• Avoid caffeine-rich foods and beverages as they can interact with the medication, potentially increasing anxiety and restlessness.
• Avoid excessive salt intake, as Levosulpiride may cause sodium and water retention, which can lead to swelling and increased blood pressure.
• Ensure a balanced diet with adequate protein, as Levosulpiride may rarely cause protein loss through the kidneys.
• Maintain a consistent fluid intake, as Levosulpiride may cause dry mouth and constipation, which can be alleviated by staying hydrated.
• Consult your healthcare provider for specific dietary recommendations, especially if you have underlying health conditions that require dietary modifications.

Levosulpiride 25mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The tablets should be kept in their original packaging, tightly sealed to maintain their integrity. It is crucial not to expose the medication to excessive heat or cold, so avoid storing it in the bathroom, kitchen, or inside vehicles. Always check the expiration date, and if the tablets are expired or no longer needed, do not throw them into the trash or flush them. Contact your pharmacist or healthcare provider for guidance on safe disposal methods to prevent environmental contamination. Keep this medication away from children and pets to prevent accidental ingestion.

Following are the quick tips for Levosulpiride 20mg Tablet:

• Consult your doctor before use, especially if you have liver or kidney issues.
• Take the tablet as directed by your doctor, typically 1-2 tablets daily before meals.
• Swallow the tablet whole with water; do not crush or chew it.
• Maintain a consistent medication schedule for better effectiveness.
• Avoid alcohol consumption while taking this medication.
• Inform your doctor about all medications you are currently taking.
• Store in a cool, dry place, away from direct sunlight and moisture.
• Do not use if the packaging shows signs of tampering.